Abstract: Provided is a method for preparing bencaosome comprising the steps of: mixing one or more lipid components with any one or more of the following: nucleic acid, compound and macromolecules, and treating the obtained mixture by heating. Also provided is a method for extracting decoctosome from plants comprising the steps of: preparing an extract of the plant with a solvent; performing differential centrifugation to the extract; resuspending the precipitates with an aqueous solution to provide the decoctosome.

Abstract: A multi-objective optimized evaluation method of anti-seismic performance of a slope reinforced by a pile-anchor system is provided. The method includes: training an initial three-dimensional slope numerical calculation model to obtain an target three-dimensional slope numerical calculation model; determining numerical values to be imported into the target three-dimensional slope numerical calculation model according to deformation differences, to obtain a model analysis result; obtaining a simulation operation result according to a reinforcement scheme working condition table of the pile-anchor system; based on the model analysis result and the simulation operation result, evaluating anti-seismic reinforcing performance of the pile-anchor system to obtain comprehensive evaluation values, and then optimizing and evaluating the reinforcement schemes of an overall slope to be reinforced.

Abstract: The present disclosure provides an earphone including a core module. The core module may include a core housing and a core. The core housing may include a bottom wall and an annular peripheral wall. When a user wears the earphone, the bottom wall may face the head of the user. One end of the annular peripheral wall may be integrally connected with the bottom wall, the other end of the annular peripheral wall that is away from the bottom wall includes an opening, and the core may be disposed in the core housing through the opening. The core may include a magnet configured such that the core module is attachable to a magnetic object through one side of the bottom wall.

Abstract: The present disclosure discloses an acoustic device and a support assembly thereof. The support assembly may include a shell configured to provide a space for accommodating one or more components of the acoustic device. The support assembly may further include an interaction assembly configured to realize an interaction between a user and the acoustic device, wherein the interaction assembly include a first component and one or more second components, in response to receiving an operation of the user, the first component is configured to trigger at least one of the one or more second components to cause the acoustic device to perform a function corresponding to the at least one of the one or more second components.

Abstract: The present disclosure mainly relates to an earphone, comprising a core module and a hook structure. The core module is disposed on a front side of an ear in a wearing state. At least a portion of the hook structure is disposed at a rear side of the ear in the wearing state. The core module includes a core housing and a loudspeaker. The hook structure includes an adapter housing connected with the core housing. At least a portion of the adapter housing is disposed at the front side of the ear in the wearing state. The adapter housing forms an accommodation cavity and one or more through holes communicated with the accommodation cavity. The earphone includes one or more electrode terminals at least partially disposed in the one or more through holes.

Abstract: Provided is a method for preparing bencaosome comprising the steps of: mixing one or more lipid components with any one or more of the following: nucleic acid, compound and mancromolecules, and treating the obtained mixture by heating. Also provided is a method for extracting decoctosome from plants comprising the steps of: preparing an extract of the plant with a solvent; performing differential centrifugation to the extract; resuspending the precipitates with an aqueous solution to provide the decoctosome.

Abstract: The present disclosure concerns recombinant yeast host cells having a first genetic modification to express a heterologous polypeptide or to over-express a native polypeptide. The recombinant yeast host cells also have a second genetic modification to at least partially mitigate the reduction in growth rate resulting from the expression of the heterologous polypeptide or the over-expression of the native polypeptide. The second genetic modification can be, for example, to favor the secretion of the heterologous or native polypeptide.

Abstract: The present application discloses a VICTS antenna based on an RGW structure, comprising an RGW feeding layer and a radiation layer arranged in sequence, wherein the RGW feeding layer comprises an RGW power splitter and a dielectric substrate for slow wave design, and the RGW power splitter is arranged under the dielectric substrate, wherein a power splitting network cover plate is arranged between the RGW feeding layer and the radiation layer, wherein the RGW power splitter comprises a feeding network and a waveguide feeding port, through which signals are input into the feeding network; the radiation layer is composed of a plurality of CTS arrays. During signal transmission, the signals are input into the feeding network through the waveguide port, and then the signals are fed into each CTS array by the feeding network; the radiation layer is configured to rotate.

Abstract: Described is a nucleic acid ligand, a mixture thereof, and the use thereof. The mixture contains two or more nucleic acid polymerase substrate analogs. The nucleic acid polymerase substrate analog is a single nucleic acid molecule or nucleic acid molecule analog which forms complementary pairing within a molecule, or a single or two nucleic acid molecules or nucleic acid molecule analogs which form complementary pairing between molecules; and a structure formed thereby has the characteristics of a nucleic acid polymerase substrate. The nucleic acid polymerase substrate analog is suitable for all polymerases and can be widely used in the field of nucleic acid amplification. The 3? end of the nucleic acid ligand has a modification which inhibits the extension thereof.

Abstract: Provided is a method for preparing bencaosome comprising the steps of: mixing one or more lipid components with any one or more of the following: nucleic acid, compound and mancromolecules, and treating the obtained mixture by heating. Also provided is a method for extracting decoctosome from plants comprising the steps of: preparing an extract of the plant with a solvent; performing differential centrifugation to the extract; resuspending the precipitates with an aqueous solution to provide the decoctosome.

Abstract: The present application relates to extracting a plurality of compounds from a traditional Chinese medicine, or synthesizing a compound capable of promoting nucleic acid delivery, and utilizing the extracted compound, or a plurality of combinations to promote absorption and entry of a nucleic acid such as sRNA into a target cell, and to facilitate the entry of a nucleic acid into a target site in a subject in need thereof

Abstract: The results herein identify Sp17 as a novel cancer-testis antigen in multiple myeloma. Sp17 recombinant protein was generated from E. coli. A CD8 predominant CTL line was generated that was able to lyse autologous targets in a Sp17-dependent HLA class I-restricted manner, using dendritic cells as the antigen-presenting cells and DOTAP to deliver the Sp17 protein to the dendritic cells. A combination of HLA-matched and mismatched antibody-enriched fresh myeloma tumor cells and myeloma cell lines were used as targets for the recombinant protein-propagated CTL. The findings of target cell lysis suggest that the Sp17 protein produced by Sp17+ tumor cells are processed and presented in vivo and that the CTL epitopes are presented in association with HLA class I molecules in a concentration and configuration recognized by recombinant protein-propagated CTL.

Abstract: The present invention relates to methods for diagnosing cancer in a subject The method involves obtaining a biological sample from a subject and measuring SPAN-Xb expression level in the biological sample. The SPAN-Xb expression level in the biological sample is compared to the SPAN-Xb expression level in a control sample from a subject devoid of cancer, where a greater SPAN-Xb expression level in the biological sample compared to the SPAN-Xb expression level in the control sample is indicative of the subject having cancer. Methods for monitoring progression/regression of cancer in a subject are also disclosed. The present invention also relates to methods of treating a subject with cancer. The method involves administering to the subject a therapeutically effective amount of an agent capable of eliciting an immunological response against SPAN-Xb protein or specifically recognizing a SPAN-Xb protein, under conditions effective to-treat a cancer characterized by cells expressing SPAN-Xb.

Abstract: The results herein identify Sp17 as a novel cancer-testis antigen in multiple myeloma. Sp17 recombinant protein was generated from E. coli. A CD8 predominant CTL line was generated that was able to lyse autologous targets in a Sp17-dependent HLA class I-restricted manner, using dendritic cells as the antigen-presenting cells and DOTAP to deliver the Sp17 protein to the dendritic cells. A combination of HLA-matched and mismatched antibody-enriched fresh myeloma tumor cells and myeloma cell lines were used as targets for the recombinant protein-propagated CTL. The findings of target cell lysis suggest that the Sp17 protein produced by Sp17+ tumor cells are processed and presented in vivo and that the CTL epitopes are presented in association with HLA class I molecules in a concentration and configuration recognized by recombinant protein-propagated CTL.