Patents by Inventor Zhiqian Li
Zhiqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124880Abstract: The invention provides a diagnostic kit for metastasis and invasion of breast cancer and a use of an shRNA molecule for silencing expression of human LINC01614. The shRNAs obtained by the invention can interfere with the expression of LINC01614, thereby reducing the migration and invasion ability of tumor cells, inhibiting the expression of EMT proteins, and inhibiting tumor formation and lung metastasis in an animal model in vivo. The invention provides a new solution for targeted therapy of breast cancer. Therefore, the kit for diagnosing metastasis and invasion of breast cancer and the medication for treating metastasis and invasion of breast cancer are developed. The invention provides a new way and strategy for diagnosing and treating metastasis and invasion of breast cancer.Type: ApplicationFiled: November 29, 2023Publication date: April 18, 2024Applicant: Zhejiang Chinese Medical UniversityInventors: Fangfang TAO, Zhiqian ZHANG, Wenhong LIU, Ye XU, Qingling LIU, Junfeng LI
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Publication number: 20220325338Abstract: Provided herein are systems and methods for performing repair of mutant chromosomes in cells by using the homologous chromosome as a template for homology directed repair. Also provided herein are CopyCatcher systems, methods, and organisms for the study and measurement of homologous chromosome template repair and related mechanisms in cells and organisms.Type: ApplicationFiled: April 1, 2022Publication date: October 13, 2022Inventors: Ethan Bier, Annabel Guichard, Zhiqian Li
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Patent number: 10742223Abstract: A method and device for calibrating an RC oscillator, a storage medium and a processor are provided. The method may include: in a first communication time period, a frequency of a first RC oscillator is adjusted at a first communication frequency point; at the first communication frequency point, the frequency of the first RC oscillator is adjusted according to a default gear of the first RC oscillator sequentially, and at least one of a corresponding gear value and a corresponding frequency when the first device end may receive or may not receive data sent by a second device end is recorded; a first target frequency and a first target gear value of the first RC oscillator are determined according to the at least one of a corresponding gear value and a corresponding frequency; and the first device end is controlled to communicate with the second device end at a second communication frequency point which is determined by the first target gear value in a second communication time period.Type: GrantFiled: November 13, 2018Date of Patent: August 11, 2020Assignee: BEIJING SIGMA MICROELECTRONICS CO., LTDInventors: Zhiqian Li, Zhixun Yang
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Patent number: 10596452Abstract: Disclosed is a toy interactive method and device. The method comprises: a medium sample is collected and reference sample information of the medium sample is generated; a playing content of a medium being played is collected; characteristic information of the collected playing content is extracted; the extracted characteristic information is matched with the reference sample information to obtain a matching result; according to the obtained matching result, a to-be-played content that is to be played after a predetermined time period in the medium being played is predicted; and according to the predicted to-be-played content, a toy is driven to synchronously execute an interactive content corresponding to the to-be-played content at a corresponding time point after the predetermined time period. Through the toy interactive method and device, the technical problem is solved.Type: GrantFiled: November 30, 2017Date of Patent: March 24, 2020Assignee: Shenzhen Sigma Microelectronics Co., Ltd.Inventors: Zhenquan Chu, Zhiqian Li
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Publication number: 20190149156Abstract: A method and device for calibrating an RC oscillator, a storage medium and a processor are provided. The method may include: in a first communication time period, a frequency of a first RC oscillator is adjusted at a first communication frequency point; at the first communication frequency point, the frequency of the first RC oscillator is adjusted according to a default gear of the first RC oscillator sequentially, and at least one of a corresponding gear value and a corresponding frequency when the first device end may receive or may not receive data sent by a second device end is recorded; a first target frequency and a first target gear value of the first RC oscillator are determined according to the at least one of a corresponding gear value and a corresponding frequency; and the first device end is controlled to communicate with the second device end at a second communication frequency point which is determined by the first target gear value in a second communication time period.Type: ApplicationFiled: November 13, 2018Publication date: May 16, 2019Inventors: Zhiqian Li, Zhixun Yang
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Publication number: 20190099666Abstract: Disclosed is a toy interactive method and device. The method comprises: a medium sample is collected and reference sample information of the medium sample is generated; a playing content of a medium being played is collected; characteristic information of the collected playing content is extracted; the extracted characteristic information is matched with the reference sample information to obtain a matching result; according to the obtained matching result, a to-be-played content that is to be played after a predetermined time period in the medium being played is predicted; and according to the predicted to-be-played content, a toy is driven to synchronously execute an interactive content corresponding to the to-be-played content at a corresponding time point after the predetermined time period. Through the toy interactive method and device, the technical problem is solved.Type: ApplicationFiled: November 30, 2017Publication date: April 4, 2019Inventors: Zhenquan CHU, Zhiqian LI
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Patent number: 10159281Abstract: The present disclosure claims an electronic cigarette, a cigarette rod, a cigarette cartridge, and a recognition method of a cigarette cartridge, wherein the electronic cigarette includes: the cigarette rod and the cigarette cartridge. The cigarette rod includes: a battery and a controller, and the cigarette cartridge includes: an atomizer and a recognition information provider component connected with the atomizer, wherein the atomizer is connected with the controller via the recognition information provider component, wherein the recognition information provider component is configured to send recognition information to the controller, and the controller is configured to judge whether the cigarette rod and the cigarette cartridge are matched, and if so, allow the atomizer to work normally. Otherwise, the controller executes alarming or prohibits the atomizer from working normally.Type: GrantFiled: July 5, 2016Date of Patent: December 25, 2018Assignee: Beijing Sigma Microelectronics Co., LtdInventor: Zhiqian Li
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Publication number: 20180323633Abstract: The disclosure discloses a reception device for wireless charging and terminal device. The reception device for wireless charging includes: a coupling coil, arranged to acquire an alternating current signal; a rectifier tube, connected with the coupling coil and arranged to rectify the alternating current signal to obtain a charging current signal, wherein the charging current signal is used to charge a module to be charged; and a first Metal Oxide Semiconductor (MOS) transistor, connected with the rectifier tube and arranged to control switching-on or switching-off of a circuit between the rectifier tube and the module to be charged according to a coding value and transmit coding information corresponding to an on/off state of the circuit to a transmitter. According to the disclosure, the technical problem of complex circuit structure caused by full-bridge rectification adopted by a reception device for wireless charging in the related technology is solved.Type: ApplicationFiled: September 5, 2017Publication date: November 8, 2018Inventors: Bingjie CHEN, Zhiqian LI
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Publication number: 20170000192Abstract: The present disclosure claims an electronic cigarette, a cigarette rod, a cigarette cartridge, and a recognition method of a cigarette cartridge, wherein the electronic cigarette includes: the cigarette rod and the cigarette cartridge. The cigarette rod includes: a battery and a controller, and the cigarette cartridge includes: an atomizer and a recognition information provider component connected with the atomizer, wherein the atomizer is connected with the controller via the recognition information provider component, wherein the recognition information provider component is configured to send recognition information to the controller, and the controller is configured to judge whether the cigarette rod and the cigarette cartridge are matched, and if so, allow the atomizer to work normally. Otherwise, the controller executes alarming or prohibits the atomizer from working normally.Type: ApplicationFiled: July 5, 2016Publication date: January 5, 2017Inventor: Zhiqian LI
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Patent number: 9104942Abstract: This invention, which relates to retrieving an object from a video or a photo where the object matches a hand-drawn sketch, discloses a method for automatically estimating a perceptual bias level with respect to a feature of the sketch. The method allows estimation based on the sketch alone without involving an extra database. In one embodiment, the method comprises using an expectation-maximization tensor voting (EMTV) method to analyze a statistical distribution of the feature. The statistical distribution is analyzed by forming an objective function having the statistical distribution's information parameterized by the perceptual bias level, and then maximizing the objective function according to a set of iterative update rules. In another embodiment, the method for automatically estimating a perceptual bias level is incorporated into a method for retrieving one or more objects from an image or video database where the one or more objects match a hand-drawn sketch.Type: GrantFiled: December 19, 2012Date of Patent: August 11, 2015Assignee: Hong Kong Applied Science and Technology Research Institute Company LimitedInventors: Tai Pang Wu, Zhiqian Li, Kenneth Kwan Yee Wong
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Patent number: 9013406Abstract: The disclosure discloses a mouse key identification circuit, a mouse key identification device and a mouse. The mouse key identification circuit comprises: N keys, M collection ports, a Light-Emitting Diode (LED) driver circuit and a grounding terminal, wherein part or all of i keys in N keys are connected to the LED port of the LED driver circuit by one respective end, while the other end of the i keys is connected to i collection ports of the M collection ports respectively, wherein i is less than N and N is a natural number; the grounding terminal is connected to one respective end of N?i keys of the N keys, and the other end of the N?i keys is connected to N?i collection ports of the M collection ports respectively. With the disclosure, the number of signal collection ports can be reduced and the cost of a mouse can be lowered.Type: GrantFiled: September 3, 2012Date of Patent: April 21, 2015Assignee: Beijing Sigmachip Co. LtInventors: Zhiqian Li, Lun Lv, Yongqing Yan
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Patent number: 8719687Abstract: A computer-implementable method for creating a summary video with depth information, comprising: recognizing moving objects from the input original video; generating an animated moving object cutout for each of the recognized moving objects by duplicating and stacking successive frames in the input original video containing images of the respective moving object; constructing a scene background by using texture of scenes in the input original video and estimating any missing portion; rendering a Dynamic 3D Scene by using depth information of foreground objects in the input original video and the scene background to create a three-dimensional scene and overlaying the animated moving object cutouts on to the three-dimensional scene according to their respective longitude, latitude, and depth locations in the three-dimensional scene; and synthesizing the summary video, by using the Dynamic 3D Scene.Type: GrantFiled: December 23, 2011Date of Patent: May 6, 2014Assignee: Hong Kong Applied Science and Technology ResearchInventors: Tai Pang Wu, Zhiqian Li, Xiao Zhou, Chun Man Lawrence Mak
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Publication number: 20130163961Abstract: A computer-implementable method for creating a summary video with depth information, comprising: recognizing moving objects from the input original video; generating an animated moving object cutout for each of the recognized moving objects by duplicating and stacking successive frames in the input original video containing images of the respective moving object; constructing a scene background by using texture of scenes in the input original video and estimating any missing portion; rendering a Dynamic 3D Scene by using depth information of foreground objects in the input original video and the scene background to create a three-dimensional scene and overlaying the animated moving object cutouts on to the three-dimensional scene according to their respective longitude, latitude, and depth locations in the three-dimensional scene; and synthesizing the summary video, by using the Dynamic 3D Scene.Type: ApplicationFiled: December 23, 2011Publication date: June 27, 2013Applicant: Hong Kong Applied Science and Technology Research Institute Company LimitedInventors: Tai Pang Wu, Zhiqian Li, Xiao Zhou, Chun Man Lawrence Mak
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Publication number: 20130057474Abstract: The disclosure discloses a mouse key identification circuit, a mouse key identification device and a mouse. The mouse key identification circuit comprises: N keys, M collection ports, a Light-Emitting Diode (LED) driver circuit and a grounding terminal, wherein part or all of i keys in N keys are connected to the LED port of the LED driver circuit by one respective end, while the other end of the i keys is connected to i collection ports of the M collection ports respectively, wherein i is less than N and N is a natural number; the grounding terminal is connected to one respective end of N?i keys of the N keys, and the other end of the N?i keys is connected to N?i collection ports of the M collection ports respectively. With the disclosure, the number of signal collection ports can be reduced and the cost of a mouse can be lowered.Type: ApplicationFiled: September 3, 2012Publication date: March 7, 2013Applicant: BEIJING SIGMACHIP CO. LTDInventors: Zhiqian LI, Lun LV, Yongqing YAN
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Patent number: 8077925Abstract: The present invention discloses a method for motion sensing of sub-pixel level precision. The method comprises the following steps: acquiring a reference image (reference frame) and a sample image (sample frame) of a surface; calculating the correlation between the reference frame and the sample frame to obtain a motion vector of a photoelectric mouse with respect to this surface; subjecting the reference frame and the sample frame to interpolation to obtain the interpolated reference frame and the interpolated sample frame; calculating the correlation between the interpolated reference frame and the interpolated sample frame in order to correct the aforesaid motion vector and to obtain the movement of the sub-pixel. The precision of displacement measurement can be improved effectively by this method under the condition that sensor's characteristics are not changed to improve the performance of the photoelectric mouse.Type: GrantFiled: November 17, 2008Date of Patent: December 13, 2011Assignee: Beijing Sigmachip Co., LtdInventors: Yongqing Yan, Zhiqian Li
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Publication number: 20090324019Abstract: The present invention discloses a method for motion sensing of sub-pixel level precision. The method comprises the following steps: acquiring a reference image (reference frame) and a sample image (sample frame) of a surface; calculating the correlation between the reference frame and the sample frame to obtain a motion vector of a photoelectric mouse with respect to this surface; subjecting the reference frame and the sample frame to interpolation to obtain the interpolated reference frame and the interpolated sample frame; calculating the correlation between the interpolated reference frame and the interpolated sample frame in order to correct the aforesaid motion vector and to obtain the movement of the sub-pixel. The precision of displacement measurement can be improved effectively by this method under the condition that sensor's characteristics are not changed to improve the performance of the photoelectric mouse.Type: ApplicationFiled: November 17, 2008Publication date: December 31, 2009Applicant: BEIJING SIGMACHIP CO., LTD.Inventors: Yongqing YAN, Zhiqian LI
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Patent number: 7598752Abstract: The disclosure relates to a touch sensing device and method. An embodiment of the disclosed method includes starting to count with a counter while charging a sensing point which has distributed capacitance periodically, then transferring the charge on the sensing point to a second capacitor. Next, the voltage on the second capacitor is compared with a reference voltage, and if the former exceeds the latter, the counter stops counting and saving the value. If the voltage on the second capacitor is less than the reference voltage, the sensing point is judged to determine whether it is in touching state or in non-touching state according to the saved count value while discharging the second capacitor, clearing the counter after the discharge, then restarting the method. Using the device and method of this disclosure, the touching sensing action can be tested accurately.Type: GrantFiled: December 29, 2006Date of Patent: October 6, 2009Assignee: Beijing, Sigmachip Co., Ltd.Inventor: Zhiqian Li
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Publication number: 20070247172Abstract: The disclosure relates to a touch sensing device and method. An embodiment of the disclosed method that comprises starting to count with a counter while charging a sensing point which has distributed capacitance periodically, then transferring the charge on the sensing point to a second capacitor. Next, the voltage on the second capacitor is compared with a reference voltage, and if the former exceeds the latter, the counter stops counting and saving the count value. If the voltage on the second capacitor is less than the reference voltage, the sensing point is judged to determine whether it is in a touching state or in a non-touching state according to the saved count value while discharging the second capacitor, clearing the counter after the discharge, then restarting the method. Using the device and method of this disclosure, the touching sensing action can be tested accurately.Type: ApplicationFiled: December 29, 2006Publication date: October 25, 2007Inventor: Zhiqian Li