Patents by Inventor Zhiming Suo

Zhiming Suo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting and preventing Alzheimer's disease, particularly at prodromal and early stages
    Patent number: 7252953
    Abstract: A method of detecting Alzheimer's disease includes detecting a disruption or alteration in normal sub-cellular distribution of G-protein receptor kinases (GRKs), particularly GRK2 and GRK5. The disruption is caused by abnormal accumulation of soluble ?-amyloid. The prevention or suppression of the disease progression at prodromal or early stages includes correction of GRK dysfunction.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: August 7, 2007
    Assignee: United States of America Department of Veterans Affairs
    Inventors: Zhiming Suo, Barry W. Festoff
  • Method of detecting and preventing alzheimer's disease, particularly at prodromal and early stages
    Publication number: 20050272025
    Abstract: A method of detecting Alzheimer's disease includes detecting a disruption or alteration in normal sub-cellular distribution of G-protein receptor kinases (GRKs), particularly GRK2 and GRK5. The disruption is caused by abnormal accumulation of soluble ?-amyloid. The prevention or suppression of the disease progression at prodromal or early stages includes correction of GRK dysfunction.
    Type: Application
    Filed: August 12, 2003
    Publication date: December 8, 2005
    Inventors: Zhiming Suo, Barry Festoff
  • Vasoactive effects and free radical generation by .beta.-amyloid peptides
    Patent number: 6011019
    Abstract: A method is disclosed for treating and preventing diseases, wherein at least one of the causes of the disease is .beta.-amyloid peptide induced change in free radical production resulting in vascular endothelial dysfunction and vasoactivity, by antagonizing vascular free radicals in excess of functional equilibrium. An animal model for the disease is also disclosed.
    Type: Grant
    Filed: November 12, 1996
    Date of Patent: January 4, 2000
    Assignee: University of South Florida
    Inventors: Thomas N. Thomas, Michael Mullan, Gary W. Arendash, Fiona C. Crawford, Zhiming Suo