Patents by Inventor Zhiqian Li

Zhiqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124880
    Abstract: The invention provides a diagnostic kit for metastasis and invasion of breast cancer and a use of an shRNA molecule for silencing expression of human LINC01614. The shRNAs obtained by the invention can interfere with the expression of LINC01614, thereby reducing the migration and invasion ability of tumor cells, inhibiting the expression of EMT proteins, and inhibiting tumor formation and lung metastasis in an animal model in vivo. The invention provides a new solution for targeted therapy of breast cancer. Therefore, the kit for diagnosing metastasis and invasion of breast cancer and the medication for treating metastasis and invasion of breast cancer are developed. The invention provides a new way and strategy for diagnosing and treating metastasis and invasion of breast cancer.
    Type: Application
    Filed: November 29, 2023
    Publication date: April 18, 2024
    Applicant: Zhejiang Chinese Medical University
    Inventors: Fangfang TAO, Zhiqian ZHANG, Wenhong LIU, Ye XU, Qingling LIU, Junfeng LI
  • Publication number: 20220325338
    Abstract: Provided herein are systems and methods for performing repair of mutant chromosomes in cells by using the homologous chromosome as a template for homology directed repair. Also provided herein are CopyCatcher systems, methods, and organisms for the study and measurement of homologous chromosome template repair and related mechanisms in cells and organisms.
    Type: Application
    Filed: April 1, 2022
    Publication date: October 13, 2022
    Inventors: Ethan Bier, Annabel Guichard, Zhiqian Li
  • Patent number: 10742223
    Abstract: A method and device for calibrating an RC oscillator, a storage medium and a processor are provided. The method may include: in a first communication time period, a frequency of a first RC oscillator is adjusted at a first communication frequency point; at the first communication frequency point, the frequency of the first RC oscillator is adjusted according to a default gear of the first RC oscillator sequentially, and at least one of a corresponding gear value and a corresponding frequency when the first device end may receive or may not receive data sent by a second device end is recorded; a first target frequency and a first target gear value of the first RC oscillator are determined according to the at least one of a corresponding gear value and a corresponding frequency; and the first device end is controlled to communicate with the second device end at a second communication frequency point which is determined by the first target gear value in a second communication time period.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: August 11, 2020
    Assignee: BEIJING SIGMA MICROELECTRONICS CO., LTD
    Inventors: Zhiqian Li, Zhixun Yang
  • Patent number: 10596452
    Abstract: Disclosed is a toy interactive method and device. The method comprises: a medium sample is collected and reference sample information of the medium sample is generated; a playing content of a medium being played is collected; characteristic information of the collected playing content is extracted; the extracted characteristic information is matched with the reference sample information to obtain a matching result; according to the obtained matching result, a to-be-played content that is to be played after a predetermined time period in the medium being played is predicted; and according to the predicted to-be-played content, a toy is driven to synchronously execute an interactive content corresponding to the to-be-played content at a corresponding time point after the predetermined time period. Through the toy interactive method and device, the technical problem is solved.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 24, 2020
    Assignee: Shenzhen Sigma Microelectronics Co., Ltd.
    Inventors: Zhenquan Chu, Zhiqian Li
  • Publication number: 20190149156
    Abstract: A method and device for calibrating an RC oscillator, a storage medium and a processor are provided. The method may include: in a first communication time period, a frequency of a first RC oscillator is adjusted at a first communication frequency point; at the first communication frequency point, the frequency of the first RC oscillator is adjusted according to a default gear of the first RC oscillator sequentially, and at least one of a corresponding gear value and a corresponding frequency when the first device end may receive or may not receive data sent by a second device end is recorded; a first target frequency and a first target gear value of the first RC oscillator are determined according to the at least one of a corresponding gear value and a corresponding frequency; and the first device end is controlled to communicate with the second device end at a second communication frequency point which is determined by the first target gear value in a second communication time period.
    Type: Application
    Filed: November 13, 2018
    Publication date: May 16, 2019
    Inventors: Zhiqian Li, Zhixun Yang
  • Publication number: 20190099666
    Abstract: Disclosed is a toy interactive method and device. The method comprises: a medium sample is collected and reference sample information of the medium sample is generated; a playing content of a medium being played is collected; characteristic information of the collected playing content is extracted; the extracted characteristic information is matched with the reference sample information to obtain a matching result; according to the obtained matching result, a to-be-played content that is to be played after a predetermined time period in the medium being played is predicted; and according to the predicted to-be-played content, a toy is driven to synchronously execute an interactive content corresponding to the to-be-played content at a corresponding time point after the predetermined time period. Through the toy interactive method and device, the technical problem is solved.
    Type: Application
    Filed: November 30, 2017
    Publication date: April 4, 2019
    Inventors: Zhenquan CHU, Zhiqian LI
  • Patent number: 10159281
    Abstract: The present disclosure claims an electronic cigarette, a cigarette rod, a cigarette cartridge, and a recognition method of a cigarette cartridge, wherein the electronic cigarette includes: the cigarette rod and the cigarette cartridge. The cigarette rod includes: a battery and a controller, and the cigarette cartridge includes: an atomizer and a recognition information provider component connected with the atomizer, wherein the atomizer is connected with the controller via the recognition information provider component, wherein the recognition information provider component is configured to send recognition information to the controller, and the controller is configured to judge whether the cigarette rod and the cigarette cartridge are matched, and if so, allow the atomizer to work normally. Otherwise, the controller executes alarming or prohibits the atomizer from working normally.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: December 25, 2018
    Assignee: Beijing Sigma Microelectronics Co., Ltd
    Inventor: Zhiqian Li
  • Publication number: 20180323633
    Abstract: The disclosure discloses a reception device for wireless charging and terminal device. The reception device for wireless charging includes: a coupling coil, arranged to acquire an alternating current signal; a rectifier tube, connected with the coupling coil and arranged to rectify the alternating current signal to obtain a charging current signal, wherein the charging current signal is used to charge a module to be charged; and a first Metal Oxide Semiconductor (MOS) transistor, connected with the rectifier tube and arranged to control switching-on or switching-off of a circuit between the rectifier tube and the module to be charged according to a coding value and transmit coding information corresponding to an on/off state of the circuit to a transmitter. According to the disclosure, the technical problem of complex circuit structure caused by full-bridge rectification adopted by a reception device for wireless charging in the related technology is solved.
    Type: Application
    Filed: September 5, 2017
    Publication date: November 8, 2018
    Inventors: Bingjie CHEN, Zhiqian LI
  • Publication number: 20170000192
    Abstract: The present disclosure claims an electronic cigarette, a cigarette rod, a cigarette cartridge, and a recognition method of a cigarette cartridge, wherein the electronic cigarette includes: the cigarette rod and the cigarette cartridge. The cigarette rod includes: a battery and a controller, and the cigarette cartridge includes: an atomizer and a recognition information provider component connected with the atomizer, wherein the atomizer is connected with the controller via the recognition information provider component, wherein the recognition information provider component is configured to send recognition information to the controller, and the controller is configured to judge whether the cigarette rod and the cigarette cartridge are matched, and if so, allow the atomizer to work normally. Otherwise, the controller executes alarming or prohibits the atomizer from working normally.
    Type: Application
    Filed: July 5, 2016
    Publication date: January 5, 2017
    Inventor: Zhiqian LI
  • Patent number: 9104942
    Abstract: This invention, which relates to retrieving an object from a video or a photo where the object matches a hand-drawn sketch, discloses a method for automatically estimating a perceptual bias level with respect to a feature of the sketch. The method allows estimation based on the sketch alone without involving an extra database. In one embodiment, the method comprises using an expectation-maximization tensor voting (EMTV) method to analyze a statistical distribution of the feature. The statistical distribution is analyzed by forming an objective function having the statistical distribution's information parameterized by the perceptual bias level, and then maximizing the objective function according to a set of iterative update rules. In another embodiment, the method for automatically estimating a perceptual bias level is incorporated into a method for retrieving one or more objects from an image or video database where the one or more objects match a hand-drawn sketch.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: August 11, 2015
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Tai Pang Wu, Zhiqian Li, Kenneth Kwan Yee Wong
  • Patent number: 9013406
    Abstract: The disclosure discloses a mouse key identification circuit, a mouse key identification device and a mouse. The mouse key identification circuit comprises: N keys, M collection ports, a Light-Emitting Diode (LED) driver circuit and a grounding terminal, wherein part or all of i keys in N keys are connected to the LED port of the LED driver circuit by one respective end, while the other end of the i keys is connected to i collection ports of the M collection ports respectively, wherein i is less than N and N is a natural number; the grounding terminal is connected to one respective end of N?i keys of the N keys, and the other end of the N?i keys is connected to N?i collection ports of the M collection ports respectively. With the disclosure, the number of signal collection ports can be reduced and the cost of a mouse can be lowered.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: April 21, 2015
    Assignee: Beijing Sigmachip Co. Lt
    Inventors: Zhiqian Li, Lun Lv, Yongqing Yan
  • Patent number: 8719687
    Abstract: A computer-implementable method for creating a summary video with depth information, comprising: recognizing moving objects from the input original video; generating an animated moving object cutout for each of the recognized moving objects by duplicating and stacking successive frames in the input original video containing images of the respective moving object; constructing a scene background by using texture of scenes in the input original video and estimating any missing portion; rendering a Dynamic 3D Scene by using depth information of foreground objects in the input original video and the scene background to create a three-dimensional scene and overlaying the animated moving object cutouts on to the three-dimensional scene according to their respective longitude, latitude, and depth locations in the three-dimensional scene; and synthesizing the summary video, by using the Dynamic 3D Scene.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: May 6, 2014
    Assignee: Hong Kong Applied Science and Technology Research
    Inventors: Tai Pang Wu, Zhiqian Li, Xiao Zhou, Chun Man Lawrence Mak
  • Publication number: 20130163961
    Abstract: A computer-implementable method for creating a summary video with depth information, comprising: recognizing moving objects from the input original video; generating an animated moving object cutout for each of the recognized moving objects by duplicating and stacking successive frames in the input original video containing images of the respective moving object; constructing a scene background by using texture of scenes in the input original video and estimating any missing portion; rendering a Dynamic 3D Scene by using depth information of foreground objects in the input original video and the scene background to create a three-dimensional scene and overlaying the animated moving object cutouts on to the three-dimensional scene according to their respective longitude, latitude, and depth locations in the three-dimensional scene; and synthesizing the summary video, by using the Dynamic 3D Scene.
    Type: Application
    Filed: December 23, 2011
    Publication date: June 27, 2013
    Applicant: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Tai Pang Wu, Zhiqian Li, Xiao Zhou, Chun Man Lawrence Mak
  • Publication number: 20130057474
    Abstract: The disclosure discloses a mouse key identification circuit, a mouse key identification device and a mouse. The mouse key identification circuit comprises: N keys, M collection ports, a Light-Emitting Diode (LED) driver circuit and a grounding terminal, wherein part or all of i keys in N keys are connected to the LED port of the LED driver circuit by one respective end, while the other end of the i keys is connected to i collection ports of the M collection ports respectively, wherein i is less than N and N is a natural number; the grounding terminal is connected to one respective end of N?i keys of the N keys, and the other end of the N?i keys is connected to N?i collection ports of the M collection ports respectively. With the disclosure, the number of signal collection ports can be reduced and the cost of a mouse can be lowered.
    Type: Application
    Filed: September 3, 2012
    Publication date: March 7, 2013
    Applicant: BEIJING SIGMACHIP CO. LTD
    Inventors: Zhiqian LI, Lun LV, Yongqing YAN
  • Patent number: 8077925
    Abstract: The present invention discloses a method for motion sensing of sub-pixel level precision. The method comprises the following steps: acquiring a reference image (reference frame) and a sample image (sample frame) of a surface; calculating the correlation between the reference frame and the sample frame to obtain a motion vector of a photoelectric mouse with respect to this surface; subjecting the reference frame and the sample frame to interpolation to obtain the interpolated reference frame and the interpolated sample frame; calculating the correlation between the interpolated reference frame and the interpolated sample frame in order to correct the aforesaid motion vector and to obtain the movement of the sub-pixel. The precision of displacement measurement can be improved effectively by this method under the condition that sensor's characteristics are not changed to improve the performance of the photoelectric mouse.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: December 13, 2011
    Assignee: Beijing Sigmachip Co., Ltd
    Inventors: Yongqing Yan, Zhiqian Li
  • Publication number: 20090324019
    Abstract: The present invention discloses a method for motion sensing of sub-pixel level precision. The method comprises the following steps: acquiring a reference image (reference frame) and a sample image (sample frame) of a surface; calculating the correlation between the reference frame and the sample frame to obtain a motion vector of a photoelectric mouse with respect to this surface; subjecting the reference frame and the sample frame to interpolation to obtain the interpolated reference frame and the interpolated sample frame; calculating the correlation between the interpolated reference frame and the interpolated sample frame in order to correct the aforesaid motion vector and to obtain the movement of the sub-pixel. The precision of displacement measurement can be improved effectively by this method under the condition that sensor's characteristics are not changed to improve the performance of the photoelectric mouse.
    Type: Application
    Filed: November 17, 2008
    Publication date: December 31, 2009
    Applicant: BEIJING SIGMACHIP CO., LTD.
    Inventors: Yongqing YAN, Zhiqian LI
  • Patent number: 7598752
    Abstract: The disclosure relates to a touch sensing device and method. An embodiment of the disclosed method includes starting to count with a counter while charging a sensing point which has distributed capacitance periodically, then transferring the charge on the sensing point to a second capacitor. Next, the voltage on the second capacitor is compared with a reference voltage, and if the former exceeds the latter, the counter stops counting and saving the value. If the voltage on the second capacitor is less than the reference voltage, the sensing point is judged to determine whether it is in touching state or in non-touching state according to the saved count value while discharging the second capacitor, clearing the counter after the discharge, then restarting the method. Using the device and method of this disclosure, the touching sensing action can be tested accurately.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: October 6, 2009
    Assignee: Beijing, Sigmachip Co., Ltd.
    Inventor: Zhiqian Li
  • Publication number: 20070247172
    Abstract: The disclosure relates to a touch sensing device and method. An embodiment of the disclosed method that comprises starting to count with a counter while charging a sensing point which has distributed capacitance periodically, then transferring the charge on the sensing point to a second capacitor. Next, the voltage on the second capacitor is compared with a reference voltage, and if the former exceeds the latter, the counter stops counting and saving the count value. If the voltage on the second capacitor is less than the reference voltage, the sensing point is judged to determine whether it is in a touching state or in a non-touching state according to the saved count value while discharging the second capacitor, clearing the counter after the discharge, then restarting the method. Using the device and method of this disclosure, the touching sensing action can be tested accurately.
    Type: Application
    Filed: December 29, 2006
    Publication date: October 25, 2007
    Inventor: Zhiqian Li