Patents by Inventor Zhihao Zhao

Zhihao Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250078137
    Abstract: Disclosed are a method and apparatus for generating an object combination, an electronic device, and a readable medium. After a worker executes a first operation, at least one object combination can be generated. Combination information corresponding to the at least one object combination is displayed on a recommendation page. The combination information includes description information, matching information and interactive controls of objects included in the object combination. Each of the at least one object combination includes at least two objects. At least two objects belonging to one object combination satisfy a preset matching condition.
    Type: Application
    Filed: August 28, 2024
    Publication date: March 6, 2025
    Inventors: Zhixin SHEN, Zhihao ZHAO, Haochen XU, Tianlong CUI, Junliang CHEN
  • Publication number: 20240292578
    Abstract: The heat dissipation device includes a liquid-cooling plate and a heat-exchange fin. The liquid-cooling plate has a first surface, a second surface opposite to the first surface, and a first side surface connected to the first surface and the second surface, where the first surface is used for installing of electronic components, and the heat-exchange fin is disposed on the second surface. The liquid-cooling plate defines a cooling flow channel in the liquid-cooling plate, and defines a liquid inlet and a liquid outlet on the first side surface, where both the liquid inlet and the liquid outlet are in communication with the cooling flow channel.
    Type: Application
    Filed: May 9, 2024
    Publication date: August 29, 2024
    Inventors: Liangyin GUO, Shaopeng GAN, Yati CHEN, Zhihao ZHAO
  • Publication number: 20240240126
    Abstract: Provided herein is a resource-independent and cost-efficient antimicrobial susceptibility testing (AST) system or apparatus that can rapidly process a large number of samples. The AST system includes a barcode-like cell sensor based on an adaptive linear filter array for implementing a fully automatic and microscope-free method for counting a very small volume of cells in samples, wherein suspended cells concentrate into microbars with various lengths proportional to the number of cells. The AST system also includes an on-chip culture that takes much less time than standard methods, thereby realizing a low-cost and resource-independent platform for portable AST, from which results can be obtained through a portable device such as a cell phone.
    Type: Application
    Filed: May 24, 2022
    Publication date: July 18, 2024
    Inventors: Kangning REN, Xiaowen CHU, Chiu Wing CHAN, Han SUN, Yisu WANG, Zhihao ZHAO, Sin Yung SIU
  • Patent number: 12006310
    Abstract: The present invention relates to the technical field of natural medicines, and in particular to a triterpenoid compound with an effect of improving glucose and lipid metabolism disorders, and preparation and application thereof. A novel triterpenoid compound was obtained by separation from Momordica charantia L. for the first time in the present invention. Studies on a mouse primary hepatocyte model and a 3T3-L1 preadipocyte model show that the novel triterpenoid compound in the present invention has activity of regulating glucose and lipid metabolism, and after combination with known triterpenoid compound Momordicoside G, the activity of regulating glucose and lipid metabolism is significantly higher than that of a single compound at the same dose, indicating that the novel triterpenoid compound and a complex thereof in the present invention can be used to improve glucose and lipid metabolism disorders and provide a new way for diabetes treatment.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: June 11, 2024
    Assignee: SERICULTURAL & AGRI-FOOD RESEARCH INSTITUTE GUANGDONG ACADEMY OF AGRICULTERAL SCIENCES
    Inventors: Mingwei Zhang, Yuanyuan Deng, Guang Liu, Yan Zhang, Zhencheng Wei, Pengfei Zhou, Ping Li, Zhihao Zhao, Xuchao Jia, Xiaojun Tang
  • Publication number: 20240008504
    Abstract: The present invention discloses powdered oil based on an olesome emusion and a preparation method and an application thereof. The preparation method includes the following steps: preparation of olesome emulsion of an oil stock, addition of a wall material and spray drying. The preparation method for the powdered oil provided by the present invention is based on an olesome emulsion system; and compared with the traditional preparation process for the powdered oil, the preparation method has many advantages that the prepared olesome emulsion does not contain hydrogenated vegetable oil and an exogenous emulsifier, is high in content of active oil accompaniments, and has an embedding rate close to 100 percent, a low production cost, strong storage stability and a certain natural oil stock flavor.
    Type: Application
    Filed: April 12, 2023
    Publication date: January 11, 2024
    Inventors: Zhihao ZHAO, Mingwei ZHANG, Yuanyuan DENG, Pengfei ZHOU, Zhencheng WEI, Yan ZHANG, Xiaojun TANG, Guang LIU, Ping LI
  • Publication number: 20230248717
    Abstract: An N-(3-hydroxypyridine-2-carbonyl)glycine-based antitumor drug sensitizer and an application thereof are provided. In the present disclosure, a compound of formula (I) can down-regulate PD-L1 of tumor cells, promote polarization of macrophages from M2 to M1, inhibit an expression of indoleamine 2,3-dioxygenase, and improve an immunotherapy curative effect. The compound can also reduce the expression of hypoxia-inducible factor-1? in tumor cells, down-regulate an expression of P-glycoprotein, enhance the killing effect of a chemotherapeutic drug on tumor cells, and enhance immunogenic cell death. The compound of formula (1) has a significantly improved antitumor effect after being used in combination with a chemotherapeutic drug and shows a desirable prospect for use.
    Type: Application
    Filed: October 29, 2020
    Publication date: August 10, 2023
    Applicant: ZHEJIANG UNIVERSITY
    Inventors: Youqing SHEN, Jing LIU, Zhihao ZHAO
  • Publication number: 20230022783
    Abstract: The present invention relates to the technical field of natural medicines, and in particular to a triterpenoid compound with an effect of improving glucose and lipid metabolism disorders, and preparation and application thereof. A novel triterpenoid compound was obtained by separation from Momordica charantia L. for the first time in the present invention. Studies on a mouse primary hepatocyte model and a 3T3-L1 preadipocyte model show that the novel triterpenoid compound in the present invention has activity of regulating glucose and lipid metabolism, and after combination with known triterpenoid compound Momordicoside G, the activity of regulating glucose and lipid metabolism is significantly higher than that of a single compound at the same dose, indicating that the novel triterpenoid compound and a complex thereof in the present invention can be used to improve glucose and lipid metabolism disorders and provide a new way for diabetes treatment.
    Type: Application
    Filed: July 1, 2022
    Publication date: January 26, 2023
    Inventors: MINGWEI ZHANG, YUNAYUAN DENG, GUANG LIU, YAN ZHANG, ZHENCHENG WEI, PENGFEI ZHOU, PING LI, ZHIHAO ZHAO, XUCHAO JIA, XIAOJUN TANG
  • Publication number: 20220240554
    Abstract: A method for stabilizing rice bran with complex enzyme involving enzymatic hydrolysis combined with thermal processing to stabilize rice bran, includes compounding at least one of glycosyl hydrolases such as cellulase, hemicellulase and alpha amylase into a complex enzyme solution, and performing enzymatic hydrolysis on the rice bran with the complex enzyme solution, and after enzymatic hydrolysis, performing thermal processing and inactivating enzyme treatment on rice bran using the moist-heat method, microwave method and/or extrusion expansion method, to prepare the stabilized rice bran. From the perspective of reducing bound lipase from rice bran, the glycosyl hydrolase is used to catalyze conversion of bound lipase in rice bran into free lipase, thereby effectively improving inactivation efficiency of rice bran lipase. The rice bran prepared using the method has characteristics of low residual activity of lipase and long shelf life, and may be directly applied to industries such as food and cosmetics.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 4, 2022
    Inventors: Guang Liu, Mingwei Zhang, Yuanyuan Deng, Zhencheng Wei, Yan Zhang, Xiaojun Tang, Ping Li, Pengfei Zhou, Zhihao Zhao, Zhiming Wang, Jiajia Wang, Na Liao
  • Publication number: 20220074027
    Abstract: A high-hardness composite oxide dispersion-strengthened tungsten alloy and a preparation method thereof are disclosed. The high-hardness composite oxide dispersion-strengthened tungsten alloy consists essentially of a tungsten phase, and nano-scale Y2O3 and ZrO2 particles dispersed in the tungsten phase, wherein there is a Y—Zr—O ternary phase structure at a coherent/semi-coherent interface.
    Type: Application
    Filed: July 13, 2021
    Publication date: March 10, 2022
    Applicant: Hefei University of Technology
    Inventors: Laima LUO, Zhihao Zhao, Yucheng Wu, Gang Yao, Xiang Zan, Xiaoyong Zhu
  • Patent number: D890752
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: July 21, 2020
    Assignee: Beijing Unicorn Technology Co., Ltd
    Inventors: Xi Huang, Yue He, Yue Wang, Zhihao Zhao, Liwei Chen, Jun Wang
  • Patent number: D899292
    Type: Grant
    Filed: June 14, 2020
    Date of Patent: October 20, 2020
    Inventor: Zhihao Zhao
  • Patent number: D899960
    Type: Grant
    Filed: June 14, 2020
    Date of Patent: October 27, 2020
    Inventor: Zhihao Zhao
  • Patent number: D912046
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: March 2, 2021
    Assignee: Beijing Unicorn Technology Co., Ltd
    Inventors: Xi Huang, Yue He, Yue Wang, Zhihao Zhao, Liwei Chen, Jun Wang