Patents by Inventor Zhigang Tian
Zhigang Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124615Abstract: Provided are a bispecific antibody and use thereof. The recombinant antibody includes: a CDR Sequence selected from at least one of CD3 antibody variable region CDR sequences: SEQ ID NO: 1 to SEQ ID NO: 6, and B7H6 antibody variable region CDR sequences: SEQ ID NO: 7 to SEQ ID NO: 12; or an amino acid sequence having at least 95% identity thereto. The recombinant antibodies prepared according to the present application can simultaneously target CD3 and B7H6 antigens, and they have a. significantly prolonged half-life, exhibiting a stronger tumor-inhibiting ability than single-target antibodies.Type: ApplicationFiled: December 20, 2023Publication date: April 18, 2024Inventors: Zhigang TIAN, Ying CHENG, Weihua XIAO, Guoshuai CAO, Haoyu SUN, Rui SUN
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Publication number: 20240121511Abstract: An example method for camera processing includes detecting a first region of interest for image content captured with a primary camera, detecting a second region of interest for image content captured with a secondary camera, comparing the first region of interest and the second region of interest, determining a first lens position for a secondary camera lens of the secondary camera based on an autofocus process for the secondary camera, determining a second lens position for the secondary camera lens of the secondary camera based on a determined lens position for a primary camera lens of the primary camera, determining a lens position for the secondary camera lens based on the first lens position or the second lens position based at least in part on the comparison, and causing the secondary camera to capture images with the secondary camera lens at the determined lens position.Type: ApplicationFiled: April 28, 2021Publication date: April 11, 2024Inventors: Jintao Xu, Yaoyao Hou, Mingchen Gao, Xiaocheng Wang, Zhigang Tian
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Publication number: 20240067782Abstract: An aluminum borate whisker reinforced and toughened non-metallic matrix composite is provided, which specifically includes a non-metallic material reinforced and toughened with aluminum borate whiskers. The composite exhibits a higher bending strength and fracture toughness and a higher wear resistance. A method for preparing the composite is also provided. The method includes mixing the aluminum borate whiskers and the non-metallic material to form a mixture; and sintering the mixture by a vacuum hot press method, or molding the mixture.Type: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Inventors: Yue Shi, Bi Jia, Jinliang Shi, Zhigang Zou, Yong Zhou, Yongjiang Di, Yin Liu, Huichao He, Rong Wang, Xueyi Wang, Hao Tian, Jun Zhu, Rui Tang, Xingyu Chen, Danxia Zhang
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Publication number: 20230262322Abstract: Techniques and systems are provided for improving one or more image capture operations. In some examples, a system detects a user input corresponding to a selection of a location within an image frame. The system determines that the image frame includes an object at least partially within a region of interest of the image frame, the region of interest including the selected location and having a predetermined size or a predetermined shape. The system then adjusts the region of interest based at least in part on the determination and performs one or more image capture operations on image data within the adjusted region of interest.Type: ApplicationFiled: October 22, 2020Publication date: August 17, 2023Inventors: Yaoyao HOU, Xiaocheng WANG, Zhigang TIAN
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Publication number: 20230227572Abstract: Provided is an antibody or antibody fragment. The antibody or the antibody fragment includes HCDR1 selected from GYTFSSFS, GYTFSTFA, or GYSFTAYT, HCDR2 selected from ILPGSNST, ILPGINNT, ILPGGNNT, or INPYNGGT, and HCDR3 selected from SSYWFAY, STYWFAY, or AREGNYYGSRGDFDY; and LCDR1 selected from QSLLNSGNQKNY or QTIVTN, LCDR2 selected from GAS or YAS, and LCDR3 selected from QNAHSYPPT, QNAHSYPPA, or QQSHSWPFT. The provided antibody can be used for treating cancer.Type: ApplicationFiled: January 27, 2023Publication date: July 20, 2023Applicant: HEFEI TG IMMUNOPHARMA CO., LTD.Inventors: Zhigang TIAN, Yangyang LI, Weihua XIAO, Rui SUN, Haoyu SUN
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Publication number: 20220316939Abstract: A smart wave energy converter may include a reconfigurable floater; a reference wave frequency measurement module; a central control module; a submerged buoyancy element; one or more power take-off devices; and an anchoring system. The reconfigurable floater may be connected to the submerged buoyancy element by the one or more power take-off devices. The submerged buoyance element may be connected to the anchoring system. The reconfigurable floater may include one or more mechanisms to alter a natural heave frequency of the reconfigurable floater. The reference wave frequency measurement module may measure a frequency of a wave state and transmit a measured frequency to the central control module. The central control module may adjust a property of the one or more mechanisms to match the natural heave frequency of the reconfigurable floater to the measured frequency.Type: ApplicationFiled: April 1, 2022Publication date: October 6, 2022Applicant: Exmar Offshore CompanyInventor: Zhigang Tian
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Publication number: 20220306244Abstract: A split mooring system may include at least two vessels in a body of water and a plurality of mooring lines. The plurality of mooring lines may be attached to the at least two vessels and configured to fix and maintain a position of the at least two vessels in the body of water relative to each other. A first vessel of the at least two vessels may be adjacent to a second vessel of the at least two vessels. The plurality of mooring lines may be attached to sides of the first vessel and the second vessel. The sides of the first vessel and the second vessel with mooring lines may face open water of the body of water.Type: ApplicationFiled: March 1, 2022Publication date: September 29, 2022Applicant: Exmar Offshore CompanyInventors: Otto DaSilva, Zhigang Tian, Branka Radanovic
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Patent number: 10919978Abstract: The present application provides an antibody or antibody fragment capable of binding to a lung-specific X protein and being used to treat a tumor, and a use thereof. The antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6. Alternatively, the antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 7, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 8, SEQ ID NO: 5, and SEQ ID NO: 6. The antibody is a chimeric antibody.Type: GrantFiled: May 25, 2017Date of Patent: February 16, 2021Assignee: IMMUNOPHARMACEUTIC INSTITUTE OF HEFEI RUIDA CO., LTD.Inventors: Zhigang Tian, Haiming Wei, Xiaohu Zheng, Rui Sun, Weihua Xiao, Dan Liu, Baoru Wang
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Publication number: 20190322758Abstract: The present application provides an antibody or antibody fragment capable of binding to a lung-specific X protein and being used to treat a tumor, and a use thereof. The antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6. Alternatively, the antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 7, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 8, SEQ ID NO: 5, and SEQ ID NO: 6. The antibody is a chimeric antibody.Type: ApplicationFiled: May 25, 2017Publication date: October 24, 2019Applicant: Immunopharmaceutic Institute of Hefei Ruida Co., Ltd.Inventors: Zhigang Tian, Haiming Wei, Xiaohu Zheng, Rui Sun, Weihua Xiao, Dan Liu, Baoru Wang
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Patent number: 8750199Abstract: An apparatus for performing a soft handoff including a power estimator, cell selector, and feedback channel generator. The power estimator receives a plurality of pilot signals that each correspond to an associated base station within an active set registry, and estimates a power level for each of the plurality of pilot signals. The cell selector is coupled to the power estimator, and is configured to select one or more base stations within the active set registry for selective blanking of a corresponding one or more of the plurality of pilot signals during a soft handoff operation. The feedback channel generator is coupled to the cell selector, and is configured to generate a cell selection feedback signal indicating the one or more base stations, where the cell selection feedback signal is subsequently transmitted to the one or more base stations, and where the cell selection feedback signal directs the one or more base stations to perform the selective blanking.Type: GrantFiled: November 23, 2009Date of Patent: June 10, 2014Assignee: VIA Telecom Co., Ltd.Inventors: Hong-Kui Yang, Jian Gu, Tingting Miao, Shu Wang, Zhigang Tian
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Patent number: 8428109Abstract: A communication device wirelessly coupled to another communication device. The communication device includes a first transmitter and a first receiver. The first transmitter is configured to transmit first power control bit information to the base station over a reverse link. The first transmitter has a timeline manager, configured to transmit the first power control bit information at a first rate according to a first pattern within a frame. The first receiver is configured to receive second power control bit information from the another communication device over a forward link. The first receiver has an adaptive controller, configured to determine the first rate and the first pattern. The first rate and the first pattern are selected from a plurality of rates and patterns available for transmission of the first power control bit information and the second power control bit information.Type: GrantFiled: January 21, 2010Date of Patent: April 23, 2013Assignee: VIA Telecom Inc.Inventors: Hong-Kui Yang, Shu Wang, Kraig Lamar Anderson, Jian Gu, Tingting Miao, Zhigang Tian
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Publication number: 20100202501Abstract: A communication device wirelessly coupled to another communication device. The communication device includes a first transmitter and a first receiver. The first transmitter is configured to transmit first power control bit information to the base station over a reverse link. The first transmitter has a timeline manager, configured to transmit the first power control bit information at a first rate according to a first pattern within a frame. The first receiver is configured to receive second power control bit information from the another communication device over a forward link. The first receiver has an adaptive controller, configured to determine the first rate and the first pattern. The first rate and the first pattern are selected from a plurality of rates and patterns available for transmission of the first power control bit information and the second power control bit information.Type: ApplicationFiled: January 21, 2010Publication date: August 12, 2010Applicant: VIA TELECOM, INC.Inventors: Hong-Kui Yang, Shu Wang, Kraig Lamar Anderson, Jian Gu, Tingting Miao, Zhigang Tian
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Publication number: 20100136979Abstract: An apparatus for performing a soft handoff including a power estimator, cell selector, and feedback channel generator. The power estimator receives a plurality of pilot signals that each correspond to an associated base station within an active set registry, and estimates a power level for each of the plurality of pilot signals. The cell selector is coupled to the power estimator, and is configured to select one or more base stations within the active set registry for selective blanking of a corresponding one or more of the plurality of pilot signals during a soft handoff operation. The feedback channel generator is coupled to the cell selector, and is configured to generate a cell selection feedback signal indicating the one or more base stations, where the cell selection feedback signal is subsequently transmitted to the one or more base stations, and where the cell selection feedback signal directs the one or more base stations to perform the selective blanking.Type: ApplicationFiled: November 23, 2009Publication date: June 3, 2010Applicant: VIA TELECOM, INC.Inventors: Hong-Kui Yang, Jian Gu, Tingting Miao, Shu Wang, Zhigang Tian