Patents by Inventor Zhilian Tang

Zhilian Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted isoquinoline-1,3(2,4)-diones, 1-thioxo,1,4-dihydro-2-isoquinoline-3-ones and 1,4-dihyro-3 (2)-isoquinolones and methods of use thereof
    Patent number: 7713994
    Abstract: This invention provides compounds of Formula (I), having the structure where G1, G2, G3, G4, A1, A2, Y1, Y2, L1, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: May 11, 2010
    Assignee: Wyeth LLC
    Inventors: Hwei-Ru Tsou, Semiramis Ayral-Kaloustian, Gary Harold Birnberg, Middleton Brawner Floyd, Joshua Kaplan, Kristina M. Kutterer, Xiaoxiang Liu, Ramaswamy Nilakantan, Mercy Adufa Otteng, Zhilian Tang, Arie Zask, Tritin Tran, Scott Christian Mayer, Annette L. Banker, Marvin Reich
  • Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof
    Publication number: 20080085890
    Abstract: This invention provides compounds of Formula (I), having the structure where G1, G2, G3, G4, A1, A2, Y1, Y2, L1, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.
    Type: Application
    Filed: March 26, 2007
    Publication date: April 10, 2008
    Applicant: Wyeth
    Inventors: Hwei-Ru Tsou, Semiramis Ayral-Kaloustian, Gary Birnberg, Middleton Floyd, Joshua Kaplan, Kristina Kutterer, Xiaoxiang Liu, Ramaswamy Nilakantan, Mercy Otteng, Zhilian Tang, Arie Zask, Tritin Tran, Scott Mayer, Annette Banker, Marvin Reich
  • 2,4,6-trisubstituted pyridines with estrogenic activity and methods for the solid phase synthesis thereof
    Patent number: 6503917
    Abstract: The present invention relates to novel substituted pyridine compounds of Formula (I) wherein the moiety Z, R1, R2 and R3 are as herein defined, having estrogenic activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, to methods of treatment and to pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: January 7, 2003
    Assignee: Wyeth, Five Giralda Farms
    Inventors: Chingfan Chiu, Zhilian Tang, John W. Ellingboe
  • 2,4,6-trisbstituted pyridines with estrogenic activity and methods for the solid phase synthesis thereof
    Patent number: 6384060
    Abstract: The present invention relates to novel substituted pyridine compounds of Formula (I) wherein the moiety Z, R1, R2 and R3 are as herein defined, having estrogenic activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, to methods of treatment and to pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: May 7, 2002
    Assignee: American Home Products Corporation
    Inventors: Chingfan Chiu, Zhilian Tang, John W. Ellingboe
  • 2,4,6-trisubstituted pyridines with estrogenic activity and methods for the solid phase synthesis
    Patent number: 6384057
    Abstract: The present invention relates to novel substituted pyridine compounds of Formula (I) wherein the moiety Z, R1, R2 and R3 are as herein defined, having estrogenic activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, to methods of treatment and to pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: May 7, 2002
    Assignee: American Home Products Corporation
    Inventors: Chingfan Chiu, Zhilian Tang, John W. Ellingboe
  • 2,4,6-trisubstituted pryridines with estrogenic activity and methods for the solid phase synthesis thereof
    Patent number: 6384058
    Abstract: The present invention relates to novel substituted pyridine compounds of Formula (I) wherein the moiety Z, R1, R2 and R3 are as herein defined, having estrogenic activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, to methods of treatment and to pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: May 7, 2002
    Assignee: American Home Products Corporation
    Inventors: Chingfan Chiu, Zhilian Tang, John W. Ellingboe