Patents by Inventor Zhiqiang Liu

Zhiqiang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250115613
    Abstract: The present invention provides a diaryl compound as a tubulin/Src dual target inhibitor. The present invention also provides a diaryl compound represented by formula I, a tautomer, a stereoisomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof. The diaryl compound can be used as a dual target inhibitor against tubulin and Src kinase and can also be used as a mono-target inhibitor against tubulin or Src kinase. The compound of the present invention can significantly inhibit the polymerization of tubulin monomers and cell proliferation.
    Type: Application
    Filed: January 13, 2023
    Publication date: April 10, 2025
    Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
    Inventors: Xuejun ZHANG, Yang ZANG, Hui YANG, Sijun LEI, Wenjun WEI, Zhiqiang WU, Lifei LIU, Xin ZHANG, Li'e LI, Jun YANG
  • Patent number: 12272305
    Abstract: A display substrate and a display device are disclosed. The display substrate includes a light-transmitting region, wherein the light-transmitting region includes a plurality of rows of effective sub-pixel sets and a plurality of main spacers, each row of the plurality of rows of effective sub-pixel sets includes a plurality of effective sub-pixel sets, each of the plurality of effective sub-pixel sets includes a plurality of effective sub-pixels, any two adjacent effective sub-pixel sets in a same row are spaced apart from each other by one main spacer, the main spacer includes at least two sub-spacers arranged along a column direction. At least two sub-spacers arranged along a row direction have different widths; and/or at least two sub-spacers of a same main sub-spacer have different widths.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: April 8, 2025
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Zhiqiang Xu, Wei Qin, Chunfang Zhang, Weixing Liu, Tieshi Wang, Xuefei Sun
  • Publication number: 20250113104
    Abstract: A substation inspection device includes a rack, an anti-vibration mechanism, a camera apparatus and a lock-stop apparatus. The anti-vibration mechanism is mounted on the rack. The camera apparatus includes a first mounting seat and a camera assembly. The first mounting seat is mounted on the rack through the anti-vibration mechanism. The camera assembly is mounted on the first mounting seat. The lock-stop apparatus is mounted on the rack and is configured to fix the camera apparatus.
    Type: Application
    Filed: July 31, 2024
    Publication date: April 3, 2025
    Inventors: Xuefeng NING, Yi RAO, Dexing SUN, Wanwei WANG, Guanke LIU, Xiliang DAI, Rongfu ZHONG, Wei WEI, Zhiqiang LIN, Zehuai LIU, Zhantu YUAN, Long LI, Yuanjia LI, Chuanming TAN, Yongyuan WANG, Dawei LU, Libin QIN, Wenrui CHEN, Haipeng ZHANG
  • Patent number: 12265239
    Abstract: Provided is a wide angle application high reflective mirror having a reflection band partially overlapping in a wavelength range of 800-4000 nm. The mirror comprises a film system in which a plurality of high refractive index film layers and a plurality of low refractive index film layers that are alternately stacked, and the material of the high refractive index film layer is one of SiH, SiOxHy, or SiOxNy, or a mixture thereof. The highly reflective mirror can achieve a reflectance greater than 99% with an incident angle ranging from 0 to 60 degrees over a large angle range.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: April 1, 2025
    Assignee: II-VI DELAWARE, INC.
    Inventors: Li Wu, Zhe Liu, Guanglong Yu, Yu Li, Yan Su, Zhiqiang Lin
  • Patent number: 12267590
    Abstract: A substation inspection device includes a rack, an anti-vibration mechanism, a camera apparatus and a lock-stop apparatus. The anti-vibration mechanism is mounted on the rack. The camera apparatus includes a first mounting seat and a camera assembly. The first mounting seat is mounted on the rack through the anti-vibration mechanism. The camera assembly is mounted on the first mounting seat. The lock-stop apparatus is mounted on the rack and is configured to fix the camera apparatus.
    Type: Grant
    Filed: July 31, 2024
    Date of Patent: April 1, 2025
    Assignee: DONGGUAN POWER BUREAU OF GUANGDONG POWER GRID CO., LTD.
    Inventors: Xuefeng Ning, Yi Rao, Dexing Sun, Wanwei Wang, Guanke Liu, Xiliang Dai, Rongfu Zhong, Zhiqiang Lin, Wei Wei, Zehuai Liu, Zhantu Yuan, Long Li, Yuanjia Li, Chuanming Tan, Yongyuan Wang, Dawei Lu, Libin Qin, Wenrui Chen, Haipeng Zhang
  • Patent number: 12252487
    Abstract: Disclosed are sodium salts of pyrimidine derivatives, and a series of crystal forms thereof. The series of crystal forms exhibit a good druggability, such as stability, fluidity, compressibility, etc., and provide a variety of options of APIs for subsequent drug product development.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: March 18, 2025
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Xiaoxin Chen, Chengwu Liu, Zhuowei Liu, Zhenyou Tan, Zhiqiang Liu, Zhiwei Cheng, Chaofeng Long, Jiajun Huang, Guangqiang Zhou
  • Patent number: 12253753
    Abstract: A display panel includes a liquid crystal cell, a first polarizing assembly and a second polarizing assembly. The liquid crystal cell includes a first substrate and a second substrate disposed opposite to each other, and a liquid crystal layer disposed between the first substrate and the second substrate. The first polarizing assembly is disposed on a side of the first substrate further away from the liquid crystal layer and includes at least a first polarizing layer having a first transmission axis, and the first polarizing assembly is configured for generating polarized light whose polarization direction is parallel to the first transmission axis. The second polarizing assembly is located on a side of the second substrate further away from the liquid crystal layer and includes at least a transflective layer and a light absorbing layer.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: March 18, 2025
    Assignees: Beijing BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Jiaxing Wang, Feng Liu, Xiaojuan Wu, Jian Wang, Yao Bi, Jinshuai Duan, Cuiyu Chen, Yu Zhao, Dawei Feng, Zhiqiang Yu, Danxing Hou, Ning Wang, Mingjing Liu, Yichi Zhang
  • Publication number: 20250084082
    Abstract: The present invention provides a huperzine B crystal and a preparation thereof. Specifically, the present invention provides a crystal form A of the huperzine B crystal. An X-ray diffraction pattern of the crystal form A has the following 2? angular characteristic absorption peak: 9.56±0.2, 13.90±0.2, 14.88±0.2, 16.00±0.2, 25.39±0.2, and 28.78±0.2.
    Type: Application
    Filed: July 13, 2022
    Publication date: March 13, 2025
    Inventors: Delong XIE, Wangzhou CHI, Yonggang LI, Xuhua HU, Bo GU, Dongyan SUN, Zhiqiang LIU, Baosheng YIN
  • Publication number: 20250088215
    Abstract: Disclosed are a display base plate, a driving method and a display apparatus. The display base plate includes a display area and a border area, the display area including a first display area and a second display area, and the display base plate including: a substrate, and a display signal line, a communication signal line and a compensation signal line, wherein the display signal line is configured to transmit a display signal to a pixel unit of the display area; the communication signal line is coupled with the display signal line to form a coupling capacitance, and includes a first communication signal line, at least part of the first communication signal line is located in the first display area, and the first communication signal line is configured to transmit a communication signal; and the compensation signal line is located in the border area, is connected to the first communication signal line.
    Type: Application
    Filed: January 13, 2023
    Publication date: March 13, 2025
    Applicants: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE Technology Group Co., Ltd.
    Inventors: Dawei Feng, Xiaojuan Wu, Yu Zhao, Zhiqiang Yu, Feng Liu, Jiaxing Wang, Jinshuai Duan, Cuiyu Chen, Ning Wang, Danxing Hou, Jian Wang, Biqi Li
  • Publication number: 20250085805
    Abstract: A touch interaction device includes an electronic device including a screen, an accessory device subordinate to the electronic device, and at least one sensing device. The at least one sensing device is disposed at a bottom of the accessory device, or the at least one sensing device is disposed at the bottom of the accessory device and on the electronic device. The electronic device is configured to: determine whether the accessory device is placed on the screen of the electronic device according to sensing information of the at least one sensing device; determine a screen shielding area according to position information of the at least one sensing device in a case where the accessory device is placed on the screen of the electronic device; and adjust touch scanning frequency of the screen shielding area and turn off display drive of the screen shielding area according to the screen shielding area.
    Type: Application
    Filed: February 21, 2023
    Publication date: March 13, 2025
    Applicants: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Zhiqiang WANG, Ping LUO, Guiyu ZHANG, Shuai LIU, Liqing JIANG, Shukui YANG
  • Publication number: 20250084577
    Abstract: A laundry apparatus including an outer tub, a window pad, a drainage pump, a valve assembly, and a fan, the drainage pump is in communication with the outer tub by a pump pipe; the valve assembly includes a blocking mechanism and a valve shell having an air intake cavity and an air output cavity; the air intake cavity and the air output cavity are independently arranged; the air intake cavity is in communication with an air intake pipeline which provides communication between the outside and the pump pipe or the bottom of the outer tub; the air output cavity is in communication with an air output pipeline which provides communication between the outside and the window pad; the fan is arranged on the air intake pipeline and/or the air output pipeline; and the blocking mechanism is configured to simultaneously block the air intake pipeline and the air output pipeline.
    Type: Application
    Filed: June 17, 2022
    Publication date: March 13, 2025
    Applicants: Qingdao Haier Laundry Electric Appliances Co., Ltd, Haier Smart Home Co., Ltd.
    Inventors: Kai LIU, Sheng XU, Zhiqiang ZHAO
  • Patent number: 12249280
    Abstract: The present application discloses a display panel and a display device. The display panel comprises pixel circuits, collecting modules and feedback modules, and the pixel circuit comprises a driving module, a data writing module and a light-emitting module; wherein the data writing module is configured to transmit a voltage output by a data signal terminal to the driving module; the driving module and the light-emitting module are electrically connected between a first power supply terminal and a second power supply terminal, and the driving module is configured to generate a driving current according to the voltage from the data signal terminal and a voltage from the first power supply terminal to drive the light-emitting module to emit light; the collecting module is configured to collect at least one of a voltage actually received by the driving module and a voltage actually received by the driving module.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: March 11, 2025
    Assignee: XIAMEN TIANMA DISPLAY TECHNOLOGY CO., LTD.
    Inventors: Qingyue Zhang, Xiaoyong Liu, Zhida Zhu, Jingxiong Zhou, Zhiqiang Xia
  • Publication number: 20250079568
    Abstract: Disclosed is a fully immersed energy storage device, which includes a casing and a water pump. An insulation box is mounted inside the casing, and the insulation box is assembled with an assembly plate thereon. A mounting platform is mounted on the assembly plate and assembled with an annular rack. A rotating groove is provided between the mounting platform and the annular rack. Balls are placed in the rotating groove. The mounting platform is assembled with an assembly block, on which a rotating shaft is mounted. One end of the rotating shaft connects to a gear. The other end of the rotating shaft connects to a first assembly rod, to which a second assembly rod is connected. The second assembly rod connects to a fixed block, which is connected to an energy storage box. A motor base is mounted on the casing. A motor is mounted on the motor base.
    Type: Application
    Filed: August 15, 2023
    Publication date: March 6, 2025
    Applicant: CSG PWR GEN (GUANGDONG) ENERGY STOR TECH CO., LTD
    Inventors: Zhiqiang WANG, Chao DONG, Bangjin LIU, Sheng WAN, Jin WANG, Di XIAO, Jiasheng WU, Man CHEN, Yumin PENG, Yueli ZHOU, Cheng PENG, Min ZHANG, Bin WU, Linwei WANG, Qihua LIN, Xiaodong ZHENG, Zheng WENG, Shaohua ZHAO, Lunsen ZOU
  • Publication number: 20250076700
    Abstract: Embodiments of the present disclosure provide a display module and a preparation method therefor, and a display apparatus. The display module includes a liquid crystal display panel and a light scattering layer. Among them, the liquid crystal display panel includes a first substrate, a second substrate, and a first liquid crystal layer, the first substrate is disposed opposite to the second substrate, the first liquid crystal layer is located between the first substrate and the second substrate, and the first liquid crystal layer includes a cholesteric liquid crystal configured to have a conical helix texture when an electric field is applied, to reflect light matched with a helical pitch of the conical helix texture; and the light scattering layer is disposed on a side of the liquid crystal display panel and is configured to scatter light reflected by the liquid crystal display panel.
    Type: Application
    Filed: November 16, 2022
    Publication date: March 6, 2025
    Inventors: Xiaojuan WU, Jinshuai DUAN, Jiaxing WANG, Cuiyu CHEN, Feng LIU, Dawei FENG, Zhiqiang YU, Ning WANG, Danxing HOU, Mingjing LIU, Yichi ZHANG
  • Patent number: 12242687
    Abstract: A touch display device, including: a touch display substrate, provided with a display region and a non-display region provided adjacent to the display region, wherein the non-display region is provided with a display bonding region and a touch bonding region; and a flexible circuit board, provided with a touch signal line, a touch chip and a display signal line, wherein the touch signal line is connected with the touch chip, the flexible circuit board is bound with the touch display substrate in the display bonding region and the touch bonding region, the touch chip is connected to the touch bonding region through the touch signal line, and the display signal line is connected to the display bonding region; where the touch chip, the touch signal line and the touch bonding region are provided on a same side of the display signal line.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: March 4, 2025
    Assignees: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD
    Inventors: Zewen Li, Wenxiao Niu, Hengzhen Liang, Xu Lu, Lianbin Liu, Zhiqiang Wang, Rendong Li, Yu Wang
  • Publication number: 20250065815
    Abstract: The present application discloses a base station for mounting vehicle accessories. The base station includes a first guide rail, a second guide rail and a mounting portion. The first guide rail and the second guide rail are mounted on the back side of the vehicle-mounted display screen, and the second guide rail is connected to the first guide rail; the first guide rail and the second guide rail are used to mount multiple vehicle accessories at the same time, the mounting portion is connected to at least one of the first guide rail and the second guide rail, the first guide rail and the second guide rail are fixed to the vehicle-mounted display screen via the mounting portion. The base station for mounting vehicle accessories of the present application can reduce damage to the vehicle-mounted display screen caused by the mounting of vehicle accessory.
    Type: Application
    Filed: November 23, 2023
    Publication date: February 27, 2025
    Inventors: SHUAI ZHANG, ZHIQIANG ZHAO, CHANGJIANG LIU, LIWEI CHEN, GUOQING SUN
  • Publication number: 20250069554
    Abstract: A shift register, a driving circuit, a driving method and a display device are provided. The shift register includes: an input circuit configured to provide a first voltage or a second voltage to a first node and a light-emitting control signal terminal under a control of a first input signal and a second input signal; a processing circuit configured to provide the first voltage or the second voltage to a second node under a control of the first input signal and a potential of the first node; and an output circuit configured to provide the first voltage or the second voltage to a first output scanning signal terminal under control of a first clock signal and the potential of the first node, and provide the first voltage or the second voltage to a second output scanning signal terminal under a control of a potential of the first output scanning signal terminal.
    Type: Application
    Filed: August 22, 2023
    Publication date: February 27, 2025
    Inventors: Weixing Liu, Wanpeng Teng, Zhiqiang Xu, Chunfang Zhang, Meirong Lu, Jintao Peng, Xinxing Wang, Huanhuan Wang
  • Patent number: 12236911
    Abstract: A display method is provided. The display method includes providing a display panel having a plurality of subpixels, a respective subpixel of the plurality of subpixels including a first area, n1 number of second areas, and n2 number of third areas, the first area being between the n1 number of second areas and the n2 number of third areas, n1?1, and n2?1; for displaying a first frame of image, controlling light emission of the respective subpixel to be limited in the first area, m1 number of the n1 number of second areas, and m2 number of the n2 number of third areas; and for displaying a second frame of image, controlling light emission of the respective subpixel to be limited in the first area, m1? number of the n1 number of second areas, and m2? number of the n2 number of third areas.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: February 25, 2025
    Assignee: BOE Technology Group Co., Ltd.
    Inventors: Xiaolong Li, Kuanjun Peng, Kai Guo, Wanpeng Teng, Chunfang Zhang, Weixing Liu, Zhiqiang Xu, Tieshi Wang, Feihu Zhou
  • Patent number: 12236824
    Abstract: The present disclosure provides a gate driving circuit, a method of driving a gate driving circuit, and a display panel. The gate driving circuit includes a plurality of driving units connected in cascade. Each driving unit includes: N shift register units; and a mode control circuit connected to the N shift register units, wherein the mode control circuit is configured to receive a control signal for the driving unit, and connect the N shift register units in one of a plurality of resolution modes under the control of the control signal.
    Type: Grant
    Filed: October 20, 2023
    Date of Patent: February 25, 2025
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Weixing Liu, Wei Qin, Kuanjun Peng, Tieshi Wang, Chunfang Zhang, Hui Zhang, Changfeng Li, Shunhang Zhang, Kai Hou, Hongrun Wang, Liwei Liu, Yunsik Im, Wanpeng Teng, Xiaolong Li, Kai Guo, Zhiqiang Xu
  • Patent number: 12233085
    Abstract: An application of hyaluronic acid in preparing medicines for preventing or treating ferroptosis-related diseases is provided, and an application of hyaluronic acid or salts of hyaluronic acid or derivatives of hyaluronic acid in preparing medicines for inhibiting ferroptosis is also provided. According to the present application, the anti-ferroptosis function of hyaluronic acid is disclosed. The hyaluronic acid is the first natural extracellular matrix material with anti-ferroptosis function found at present. The hyaluronic acid is one of the components of natural extracellular matrix and exists in large quantities in human body and is also a widely used material in clinic.
    Type: Grant
    Filed: September 4, 2023
    Date of Patent: February 25, 2025
    Assignees: ACADEMY OF MILITARY MEDICAL SCIENCES, ACADEMY OF MILITARY SCIENCES OF CHINESE PLA, BEIJING JIUYU ONCOLGY CO LTD
    Inventors: Zhiqiang Liu, Zengqiang Yuan, Xiaowen Xing, Bingshui Xiu, Shihong Liu