Abstract: The invention provides a wide-aperture spherical primary mirror off-axis afocal optical system, including a primary mirror, a secondary mirror and an aberration compensation mirror group. The primary mirror is a spherical reflector, the secondary mirror are higher-order aspherical reflectors. The primary mirror and the secondary mirror form an off-axis two-mirror system to compress the beam aperture. The aberration compensation mirror group is a coaxial reflective system that is used off-axis. The aberration compensation mirror group has focal power to produce compensation aberrations. The incident beam passes through and is reflected by the primary mirror and secondary mirror sequentially and enters the aberration compensation mirror group thereafter.

Abstract: A fast assembly method of an Offner spectral imaging optical system. The Offner spectral imaging optical system is a concentric or nearly concentric optical system, that is, its primary mirror (7), convex grating (5) and three-mirror (8) are all spherical, and respective centers of curvature coincide or basically coincide. Based on the self-collimation principle, the invention quickly determines the position of the center of curvature of the spherical mirror by observing the self-collimation image after the point light source is reflected by the spherical mirror. The assembly and adjustment method provided by the invention has the characteristics of fast assembly and adjustment speed, high precision, low requirements for assembly and adjustment environment and low required equipment cost, and can quickly and effectively complete the assembly and adjustment of the Offner spectral imaging optical system.

Abstract: The invention provides a wide-aperture spherical primary mirror off-axis afocal optical system, including a primary mirror, a secondary mirror and an aberration compensation mirror group. The primary mirror is a spherical reflector, the secondary mirror are higher-order aspherical reflectors. The primary mirror and the secondary mirror form an off-axis two-mirror system to compress the beam aperture. The aberration compensation mirror group is a coaxial reflective system that is used off-axis. The aberration compensation mirror group has focal power to produce compensation aberrations. The incident beam passes through and is reflected by the primary mirror and secondary mirror sequentially and enters the aberration compensation mirror group thereafter.

Abstract: A fast assembly method of an Offner spectral imaging optical system. The Offner spectral imaging optical system is a concentric or nearly concentric optical system, that is, its primary mirror (7), convex grating (5) and three-mirror (8) are all spherical, and respective centers of curvature coincide or basically coincide. Based on the self-collimation principle, the invention quickly determines the position of the center of curvature of the spherical mirror by observing the self-collimation image after the point light source is reflected by the spherical mirror. The assembly and adjustment method provided by the invention has the characteristics of fast assembly and adjustment speed, high precision, low requirements for assembly and adjustment environment and low required equipment cost, and can quickly and effectively complete the assembly and adjustment of the Offner spectral imaging optical system.

Abstract: An example apparatus is caused to receive a video sequence of a plurality of frames, and perform a number of operations as each of at least some of the frames is received but before all of the frames are received. The apparatus is caused to calculate a score for the frame, and compare the score for the frame to a predefined threshold. The apparatus is caused to cause output of the frame as a key frame in an instance in which the frame is received within a specified period of time and the score for the frame is above the predefined threshold. Otherwise, in an instance in which none of the scores for frames received within the specified period of time is above the predefined threshold, the apparatus is caused to cause output of one of the frames received within the specified period of time as a key frame.

Abstract: An example apparatus is caused to receive a video sequence of a plurality of frames, and perform a number of operations as each of at least some of the frames is received but before all of the frames are received. The apparatus is caused to calculate a score for the frame, and compare the score for the frame to a predefined threshold. The apparatus is caused to cause output of the frame as a key frame in an instance in which the frame is received within a specified period of time and the score for the frame is above the predefined threshold. Otherwise, in an instance in which none of the scores for frames received within the specified period of time is above the predefined threshold, the apparatus is caused to cause output of one of the frames received within the specified period of time as a key frame.

Abstract: The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I): or an enantiomer thereof, or an ester prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.

Abstract: The present invention is directed to a substituted pyrimidine compound of formula (I) or an enantiomer thereof, or a prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.

Abstract: The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase.

Abstract: The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of the formula wherein R1, R2, R4 and R5 are as described herein. More specifically, the compounds of this invention are inhibitors of ?-tryptase and are, therefore, useful as pharmaceutical agents. Additionally, this invention also discloses methods of preparation of substituted indolyl-piperidinyl benzylamines.

Abstract: The present invention extends to a compound of formula I: or a pharmaceutically acceptable salt of said compound, or a pharmaceutical composition comprising the compound of formula I and a pharmaceutically acceptable carrier. The invention is also directed to the use of a compound of formula I as an inhibitor of tryptase and for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by an inhibitor of tryptase. The invention further includes methods for the preparation of a compound of formula I.