Patents by Inventor Zhigao Niu

Zhigao Niu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250101777
    Abstract: A self-adjusting vehicle door lock catch assembly includes: a lock catch body, which includes a base and a lock cylinder, where the base is provided with a bolt through-hole, a first surface of the base is provided with a slide groove, and the lock cylinder is fixedly connected to the first surface of the base; a floating adjustment piece, which is provided in the slide groove, where the floating adjustment piece is provided with an opening, and the bolt through-hole has a diameter larger than that of the opening of the floating adjustment piece; a fastener, where the diameter of the opening of the floating adjustment piece matches a size of the fastener; and a limit block which is connected to the base, where a limit groove is provided between the limit block and the base, and the limit block limits the lock catch body through the limit groove.
    Type: Application
    Filed: December 6, 2024
    Publication date: March 27, 2025
    Applicants: Zhejiang ZEEKR Intelligent Technology Co., Ltd., Zhejiang Geely Holding Group Co., Ltd.
    Inventors: Xiaonan ZHAO, Lingjie XU, Duo LI, Zhigao NIU, Xiaoyuan JIANG, Dacheng YANG
  • Publication number: 20220000160
    Abstract: The invention relates to a flavonoid delivery system comprising a co-precipitate of a hydrophobic flavonoid and a protein. The flavonoid delivery system comprises a high ratio of flavonoid to protein, allowing food products to be fortified with relatively large amounts of flavonoid without compromising the sensory properties of the food product.
    Type: Application
    Filed: November 7, 2019
    Publication date: January 6, 2022
    Inventors: Abby Kerrin Thompson, Alejandra Acevedo Fani, Ali Rashidinejad, Harjinder Singh, Simon Derek Miller Loveday, Zhigao Niu
  • Patent number: 10471020
    Abstract: The present invention generally relates to particles, including nanoparticles, for example, for drug delivery or other applications. Certain aspects of the present invention are generally directed to particles, such as nanoparticles, comprising an inner portion and a coating. The inner portion may contain insulin or other therapeutic molecules for delivery to a living organism. In some cases, the molecules may be electrostatically complexed with an oppositely-charged peptide, such as an oligoarginine, or other species. The therapeutic molecules may also be water soluble. In some cases, the peptide may be conjugated to a hydrophobic portion, such as cholesterol, lauric acid, or a fatty acid chain. This hydrophobic modification may facilitate complex formation with the therapeutic molecule and the stability of the resulting complex. The complex typically is surrounded by a coating, which may protect the complex. For example, the coating may include polymers such as poly(glutamic acid) and poly(ethylene glycol).
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: November 12, 2019
    Assignee: Universidade de Santiago de Compostela
    Inventors: Maria Josefa Alonso Fernandez, Zhigao Niu, Manuel Jesus Santander Ortega
  • Publication number: 20180078510
    Abstract: The present invention generally relates to particles, including nanoparticles, for example, for drug delivery or other applications. Certain aspects of the present invention are generally directed to particles, such as nanoparticles, comprising an inner portion and a coating. The inner portion may contain insulin or other therapeutic molecules for delivery to a living organism. In some cases, the molecules may be electrostatically complexed with an oppositely-charged peptide, such as an oligoarginine, or other species. The therapeutic molecules may also be water soluble. In some cases, the peptide may be conjugated to a hydrophobic portion, such as cholesterol, lauric acid, or a fatty acid chain. This hydrophobic modification may facilitate complex formation with the therapeutic molecule and the stability of the resulting complex. The complex typically is surrounded by a coating, which may protect the complex. For example, the coating may include polymers such as poly(glutamic acid) and poly(ethylene glycol).
    Type: Application
    Filed: November 14, 2016
    Publication date: March 22, 2018
    Applicant: Universidade de Santiago de Compostela
    Inventors: Maria Josefa Alonso Fernandez, Zhigao Niu, Manuel Jesus Santander Ortega
  • Publication number: 20170087096
    Abstract: Nanocapsule systems of at least one active pharmaceutical ingredient selected from the group consisting of at least one insulin, insulin analogue, insulin derivative, glucagon-like peptide-1 receptor agonist (GLP1 R agonist) and/or dual GLP-1 receptor/glucagon receptor agonist and/or or any combination thereof are disclosed.
    Type: Application
    Filed: June 12, 2015
    Publication date: March 30, 2017
    Inventors: Gudrun Lenherr, Noemi Csaba, Nomceba Lungile Thwala, Zhigao Niu, Maria José Alonso