Patents by Inventor Zhiguang Xu

Zhiguang Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11860354
    Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: January 2, 2024
    Assignee: Scanogen Inc.
    Inventors: Zhiguang Xu, Alfredo Andres Celedon
  • Publication number: 20230165674
    Abstract: A multi-layer intraocular lens (IOL) includes a lens body, including an anterior diffractive optics layer, comprising a first biocompatible material, and a posterior diffractive optics layer, comprising a second biocompatible material that is different from the first biocompatible material. The anterior diffractive optics layer and the posterior diffractive optics layer are sealed in a peripheral non-optic portion of the lens body with a gap between the anterior diffractive optics layer and the posterior diffractive optics layer.
    Type: Application
    Filed: November 15, 2022
    Publication date: June 1, 2023
    Inventors: Shinwook Lee, Xin Hong, Myoung-Taek Choi, Zhiguang Xu
  • Publication number: 20230039492
    Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.
    Type: Application
    Filed: October 25, 2022
    Publication date: February 9, 2023
    Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
  • Patent number: 11505818
    Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 22, 2022
    Assignee: Scanogen Inc.
    Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
  • Publication number: 20220276480
    Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
    Type: Application
    Filed: May 12, 2022
    Publication date: September 1, 2022
    Inventors: ZHIGUANG XU, ALFREDO ANDRES CELEDON
  • Patent number: 11360296
    Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: June 14, 2022
    Assignee: Scanogen Inc
    Inventors: Zhiguang Xu, Alfredo Andres Celedon
  • Patent number: 10879672
    Abstract: A semiconductor laser (100) and a method for processing the semiconductor laser are provided, so that modulation bandwidth can be increased.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: December 29, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jian Chen, Jing Hu, Zhiguang Xu
  • Publication number: 20200400932
    Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Inventors: ZHIGUANG XU, ALFREDO ANDRES CELEDON
  • Patent number: 10855375
    Abstract: Embodiments provide an optical transceiver assembly for resolving a problem that an optical assembly has a large size. The optical transceiver assembly may include a first cavity, a second cavity and WDMs. The first cavity may include at least two optical receivers, which may be configured to receive light of different wavelengths, respectively. The second cavity may include at least two optical transmitters, may be configured to emit light of different wavelengths, respectively. Each of the at least two optical receivers and each of the at least two optical transmitters may correspond to different WDMs, respectively. The WDM corresponding to one of the at least wo optical receivers can be configured to: separate, from light emitted from an optical fiber, light of a wavelength receivable by the corresponding optical receiver, transmit the light to the corresponding optical receiver, and reflect the other wavelengths.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: December 1, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Zhiguang Xu, Yue Wen
  • Patent number: 10768406
    Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: September 8, 2020
    Assignee: Scanogen Inc.
    Inventors: Zhiguang Xu, Alfredo Andres Celedon
  • Patent number: 10644481
    Abstract: An optical component packaging structure includes a base, a sealing cover, and a cooler. The base includes a mounting surface and a back surface that faces a direction opposite to that faced by the mounting surface. The cooler includes a cooling plate, a heat dissipation plate disposed opposite to the cooling plate, and a conductive connection body connecting the cooling plate and the heat dissipation plate. The cooling plate includes a cooling surface. The cooler is partially built in the base. The cooling plate faces a direction the same as the mounting surface. The sealing cover covers the mounting surface, and the sealing cover and the mounting surface form a sealing cavity. The cooling surface is located inside the sealing cavity. The heat dissipation plate protrudes from the back surface and is sealedly connected to the base.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: May 5, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Yue Wen, Zhiguang Xu, Sulin Yang
  • Publication number: 20190238233
    Abstract: Embodiments provide an optical transceiver assembly for resolving a problem that an optical assembly has a large size. The optical transceiver assembly may include a first cavity, a second cavity and WDMs. The first cavity may include at least two optical receivers, which may be configured to receive light of different wavelengths, respectively. The second cavity may include at least two optical transmitters, may be configured to emit light of different wavelengths, respectively. Each of the at least two optical receivers and each of the at least two optical transmitters may correspond to different WDMs, respectively. The WDM corresponding to one of the at least wo optical receivers can be configured to: separate, from light emitted from an optical fiber, light of a wavelength receivable by the corresponding optical receiver, transmit the light to the corresponding optical receiver, and reflect the other wavelengths.
    Type: Application
    Filed: April 11, 2019
    Publication date: August 1, 2019
    Inventors: Zhiguang XU, Yue WEN
  • Publication number: 20190112641
    Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.
    Type: Application
    Filed: December 12, 2018
    Publication date: April 18, 2019
    Applicant: Scanogen Inc.
    Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
  • Patent number: 10209444
    Abstract: An arrayed waveguide grating includes an input/output waveguide 1, an input/output waveguide 2, a slab waveguide, an arrayed waveguide 1, a reflection zone 1, an arrayed waveguide 2, and a reflection zone 2. The input/output waveguide 1 and the input/output waveguide 2 are located on a same side of the slab waveguide, and are coupled to the slab waveguide. The reflection zone 1 is configured to reflect a light wave in a first band, and to transmit a light wave in a second band. The reflection zone 2 is configured to reflect the light wave in the second band. It is implemented that a single arrayed waveguide grating outputs light waves with different adjacent channel wavelength spacings, and a quantity of devices used in a system in which an uplink adjacent channel wavelength spacing and a downlink adjacent channel wavelength spacing are asymmetrical is further reduced.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 19, 2019
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jing Hu, Enyu Zhou, Zhiguang Xu
  • Patent number: 10179930
    Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: January 15, 2019
    Assignee: Scanogen Inc.
    Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
  • Publication number: 20190013643
    Abstract: An optical component packaging structure includes a base, a sealing cover, and a cooler. The base includes a mounting surface and a back surface that faces a direction opposite to that faced by the mounting surface. The cooler includes a cooling plate, a heat dissipation plate disposed opposite to the cooling plate, and a conductive connection body connecting the cooling plate and the heat dissipation plate. The cooling plate includes a cooling surface. The cooler is partially built in the base. The cooling plate faces a direction the same as the mounting surface. The sealing cover covers the mounting surface, and the sealing cover and the mounting surface form a sealing cavity. The cooling surface is located inside the sealing cavity. The heat dissipation plate protrudes from the back surface and is sealedly connected to the base.
    Type: Application
    Filed: August 24, 2018
    Publication date: January 10, 2019
    Inventors: Yue WEN, Zhiguang XU, Sulin YANG
  • Patent number: 10128970
    Abstract: A circuit board of the optical module comprises: a first electrical interface is configured to connect an electrical interface of a board or a second electrical interface of another optical module, and a second electrical interface is configured to connect a first electrical interface of another optical module; a first optical port is configured to connect an optical transmission device or a second optical port of another optical module, and a second optical port is configured to connect an optical receiving device or a first optical port of another optical module; and a optical transceiver assembly multiplexes downstream light and demultiplexes upstream light. The optical module provided in solutions of the present invention can be flexibly combined with another optical module, enabling flexible and gradual upgrade of an optical module bandwidth according to a user requirement by using various combination manners.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: November 13, 2018
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Yue Wen, Zhiguang Xu, Huafeng Lin, Xiaoping Zhou, Jing Hu
  • Publication number: 20180299618
    Abstract: An arrayed waveguide grating includes an input/output waveguide 1, an input/output waveguide 2, a slab waveguide, an arrayed waveguide 1, a reflection zone 1, an arrayed waveguide 2, and a reflection zone 2. The input/output waveguide 1 and the input/output waveguide 2 are located on a same side of the slab waveguide, and are coupled to the slab waveguide. The reflection zone 1 is configured to reflect a light wave in a first band, and to transmit a light wave in a second band. The reflection zone 2 is configured to reflect the light wave in the second band. It is implemented that a single arrayed waveguide grating outputs light waves with different adjacent channel wavelength spacings, and a quantity of devices used in a system in which an uplink adjacent channel wavelength spacing and a downlink adjacent channel wavelength spacing are asymmetrical is further reduced.
    Type: Application
    Filed: June 22, 2018
    Publication date: October 18, 2018
    Inventors: Jing HU, Enyu ZHOU, Zhiguang XU
  • Publication number: 20180212403
    Abstract: A semiconductor laser (100) and a method for processing the semiconductor laser are provided, so that modulation bandwidth can be increased.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 26, 2018
    Inventors: Jian CHEN, Jing HU, Zhiguang XU
  • Patent number: 9866318
    Abstract: A method includes monitoring a power value of output light of the laser and a power value of reflected light, obtaining an insertion loss value according to the power value of the output light, the power value of the reflected light, and a parameter of a Faraday rotation reflector, obtaining a bias current value according to the insertion loss value, and adjusting the power value of the output light of the laser using the bias current value. The insertion loss value is obtained by detecting the power value of the reflected light obtained after the output light of the laser is reflected. Because the insertion loss value is a power loss value, of the output light of the laser, on a one-way link between the laser and the Faraday rotation mirror.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: January 9, 2018
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Heng Wang, Zhiguang Xu, Enyu Zhou