Patents by Inventor Zhilong MA

Zhilong MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoisothiazole compounds and methods of treating schizophrenia
    Patent number: 9550741
    Abstract: Disclosed are benzoisothiazole compounds and a use in the preparation of anti-schizophrenia drugs. The benzoisothiazole compounds of the present invention not only have strong affinity for dopamine D3 receptor, 5-HT1A receptor and 5-HT2A receptor, but also can observably improve the symptoms of schizophrenia relevant to apomorphine model and MK-801 model mice, with oral absorption being good, safety being high and side-effect being less, and having developmental value as new anti-neurotic disease drugs. The present invention is the compounds having a structure of general formula (I), or geometric isomers, free alkalies, salts, hydrates or solvates thereof.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: January 24, 2017
    Assignee: Shanghai Institute of Pharmaceutical Industry
    Inventors: Jianqi Li, Xiaowen Chen, Zhilong Ma, Li Zhang, Ning Cui
  • BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS
    Publication number: 20160096811
    Abstract: Disclosed are benzoisothiazole compounds and a use in the preparation of anti-schizophrenia drugs. The benzoisothiazole compounds of the present invention not only have strong affinity for dopamine D3 receptor, 5-HT1A receptor and 5-HT2A receptor, but also can observably improve the symptoms of schizophrenia relevant to apomorphine model and MK-801 model mice, with oral absorption being good, safety being high and side-effect being less, and having developmental value as new anti-neurotic disease drugs. The present invention is the compounds having a structure of general formula (I), or geometric isomers, free alkalies, salts, hydrates or solvates thereof.
    Type: Application
    Filed: May 8, 2014
    Publication date: April 7, 2016
    Applicant: SHANAGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
    Inventors: Jianqi LI, Xiaowen CHEN, Zhilong MA, Li ZHANG, Ning CUI