Abstract: The present invention provides formulations for enhancing bioavailability of water-soluble compounds including water-soluble vitamins. The formulations include a water-soluble vitamin and a glycoside selected from a diterpene glycoside and a triterpene glycoside.

Abstract: The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu- A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.

Abstract: The present invention provides formulations for enhancing bioavailability of watersoluble compounds including water-soluble vitamins. The formulations include a watersoluble vitamin and a glycoside selected from a diterpene glycoside and a triterpene glycoside. Methods for increasing the bioavailability of a water-soluble vitamin are also described.

Abstract: An example method for facilitating hierarchical clustering in a geographically dispersed network environment is provided and includes receiving a packet at one of a plurality of adaptive security appliance (ASA) units in one of a plurality of ASA clusters in a cluster domain of a network environment, identifying the packet as matching an inter-data center live traffic profile, identifying a target ASA cluster in the plurality of ASA clusters in the cluster domain, querying a domain director in the target ASA cluster for a flow owner, and if the flow owner is identified by the domain director, forwarding the packet to the flow owner in the target cluster, and if the flow owner is not identified by the domain director, and the domain director includes a flow state for a flow to which the packet belongs, designating the ASA unit as the flow owner.

Abstract: A method and apparatus for different-frequency measurement and evaluation by a cluster answering user are provided, which relate to the technical field of communications. The method includes acquiring a public network signal evaluation threshold value and a signal threshold adjustment value, the signal threshold adjustment value being for adjusting an evaluation threshold; saving a result of different-frequency measurement by performing the different-frequency measurement on cells; and evaluating the saved result of different-frequency measurement using the acquired public network signal evaluation threshold value and the acquired signal threshold adjustment value. The method and apparatus enable a cluster terminal to timely measure a better adjacent cell and to switch to the cell, thereby making the cluster terminal always reside in a better cell to use voice and data services, ensuring the quality of the services and bringing user experience.

Abstract: Suspension polymerization toner of a core-shell structure with dense charges comprises core-shell composite particles prepared by mixing suspension dispersion liquid of toner core particles with shell monomer emulsion and resin-type CCA dispersion liquid, and carrying out a polymerization reaction to form rigid shell layers with dense charges coated on the soft toner core particles.

Abstract: Suspension polymerization toner of core-shell structure with positive charges comprises core-shell composite particles prepared by mixing composition forming toner core particles with aqueous dispersion liquid, carrying out a heating polymerization reaction to obtain suspension dispersion liquid of toner soft core particles, and carrying out a water-based polymerization reaction to form the core-shell composite particles of which an outer surface of the toner core particles are coated with the rigid shell layer with dense positive charges.

Abstract: A method for preparing suspension polymerization toner of core-shell structure comprises following steps: 1) preparing a monomer oil phase containing a certain amount of polar resin forming toner soft core resin and aqueous dispersion liquid respectively; 2) adding the monomer oil phase into the aqueous dispersion liquid, transferring a mixture into a reactor after high-speed shearing and suspension granulation, and carrying out a first heating polymerization reaction to obtain toner particles of soft-core hard-shell structure; 3) taking the toner particles of soft-core hard-shell structure as a core layer, adding a cationic monomer component, and carrying out a second polymerization reaction through a water-soluble initiator to obtain the toner particles of soft-core hard-shell structure with dense charge surface layers uniformly distributed on outer surfaces; and 4) cleaning, filtering, and sufficiently drying a preceding product, and then adding silicon dioxide.

Abstract: A cylinder liner with high strength and wear resistance and a manufacturing method thereof. The composition (% by mass) of the cylinder liner is as follows: C: 3.0-3.3%, Si: 2.0-2.3%, P: 0.3-0.6%, S: <0.1%, Mn: 0.3-0.6%, Mo: 0.1-0.3%, Nb: 0.08-0.15%, and the balance Fe. The structure of the cylinder liner is phosphorus-containing acicular ferrite and carbon-rich austenite, wherein the phosphide eutectic is no less than 3%. The cylinder liner has a hardness of HRC38-43, Rm>400 MPa, high strength and good wear resistance, solves the problem of pearlite cylinder liner with low wear resistance and cast bainite with bad corrosion resistance.

Abstract: Methods an apparatus are presented for identifying ground fault locations in multi-drive systems in which individual drives perform self-diagnosis for detected faults based on an identified fault signal frequency while the system drives continue operation, and a ground fault location system identifies suspected drives and individually confirms or exonerates individual drives by selective command speed adjustment while the drives remain operational within system tolerance ranges.

Abstract: The present techniques include methods and systems for detecting a high resistive ground fault condition in an HRG system. Embodiments include systems and methods of measuring drive voltages and detecting voltage changes in the drive once the drive is in operation, particularly for drives operating at relatively low voltages and frequencies. In some embodiments, an integrator is utilized to detect peaks in the measured voltage changes. Relatively small ground currents are also measured to determine HRG faults. Moreover, in some embodiments, the detection of an HRG fault for one of several motor drives provide indication for the particular motor drive in fault.

Abstract: The present invention is directed to methods for extracting and isolating extracts having angiogenesis inhibiting activity from a latex-containing portion of a Ficus variant, pharmaceutical and nutraceutical compositions comprising the extracts, methods of administering the extracts to treat angiogenesis-dependent diseases and to reduce or inhibit neovessel growth in a subject in need thereof and the use of the extracts in the manufacture of a composition for reducing or inhibiting neovessel growth.

Abstract: The combination of gallic acid, ellagic acid, and rubusoside was shown to inhibit angiogenesis by inhibition of pro-angiogenic factors. These three compounds were shown to be absorbed from the intestine making the compounds orally bioavailable. The ratio of the three compounds in the composition was a weight ratio of approximately 1:1.7:17.0 of gallic acid, ellagic acid, and rubusoside, respectively, resulting in a composition with 5% w/w gallic acid, 9% w/w ellagic acid, and 86% w/w rubusoside. This combination was also shown to reduce weight gain, fat accumulation, and serum cholesterol in mammals fed a high fat diet. It also reduced serum triglycerides and tended to reduce blood glucose in mammals on both normal and high fat diets. This three-compound composition (“GER”) can be used to treat diseases associated with angiogenesis and to decrease effects of a high fat diet.

Abstract: The present invention is directed to methods for extracting and isolating extracts having angiogenesis inhibiting activity from a latex-containing portion of a Ficus variant, pharmaceutical and nutraceutical compositions comprising the extracts, methods of administering the extracts to treat angiogenesis-dependent diseases and to reduce or inhibit neovessel growth in a subject in need thereof, and the use of the extracts in the manufacture of a composition for reducing or inhibiting neovessel growth.

Abstract: A conical solid-liquid separator includes a separator body, a clean water collection tank and a wastewater collection tank provided at an upper surface of the separator body, a conical sieves provided at the top of the clean water collection tank, an arc cone sheathed on the top of the conical sieves and having an upper end connected an inlet pipe. With the installation of the conical sieves, wastewater flows from the inlet pipe into the arc cone and then passes through the arc cone to disperse the water flow and enters into the conical sieves for filtering. The conical solid-liquid separator and its operating process are simplified to reduce water consumption and improve the processing efficiency. In addition, the conical solid-liquid separator comes with a simple and compact structure and reduces the power consumption significantly.

Abstract: A jet array aeration apparatus includes a pump, an inlet pipe, an air inlet duct and an outlet pipe installed sequentially. The air inlet duct is a multi-way duct containing an aeration structure which includes a jet ring and a ring-shaped air inlet space formed between the outer wall of the jet ring and the inner wall of the air inlet duct and interconnected to the outlet pipe. The jet ring has plural array via holes for dividing a circular water column flowing through the jet ring into gear-shaped water columns and forming an array vacuum negative-pressure area, so that a large amount of air may be sucked through the air inlet duct to form a large quantity of air bubbles, so as to achieve the aeration effect.

Abstract: Sweet gum (Liquidambar styraciflua L., family Hamamelidaceae) fruit extract was discovered to possess potent activities against multiple targets of the PI3K (phosphatidylinositide 3-kinase) pathway, especially the PI3K/Akt and mTOR pathways. At a very low concentration of 1.85 ?g/ml (IC50), sweet gun extract showed the ability of simultaneously blocking the pathways of PI3K/Akt (upstream), mTOR (mammalian target of rapamycin) (downstream), as well as its downstream protein products S6K and S6. It was also able to block 5-HETE, a lipoxygenase product that contributes to inflammation and activation of PI3K/Akt. The sweet gum fruit extract was prepared with 50% methanol (47:1; raw to extract) and concentrated to an organic fraction (210:1 raw to extract) referred as LIS-100 via reverse-phase column chromatography using a bioassay directed fractionation approach.

Abstract: A PLC or other industrial controller programmed to locate ground faults in a networked high resistance grounded multi-drive system through network communications messaging to automatically place networked motor drives in various operational states to isolate individual drives for ground fault identification testing and selectively identify individual drives as suspected ground fault locations.

Abstract: An automatic feeding apparatus includes a reaction container, and two or more dosing containers installed above the reaction container and having a feeding end extending into the reaction container. The reaction container has a water inlet formed on a sidewall of the reaction container and a siphon draining device installed at the bottom of the reaction container for discharging a liquid from the reaction container to the outside. The reaction container includes a mixer that divides the reaction container into an upper-layer reaction area and a lower-layer reaction area. Therefore, a liquid and/or a powder in the dosing container flows into the mixer, and then flows into water through the lower-layer reaction area and the water inlet for dilution. If the water level of the lower-layer reaction area exceeds the siphon level, the mixed liquid will be discharged out of the reaction container by the siphon effect.

Abstract: An automatic material adder includes a reaction container, a feed storage tank, installed at the top of the reaction container; and at least one liquid bottle, installed adjacent to the feed storage tank, and having a feeding end and a liquid transfer end of the liquid bottle directly or indirectly interconnected with the interior of the reaction container, and the feeding end of the feed storage tank further having an automatic switching device for feeding a material at a fixed time, and the reaction container having a water inlet formed on a sidewall of the reaction container, and a siphon draining device installed on the bottom wall of the reaction container for discharging a mixture contained in the reaction container to the outside.