Abstract: A heat exchange device includes a heat exchanger and a water guider. The water guider is arranged on the heat exchanger and has a water guide groove, and condensed water on at least a part of the heat exchanger can flow out through the water guide groove. The heat exchange device has a good drainage performance, can prevent the condensed water from accumulating, and thus improves a heat exchange area and a heat exchange efficiency of the heat exchanger.

Abstract: A heat exchange apparatus includes a heat exchanger, a refrigerant adjustment component, and a first connecting member. The heat exchanger includes a first pipe, a second pipe, a plurality of heat exchange tubes connecting the first pipe and the second pipe, and an edge plate located on an outer side of the plurality of heat exchange tubes in a length direction of the first pipe. At least part of the refrigerant adjustment component is located on an outer side of the edge plate in the length direction of the first pipe. An included angle between an axis in a length direction of at least part of an outer wall of the refrigerant adjustment component and an axis in the length direction of the first pipe is greater than 0° and less than or equal to 90°.

Abstract: A heat exchange device includes a heat exchanger and a water guider. The water guider is arranged on the heat exchanger and has a water guide groove, and condensed water on at least a part of the heat exchanger can flow out through the water guide groove. The heat exchange device has a good drainage performance, can prevent the condensed water from accumulating, and thus improves a heat exchange area and a heat exchange efficiency of the heat exchanger.

Abstract: A fin and a bending type heat exchanger having the fin includes a first header pipe, a second header pipe, a flat pipe and the fin. The first header pipe and the second header pipe have bending sections. The fin extends generally in a wavy shape along a longitudinal direction and includes a main section and a connecting section, the main section and the connecting section are connected in series so as to make the connecting section form a wave crest and a wave trough, and the fin is divided into a first end portion, a second end portion, and a central portion between the first end portion and the second end portion along a transverse direction, in which the connecting section of the central portion, forming the wave crest and the wave trough, is connected with the flat pipe, and a gap exists between the connecting section, forming the wave crest and/or the wave trough, of at least one of the first end portion and the second end portion and the flat pipe within the bending section.

Abstract: A fin and a bending type heat exchanger having the fin includes a first header pipe, a second header pipe, a flat pipe and the fin. The first header pipe and the second header pipe have bending sections. The fin extends generally in a wavy shape along a longitudinal direction and includes a main section and a connecting section, the main section and the connecting section are connected in series so as to make the connecting section form a wave crest and a wave trough, and the fin is divided into a first end portion, a second end portion, and a central portion between the first end portion and the second end portion along a transverse direction, in which the connecting section of the central portion, forming the wave crest and the wave trough, is connected with the flat pipe, and a gap exists between the connecting section, forming the wave crest and/or the wave trough, of at least one of the first end portion and the second end portion and the flat pipe within the bending section.

Abstract: The present invention provides methods for preparing 5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-2-pyridinamine (compound A), which is useful for the treatment of depression and other CNS disorders. The present methods are useful for preparing compound A on large scale in manufacturing facilities.

Abstract: The present invention provides novel methods for preparing N—(S)-1 -azabicyclo[2.2.2]oct-3-yl-1H-indazole-3-carboxamide HCl salt 1, a nicotinic ?-7 receptor ligand, that are useful for the scaled-up preparation of compound 1. Compound 1 is useful in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders.

Abstract: The present invention provides novel methods for preparing N—(S)-1-azabicyclo[2.2.2]oct-3-yl-1H-indazole-3-carboxamide HCl salt 1, a nicotinic ?-7 receptor ligand, that are useful for the scaled-up preparation of compound 1. Compound 1 is useful in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders.

Abstract: A method of converting pure ?-anomer or ?/?-anomer mixtures of 1,2,3,5-tetra-O-acetyl-L-ribofuranose to methyl-1-(2,3,5-tri-O-acetyl-?-L-ribofuranosyl)-1,2,4-triazole-3-carboxylate an intermediate for levovirin, as well as, the novel pure ?-anomer, alpha 1,2,3,5-tetra-O-acetyl-L-ribofuiranose, are useful in manufacturing levovirin.

Abstract: A method of converting pure &agr;-anomer or &bgr;/&agr;-anomer mixtures of 1,2,3,5-tetra-O-acetyl-L-ribofuranose to methyl-1-(2,3,5 -tri-O-acetyl-&bgr;-L-ribofuranosyl)-1,2,4-triazole-3-carboxylate an intermediate for levovirin, as well as, the novel pure &agr;-anomer, alpha 1,2,3,5-tetra-O-acetyl-L-ribofuiranose, are useful in manufacturing levovirin.