Patents by Inventor Zhigan Jiang

Zhigan Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal forms of thiazole compound and application thereof
    Patent number: 11964969
    Abstract: Disclosed by the present invention are a crystal form A of a compound represented by formula (I), a compound represented by formula (II) and a crystal form B thereof, as well as an application of the crystal form A of the compound represented by formula (I), the compound represented by formula (II) and the crystal form B thereof in the preparation of a drug for the treatment diseases associated with the herpes simplex virus.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: April 23, 2024
    Assignee: PHAENO THERAPEUTICS CO., LTD
    Inventors: Weihua Shi, Zhigan Jiang, Haiying He
  • Crystal form of tri-cycle compound and application thereof
    Patent number: 11952388
    Abstract: Disclosed are crystal form A and crystal form B of a compound represented by formula (I), and application thereof in the preparation of medicaments for treating HBV-related diseases.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: April 9, 2024
    Assignee: Fujian Akeylink Biotechnology Co., Ltd.
    Inventors: Jing Wang, Zhigan Jiang, Haiying He, Yaxun Yang
  • LACTAM-MODIFIED POLYPEPTIDE COMPOUNDS
    Publication number: 20240067702
    Abstract: A class of lactam-modified polypeptide compounds and the use thereof in the preparation of a drug for treating related diseases.
    Type: Application
    Filed: December 2, 2021
    Publication date: February 29, 2024
    Inventors: Zhixiang PAN, Zhigan JIANG, Haiying HE, Guoping HU, Jian LI, Shuhui CHEN
  • AMINOPYRIDINE COMPOUND AND APPLICATION THEREOF
    Publication number: 20230416204
    Abstract: An aminopyridine compound, which is specifically a compound represented by formula (P), and a pharmaceutically acceptable salt thereof. The compound can be used to prepare drugs for treating deep fungal infections.
    Type: Application
    Filed: December 14, 2021
    Publication date: December 28, 2023
    Inventors: Shuhui CHEN, Xiaoping ZHENG, Zhigan JIANG, Haiying HE
  • COMBINATION COMPRISING TRICYCLE COMPOUND AND USE THEREOF IN PREPARATION OF MEDICAMENT FOR TREATING HBV
    Publication number: 20230190768
    Abstract: A combination comprising a tricycle compound and use thereof in the preparation of a medicament for treating HBV. The combination is a combination of a compound of formula (I) or a pharmaceutically acceptable salt thereof and any one drug in the following groups a-c: a. a hepatitis B surface antigen inhibitor, b. a reverse transcriptase inhibitor, and c. a hepatitis B surface antigen inhibitor and a reverse transcriptase inhibitor.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 22, 2023
    Inventors: Wenqiang WU, Dong ZHANG, Zhiqiang MA, Yixin ZHOU, John MAO, Zhigan JIANG, Jing WANG, Haiying HE
  • Thieno[2,3-c]pyridazin-4(1H)-one derivative and application thereof
    Patent number: 11680070
    Abstract: Disclosed are a thieno[2,3-c]pyridazin-4(1H)-one derivative as an ACC1 or ACC2 inhibitor and an application thereof in preparing a drug as an ACC1 or ACC2 inhibitor. In particular, disclosed is a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: June 20, 2023
    Assignee: MEDSHINE DISCOVERY INC.
    Inventors: Xiaoping Zheng, Zhigan Jiang, Haiying He, Jie Li, Zhen Gong, Jian Li, Shuhui Chen
  • Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof
    Patent number: 11673899
    Abstract: Disclosed are a crystal form of a thieno[2,3-c]pyridazine-4(1H)-one compound, a preparation method therefor and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: June 13, 2023
    Assignees: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD., MEDSHINE DISCOVERY INC.
    Inventors: Juan Yu, Zhiliang Chen, Shicong Wang, Tingting Yin, Kaili Jian, Xiaoping Zheng, Zhigan Jiang, Haiying He
  • COMPOUND HAVING KHK INHIBITORY EFFECT
    Publication number: 20230138901
    Abstract: A compound having a KHK inhibitory effect, or pharmaceutically acceptable salts thereof, and use thereof in the preparation of a medicament for treating a disease associated with KHK kinase abnormal expression. Provided is a compound as represented by formula (III) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 24, 2020
    Publication date: May 4, 2023
    Inventors: Zhixiang PAN, Haiying HE, Zhigan JIANG, Jianhua XIA, Lei ZHANG, Chen ZHANG, Jian LI, Shuhui CHEN
  • CRYSTAL FORMS OF THIAZOLE COMPOUND AND APPLICATION THEREOF
    Publication number: 20230132370
    Abstract: Disclosed by the present invention are a crystal form A of a compound represented by formula (I), a compound represented by formula (II) and a crystal form B thereof, as well as an application of the crystal form A of the compound represented by formula (I), the compound represented by formula (II) and the crystal form B thereof in the preparation of a drug for the treatment diseases associated with the herpes simplex virus.
    Type: Application
    Filed: July 5, 2019
    Publication date: April 27, 2023
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Weihua SHI, Zhigan JIANG, Haiying HE
  • CRYSTAL FORM OF THIENO[2,3-C]PYRIDAZINE-4(1H)-ONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230070611
    Abstract: Disclosed are a crystal form of a thieno[2,3-c]pyridazine-4(1H)-one compound, a preparation method therefor and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.
    Type: Application
    Filed: December 4, 2020
    Publication date: March 9, 2023
    Inventors: Juan YU, Zhiliang CHEN, Shicong WANG, Tingting YIN, Kaili JIAN, Xiaoping ZHENG, Zhigan JIANG, Haiying HE
  • Crystal form as inhibitor of ACC1 and ACC2, and preparation method therefor and use thereof
    Patent number: 11578081
    Abstract: Disclosed are a crystal form (I) as an inhibitor of ACC1 and ACC2, a preparation method therefor, and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: February 14, 2023
    Assignees: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD., MEDSHINE DISCOVERY INC.
    Inventors: Fei Hong, Jinming Huang, Jinxia Lin, Yichao Zhuang, Zhiyi Luo, Xiaoping Zheng, Zhigan Jiang, Haiying He
  • CRYSTAL FORM AS INHIBITOR OF ACC1 AND ACC2, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230034132
    Abstract: Disclosed are a crystal form (I) as an inhibitor of ACC1 and ACC2, a preparation method therefor, and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2.
    Type: Application
    Filed: December 4, 2020
    Publication date: February 2, 2023
    Applicants: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD., MEDSHINE DISCOVERY INC.
    Inventors: Fei HONG, Jinming HUANG, Jinxia LIN, Yichao ZHUANG, Zhiyi LUO, Xiaoping ZHENG, Zhigan JIANG, Haiying HE
  • 2H-BENZOPYRAN DERIVATIVES AS CRAC INHIBITORS
    Publication number: 20220380356
    Abstract: A class of compounds that have a pyrazine structure, specifically disclosed is a compound represented by formula, isomers or pharmaceutically acceptable salts thereof, and an application thereof in the preparation of CRAC inhibitors.
    Type: Application
    Filed: September 25, 2020
    Publication date: December 1, 2022
    Inventors: Yaxun YANG, Zhigan JIANG, Jianhua XIA, Wei WEI, Haiying HE, Shuhui CHEN
  • Amorphous pyrrolidine derivative as PPAR agonist and preparation method thereof
    Patent number: 11396493
    Abstract: The present invention relates to an amorphous pyrrolidine derivative as a PPAR agonist and a preparation method thereof.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: July 26, 2022
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Zhiliang Yuan, Zhigan Jiang, Haiying He, Xiao Zhang, Jiwen Xu, Weixiang Zhou, Jian Li, Shuhui Chen
  • Salt and crystal form of modified andrographolide compound and preparation method thereof
    Patent number: 11299482
    Abstract: The present invention provides a salt and crystal form of a modified andrographolide compound and a preparation method and pharmaceutical use thereof.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: April 12, 2022
    Assignees: Medshine Discovery, Inc., Heilongjiang Zhenbaodao Pharmaceutical Co, LTD
    Inventors: Jianhua Xia, Zhigan Jiang, Haiying He, Jing Wang
  • SALT AND CRYSTAL FORM OF MODIFIED ANDROGRAPHOLIDE COMPOUND AND PREPARATION METHOD THEREOF
    Publication number: 20210284630
    Abstract: The present invention provides a salt and crystal form of a modified andrographolide compound and a preparation method and pharmaceutical use thereof.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 16, 2021
    Applicants: MEDSHINE DISCOVERY INC., HEILONGJIANG ZHENBAODAO PHARMACEUTICAL CO, LTD
    Inventors: Jianhua XIA, Zhigan JIANG, Haiying HE, Jing WANG
  • CRYSTAL FORMS OF THIAZOLE COMPOUND AND APPLICATION THEREOF
    Publication number: 20210276993
    Abstract: Disclosed by the present invention are a crystal form A of a compound represented by formula (I), a compound represented by formula (II) and a crystal form B thereof, as well as an application of the crystal form A of the compound represented by formula (I), the compound represented by formula (II) and the crystal form B thereof in the preparation of a drug for the treatment diseases associated with the herpes simplex virus.
    Type: Application
    Filed: July 5, 2019
    Publication date: September 9, 2021
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Weihua SHI, Zhigan JIANG, Haiying HE
  • THIENO[2,3-C]PYRIDAZIN-4(1H)-ONE DERIVATIVE AND APPLICATION THEREOF
    Publication number: 20210238190
    Abstract: Disclosed are a thieno[2,3-c]pyridazin-4(1H)-one derivative as an ACC1 or ACC2 inhibitor and an application thereof in preparing a drug as an ACC1 or ACC2 inhibitor. In particular, disclosed is a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 5, 2019
    Publication date: August 5, 2021
    Inventors: Xiaoping ZHENG, Zhigan JIANG, Haiying HE, Jie LI, Zhen GONG, Jian LI, Shuhui CHEN
  • CRYSTAL FORM OF TRI-CYCLE COMPOUND AND APPLICATION THEREOF
    Publication number: 20210230188
    Abstract: Disclosed are crystal form A and crystal form B of a compound represented by formula (I), and application thereof in the preparation of medicaments for treating HBV-related diseases.
    Type: Application
    Filed: August 23, 2019
    Publication date: July 29, 2021
    Inventors: Jing WANG, Zhigan JIANG, Haiying HE, Yaxun YANG
  • Tri-cycle compound and applications thereof
    Patent number: 11053260
    Abstract: Disclosed in the present invention are a compound represented by formula (I), a tautomer thereof or a pharmaceutically acceptable salt, and applications thereof in the preparation of drugs for treating HBV-related diseases.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: July 6, 2021
    Assignee: FUJIAN COSUNTER PHARMACEUTICAL CO., LTD.
    Inventors: Haiying He, Jing Wang, Zhigan Jiang, Yaxun Yang, Peng Shao, Chen Zhang, Jian Li, Shuhui Chen