Patents by Inventor Zhihui BAI

Zhihui BAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240091282
    Abstract: A probiotic microcapsule for the treatment of reproductive tract infection and a preparation method and application thereof are provided. The probiotic microcapsule is obtained by coating probiotics with the coating material. The probiotics include one or several of Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus fermentum, Lactobacillus reuteri, Lactobacillus crimpus, Lactobacillus brevis, Lactobacillus salivary, Lactobacillus plantarum, Lactobacillus acidophilus, and Lactobacillus bulgaricus. As probiotics screened in reproductive tract, it has high safety; It endows probiotics with adhesion function to ensure their effect in the reproductive tract; It overcomes the defects of current antibiotic therapy; It is expected to be used in a variety of reproductive tract infectious diseases.
    Type: Application
    Filed: October 18, 2022
    Publication date: March 21, 2024
    Applicants: Tangyi Biomedical (Tianjin) Co., Ltd., Tangyi Holding (Shenzhen) Co., Ltd.
    Inventors: Bin ZHENG, Qinglu GUO, Yulin CAO, Shixiang CHENG, Zhihui BAI
  • Publication number: 20240091514
    Abstract: A transdermal double-layer microneedle based on hydrogen producing probiotics and its preparation method and application thereof are provided. The transdermal double-layer microneedle consists of a needle body and a backing layer. The raw material of the needle body includes hyaluronic acid and hyaluronidase. The raw material of the backing layer includes methacrylate anhydride gelatin and silk fibroin protein. The hydrogen producing bacteria are loaded in the microneedles, and the pore size of the matrix material is lower than the diameter of the probiotics, which will not lead to the leakage of bacteria and has high safety. Treatment of inflammatory skin diseases by gas has low side effects. The needle tip is loaded with hyaluronidase to increase the tissue space and improve the effect of gas treatment. It is expected to be used in psoriasis and other inflammatory skin diseases.
    Type: Application
    Filed: October 18, 2022
    Publication date: March 21, 2024
    Applicants: Tangyi Biomedical (Tianjin) Co., Ltd., Tangyi Holding (Shenzhen) Co., Ltd.
    Inventors: Bin ZHENG, Qinglu GUO, Yulin CAO, Shixiang CHENG, Zhihui BAI
  • Publication number: 20200392566
    Abstract: The present disclosure relates to a primer and a kit for rapid detection of bacteria and an application thereof, belonging to the technical field of bacterial detection. The present disclosure provides a primer for rapid detection of bacteria, a nucleotide sequence of a forward primer for the detection is shown in SEQ ID NO.1, and a nucleotide sequence of a reverse primer is shown in SEQ ID NO.2; a degenerate base W=A/T in the forward primer, and a degenerate base R=A/G in the reverse primer. The primer of the present disclosure may achieve rapid, wide, high-sensitivity and quantitative detection of bacteria, can be applied in the field of bacterial detection, and is more suitable for the clinical research and application of cells and stem cell-based products.
    Type: Application
    Filed: November 4, 2019
    Publication date: December 17, 2020
    Applicant: Shanghai East Hospital (East Hospital Affiliated to Tongji University)
    Inventors: Zhongmin LIU, Wenwen JIA, Zhihui BAI, Hongming TANG
  • Publication number: 20190230918
    Abstract: The kit for collection of umbilical cord, umbilical cord blood and placenta includes a collection case and a case cover hinged with the collection case. A tool box, a refrigeration box and a freezing box are arranged in the collection case. A liner plate is arranged in the tool box and provided with an accommodating trough, at least three storage troughs and several test tube troughs. An umbilical cord collection box, a placenta collection box and a blood collection bag are respectively arranged in the three storage troughs. A reagent bottle for containing a cell protection solution is arranged in the refrigeration box. Several ice bags are arranged in the freezing box.
    Type: Application
    Filed: August 11, 2016
    Publication date: August 1, 2019
    Applicant: CENTURY BIOSTRENGTH BEIJING Pty Ltd.
    Inventors: Yulin CAO, Xiayun LI, Zhihui BAI, Shihong LIU, Chengqian LU