Abstract: The present invention relates to a bioactive polypeptide synthesized on the basis of histone demethylase, and the use thereof in the neural differentiation process of mesenchymal stem cells. Disclosed in the present invention are possible protein-protein interaction binding sites of histone demethylase KDM2B and histone methylate EZH2, and disclosed are the roles of KDM2B and the bioactive polypeptide synthesized on the basis of the same in the neural differentiation process of mesenchymal stem cells and the tissue regeneration of injured spinal nerves. On this basis, it is concluded that KDM2B and the bioactive polypeptide synthesized on the basis of the same may play a role in promoting the neural differentiation of stem cells from apical papilla and the regeneration of injured spinal nerves.

Abstract: The application describes method of modifying an image. The method may include a step of receiving, via an user interface of a service, a reference image and an input including text associated with the reference image. The method may also include a step of determining, via a trained machine learning (ML) model, one or more features of the reference image. The method may further include a step of modifying, via one or more trained latent diffusion models (LDMs), the reference image based upon the determined features and the received input. Any one or more of a background of the reference image, an area of the reference image or a style of the reference image may be modified. The method may even further include a step of causing to display, via the user interface of the service, the modified image.

Abstract: Disclosed in the present invention is an application of lysine (K)-specific demethylase 6B (KDM6B) in regulating and controlling the function of a mesenchymal stem cell. WDR5 is a co-binding protein for negatively regulating and controlling the functions of KDM6B and the MLL1. WDR5 can form a protein complex with KDM6B to inhibit the function of KDM6B, such that expression and functions of genes are regulated and controlled by regulating and controlling the methylation state of downstream senescence and osteogenesis related genes and gene promoter region histone, and finally the effects of regulating stem cell senescence and differentiation functions and bone/tooth tissue repair and regeneration functions are achieved. For a KDM6B and WDR5 binding region sequence, small-molecule polypeptide is researched, developed, and utilized, and the function of the mesenchymal stem cell is regulated by regulating and controlling the binding of a KDM6B/WDR5 complex.

Abstract: An electronic device for object rigging includes a processor. The processor is configured to obtain a three-dimensional (3D) scan of an object. The processor is also configured to identify 3D coordinates associated with joints of the 3D scan. The processor is further configured to identify parameters associated with fitting a 3D parametric body model to the 3D scan based on the 3D coordinates of the joints. Additionally, the processor is configured to modify the parameters to reduce 3D joint errors between the 3D coordinates associated with the joints on the 3D scan and the 3D parametric body model. The processor is also configured to generate a rigged 3D scan based on the modified parameters, for performing an animated motion.

Abstract: An electronic device for object rigging includes a processor. The processor is configured to obtain a three-dimensional (3D) scan of an object. The processor is also configured to identify 3D coordinates associated with joints of the 3D scan. The processor is further configured to identify parameters associated with fitting a 3D parametric body model to the 3D scan based on the 3D coordinates of the joints. Additionally, the processor is configured to modify the parameters to reduce 3D joint errors between the 3D coordinates associated with the joints on the 3D scan and the 3D parametric body model. The processor is also configured to generate a rigged 3D scan based on the modified parameters, for performing an animated motion.