Patents by Inventor Zhibo CAI

Zhibo CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-BCMA SINGLE DOMAIN ANTIBODIES AND APPLICATION THEREOF
    Publication number: 20220251226
    Abstract: A group of anti-BCM single domain antibodies, as well as genes of the single domain antibodies in the group, a vector containing the single domain antibodies in the group, a chimeric antigen receptor, and a T cell modified by a chimeric antigen receptor, and detection and treatment application of the single domain antibodies in the group. The anti-BCMA single domain antibodies have high activity, high stability, high specificity, and high binding capability.
    Type: Application
    Filed: July 10, 2019
    Publication date: August 11, 2022
    Applicant: SHENZHEN PREGENE BIOPHARMA CO. LTD.
    Inventors: Jishuai ZHANG, Hongjian LI, ChaoLemeng BAO, Qinghua CAI, Yingying LI, Zongpei SONG, Yijin DING, Zhibo CAI
  • BCMA CHIMERIC ANTIGEN RECEPTOR BASED ON SINGLE DOMAIN ANTIBODY AND USE THEREOF
    Publication number: 20220218746
    Abstract: A chimeric antigen receptor (CAR) may be include: a BCMA binding domain, a transmembrane domain, a co-stimulatory domain, and an intracellular signaling domain, wherein the BCMA binding domain includes heavy chain complementarity determining regions HCDR1-3, and the amino acid sequences of the HCDR1-3 are successively as shown in SEQ ID NO: 1-3.
    Type: Application
    Filed: July 10, 2019
    Publication date: July 14, 2022
    Applicant: SHENZHEN PREGENE BIOPHARMA CO. LTD.
    Inventors: Jishuai ZHANG, Hongjian LI, Hongchang SU, Chaolemeng BAO, Zongpei SONG, Qinghua CAI, Yijin DING, Zhibo CAI