Abstract: The invention provides a diagnostic kit for metastasis and invasion of breast cancer and a use of an shRNA molecule for silencing expression of human LINC01614. The shRNAs obtained by the invention can interfere with the expression of LINC01614, thereby reducing the migration and invasion ability of tumor cells, inhibiting the expression of EMT proteins, and inhibiting tumor formation and lung metastasis in an animal model in vivo. The invention provides a new solution for targeted therapy of breast cancer. Therefore, the kit for diagnosing metastasis and invasion of breast cancer and the medication for treating metastasis and invasion of breast cancer are developed. The invention provides a new way and strategy for diagnosing and treating metastasis and invasion of breast cancer.

Abstract: The present invention relates to a method of preparing xylitol by using a xylose secondary mother liquor through fermentation. In the method, fermentation treatment is performed on a mixed liquid of the xylose secondary mother liquor and a xylose concentrate, and the xylose secondary mother liquor is subsequently batch-fed instead of glucose in the fermentation process. Thus, a glucose content in the fermentation system is stabilized, and some xylose is provided at the same time. In this way, the use amount of glucose and costs are reduced, and the system xylose can be relatively stabilized, thus improving the entire conversion rate. In the present invention, adding the xylose secondary mother liquor by mixed fermentation and batch feeding and the like enables the contents of heterosaccharides such as arabinose and mannose in the fermentation system to be always within a range of metabolization by fermenting strains, facilitating subsequent purification and improving the xylitol purity.

Abstract: The present invention provides a method of improving a biomass high-solid enzymatic hydrolysis rate. By screening particle sizes of the biomass substrate, different water content controls are performed on coarse and fine particle biomass substrates and then an entire water content of the mixture of the coarse and fine particle biomass substrates is controlled to achieve a reduced initial viscosity of the enzymatic hydrolysis and improve liquefaction speed, and finally improve the biomass high-solid enzymatic hydrolysis rate. The enzymatic hydrolysis system of the present invention can be easily constructed with lower equipment requirements, lower energy consumption, higher enzymatic hydrolysis efficiency and simpler operation process, helping the industrial production and applications.

Abstract: An atomizer includes a liquid storage shell, an ultrasonic atomizing core, a liquid transporting cotton, a cooling block, and an end cap. The liquid storage shell surrounds the liquid storage cavity and the functional cavity which are isolated from each other, wherein the liquid storage cavity is used for storing liquid. The ultrasonic atomizing core is assembled in the functional cavity. The liquid transporting cotton is connected to the ultrasonic atomizing core and inserted into the liquid storage cavity, so as to transport the liquid in the liquid storage cavity to the ultrasonic atomizing core. The cooling block is attached on one side of the ultrasonic atomizing core. The cooling block has an atomizing hole and an oil return hole. The end cap is connected to one end of the liquid storage shell to seal the liquid storage cavity and the functional cavity.

Abstract: The present disclosure provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present disclosure further discloses methods of making and using the FIX fusion proteins.

Abstract: The present invention provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present invention further discloses methods of making and using the FIX fusion proteins.

Abstract: The present invention provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present invention further discloses methods of making and using the FIX fusion proteins.

Abstract: An atomizer includes a liquid storage shell, an ultrasonic atomizing core, a liquid transporting cotton, a cooling block, and an end cap. The liquid storage shell surrounds the liquid storage cavity and the functional cavity which are isolated from each other, wherein the liquid storage cavity is used for storing liquid. The ultrasonic atomizing core is assembled in the functional cavity. The liquid transporting cotton is connected to the ultrasonic atomizing core and inserted into the liquid storage cavity, so as to transport the liquid in the liquid storage cavity to the ultrasonic atomizing core. The cooling block is attached on one side of the ultrasonic atomizing core. The cooling block has an atomizing hole and an oil return hole. The end cap is connected to one end of the liquid storage shell to seal the liquid storage cavity and the functional cavity.

Abstract: The present invention provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present invention further discloses methods of making and using the FIX fusion proteins.