Abstract: Methods for detecting a glitch at a high sampling rate are provided. In some embodiments, a method includes the following steps: S1, acquiring to-be-identified data; S2, processing the to-be-identified data to obtain normal sampling data; and S3, performing glitch identification on the to-be-identified data to obtain a glitch position of the normal sampling data. In other embodiments, the disclosure provides a system for detecting a glitch at a high sampling rate and for implementing the method for detecting a glitch at a high sampling rate. The system includes an acquisition unit and a glitch identification unit. The acquisition unit acquires and processes the to-be-identified data to obtain the normal sampling data, and the glitch identification unit performs glitch identification on the to-be-identified data to obtain the glitch position of the normal sampling data.

Abstract: A class of pyrimidoheterocyclic compounds, and specifically disclosed is a compound represented by formula (III) or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: A display module, including: a display panel; and a color film layer and a micro-lens layer, provided on a light-emitting side of the display panel; where, the color film layer includes a plurality of filter portions, and the micro-lens layer includes a plurality of first converging lenses and a plurality of second converging lenses; a gap is provided between two adjacent first converging lenses, and an orthographic projection of a first converging lens on the display panel is located within an orthographic projection of a filter portion on the display panel; a second converging lens is provided in the gap between two adjacent first converging lenses, and a vertex of the second converging lens is located between a vertex of the first converging lens and a bottom surface of the first converging lens.

Abstract: A multi-layer circuit board, successively constituted by surface sticking layer, single-layer circuit board, middle sticking layer, single-layer circuit board, surface sticking layer, said multi-layer circuit board is provided with a hole, a hole wall of said hole is formed with conductive seed layer, and partial outer surface of said surface sticking layer is formed with a circuit pattern layer of conductive seed layer, wherein said conductive seed layer comprises a ion implantation layer implanting below the hole wall of said hole and below partial outer surface of said surface sticking layer.

Abstract: A method for vendor-agnostic processing of data for monitoring a real-time operational status of a telecommunications network includes routing cell site status indications from a broker node to an in-memory processing engine. The cell site status indications are based on parameter data. A first application of the in-memory processing engine generates unique identifiers that associate each cell site status indication to a particular cell site identification code and generate feedback for the broker node including modified cell site status indications including the unique identifiers. The broker node forwards the modified cell site status indications to a second application of the in-memory processing. The second application processes the modified broker messages to extract the second parameter data from the modified cell site status indications. The in-memory processing engine generates a dataset including the second parameter data associated with the unique identifiers by the in-memory processing engine.

Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.

Abstract: Methods are disclosed for treating a cone rod homeobox transcription factor (CRX) autosomal dominant retinopathy in a subject. These methods include administering to the subject an effective amount of a nucleic acid molecule comprising a retinal specific promoter operably linked to a nucleic acid molecule encoding a CRX protein. Compositions are disclosed that include an effective amount of a nucleic acid molecule comprising a retinal specific promoter operably linked to a nucleic acid molecule encoding CRX, for use in treating a CRX autosomal dominant retinopathy in a subject. A retinal specific promoter is disclosed that includes the nucleotide sequence of SEQ ID NO: 1.

Abstract: A lightning strike probability-based coordinated power control method for an energy storage system and a load adjusts output power of an energy storage system and a regulatable load based on a real-time predicted lightning strike probability. This reduces a correlation between a power grid in a lightning region and an external power grid, minimizes impact of a lightning strike if any on the external power grid, and decreases an economic loss due to the lightning strike in the lightning region. The present disclosure establishes a relationship between the output power of the energy storage system, the regulated power of the regulatable load, and a lightning strike probability in a same region, and then regulates the power of the energy storage system and the regulatable load in real time based on the lightning strike probability.

Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.

Abstract: Methods are provided for protecting a subject from retinal degeneration, and/or treating uveitis, retinitis or chorioretinitis in a subject. The methods include selecting a subject with uveitis, retinitis, or chorioretinitis and/or in need of protection from retinal degeneration; and administering locally to the eye of the subject a therapeutically effective amount of: (a) a polypeptide comprising amino acids 1-182 of an interleukin (IL)-34, a variant of IL-34, or an Fc fusion protein of IL-34, wherein the polypeptide, variant, or Fc fusion protein is i) anti-inflammatory or ii) neuroprotective; or (b) a nucleic acid molecule encoding the polypeptide, variant, or Fc fusion protein. A pharmaceutical composition for use in any of the disclosed methods is also provided.

Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.

Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.

Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.

Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.

Abstract: The present disclosure discloses a method for evaluating a search prompting system and a corresponding apparatus. The method includes: extracting corresponding assessment terms at random according to an assessment target; acquiring in sequence a minimum number of words that needs to be entered to cover each of the assessment terms; calculating a corresponding coverage efficiency factor and a corresponding prompt efficiency factor according to the minimum number of words that needs to be entered to cover each of the assessment terms, and calculating a coverage rate of each of the assessment terms according to the coverage efficiency factor and the prompt efficiency factor; and performing weighted averaging calculation on the coverage rate of each of the assessment terms, to obtain a coverage rate of the assessment target.

Abstract: The present disclosure discloses a terminal multiselection operation method and a terminal, which relate to the field of terminals and can implement a batch operation on multiple entries of displayed entries and increase an operation speed of a user. An embodiment of the present disclosure discloses a terminal multiselection operation method. The method includes receiving a first operation of a user when content currently displayed by a touchscreen is displayed entries. The displayed entries correspond to data items stored in a terminal. The method further includes activating the selection mode of the touchscreen when the first operation is a first preset operation for activating a selection mode. The method further includes receiving a second operation of the user and carrying out a second preset operation on all entries along a track of the second operation.

Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.

Abstract: The present application provides an information pushing method and apparatus. The method comprises: collecting a pushing parameter of each piece of information pushed in a time segment T, the pushing parameter comprising information pushing time, an information pushing user, or the number of times of the information being accessed; determining, according to the collected pushing parameter, an information access parameter of each user in the time segment T, the information access parameter comprises at least: the number of times of the information being visited in the time segment T, an information access tendency, and time of a last access of the information in T, and the information access tendency being determined by the number of times of the information being accessed; and selecting, according to the information access parameter of each user in the time segment T, a target user meeting a requirement, and pushing information to the target user.

Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.