Patents by Inventor Zhilei YUE

Zhilei YUE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230331772
    Abstract: The present invention provides a method for purification of a recombinant protein, in particular to a recombinant human albumin; the method includes: (a) adding aminoguanidine and a medium-long chain fatty acid to a sample containing the recombinant protein; and (b) chromatographing the obtained sample, where the chromatography is optionally performed with a chromatographic buffer solution containing aminoguanidine.
    Type: Application
    Filed: December 8, 2020
    Publication date: October 19, 2023
    Applicant: TONGHUA ANRATE BIOPHARMACEUTICAL CO., LTD
    Inventors: Wei XIANG, Zhilei YUE, Hongzhi Zhao, Congwei Shao
  • Publication number: 20220313790
    Abstract: A preparation method of a human albumin-containing medical product comprises controlling a content of long-chain fatty acids in the medical product and adding poloxamer to the medical product. The long-chain fatty acid is one or more selected from myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid and arachidonic acid, and a molar ratio of the long-chain fatty acids and human albumin is 0.2-3.0. A content of the poloxamer is 10-500 ?g/g of human albumin. The human albumin-containing medical product prepared by the method has improved stability and does not contain particle of over 30 nm in diameter is formed from aggregation and/or fibrillation of human albumin.
    Type: Application
    Filed: April 22, 2020
    Publication date: October 6, 2022
    Applicant: TONGHUA ANRATE BIOPHARMACEUTICAL CO., LTD
    Inventors: Wei XIANG, Zhilei YUE