Abstract: The present disclosure provides an identification method of two parents of a Nymphaea hybrid based on sequences of internal transcribed spacer (ITS) and matK, and belongs to the technical field of plant molecular identification. In the present disclosure, the identification method includes: based on Sanger sequencing, obtaining an ITS sequence of a nuclear genome fragment inherited from the two parents and a matK sequence of a chloroplast genome fragment inherited from a maternal line in the Nymphaea hybrid; subjecting ITS and matK sequences downloaded from a GenBank to strict screening, and establishing a database of the ITS and matK sequence of the Nymphaea; aligning ITS and matK sequences of the Nymphaea of the parents to be determined with respective database, and constructing a neighbor-joining tree based on a genetic distance; and checking specific loci to obtain information on male and female parents of the Nymphaea to be determined.

Abstract: A method for reinforcing an existing stone masonry wall, wherein, the UHPC (ultra high performance concrete) material for reinforcing an existing stone masonry wall as a reinforcing material, comprising following steps: step (1): carrying out a pretreatment to the existing stone masonry wall to be reinforced; step (2): tensioning and thereby reinforcing the existing stone masonry wall pretreated in the step (1); step (3): injecting a prepared UHPC material into the mortar joint by a manual squeezing; step (4): spraying prepared UHPC material onto the existing stone masonry wall that has been treated in the step (3) by a spraying process; step (5): maintaining; the UHPC material includes: 550-600 kg/m3 of silicate cement, 180-200 kg/m3 of white silica fume, 510-530 kg/m3 of limestone powder, 715-735 kg/m3 of quartz sand, 60-75 kg/m3 of iron ore tailings particles, 50-60 kg/m3 of pumice particles, 15-30 kg/m3 of polycarboxylic acid water reducing agent, 230-255 kg/m3 of water and 25-35 kg/m3 of POM fiber.

Abstract: A UHPC material for reinforcing existing stone masonry wall and its reinforcement method are disclosed, which belongs to the technical field of wall reinforcement. The UHPC material for reinforcing existing stone masonry wall includes: 550-600 kg/m3ofsilicate cement, 180-200 kg/m3ofwhite silica fume, 510-530 kg/m3 of limestone powder, 715-735 kg/m3 of quartz sand, 60-75 kg/m3 of iron ore tailings particles, 50-60 kg/m3 of pumice particles, 15-30 kg/m3 of polycarboxylic acid water reducing agent, 230-255 kg/m3 of water and 25-35 kg/m3 of POM fiber; the disclosure uses the combination of improved new UHPC increased cross-section method and steel banding method to strengthen the existing stone masonry wall, which can increase the thickness of the stone masonry wall and it can improve the stability of the wall; significantly improve the seismic performance and durability, and the construction is convenient, so it can be widely used in the seismic reinforcement of the stone masonry wall.

Abstract: The present disclosure provides a microemulsion-based vaccine delivery system, and further provides a preparation method and an application thereof. Using the microemulsion absorbing a series of metal ion compounds, and adding an antigen in a preparation process, antigen entrapment can be realized and a stable vaccine preparation is obtained. The prepared vaccine can effectively be taken up by an antigen-presenting cell and effectively delivered to lymph nodes to induce an antigen-specific immune response, and the same has a wide application prospect.

Abstract: The disclosure provides a method for passivating a silicon carbide epitaxial layer, relating to the technical field of semiconductors. The method includes the following steps: introducing a carbon source and a silicon source into a reaction chamber, and growing a silicon carbide epitaxial layer on a substrate; and turning off the carbon source, introducing a nitrogen source and a silicon source into the reaction chamber, and growing a silicon nitride thin film on an upper surface of the silicon carbide epitaxial layer. The silicon nitride thin film grown by the method has few defects and high quality, and may be used as a lower dielectric layer of a gate electrode in a field effect transistor. It does not additionally need an oxidation process to form a SiO2 dielectric layer, thereby reducing device fabrication procedures.

Abstract: An organic amine ester derivative drug of 2-(?-hydroxypentyl)benzoic acid and a preparation method thereof and an use thereof are disclosed. The present disclosure particularly relates to a compound having the general formula I or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared from the compound or the pharmaceutically acceptable salt thereof. The compound having the general formula I or the pharmaceutically acceptable salt thereof has in vitro a good solubility and a low hygroscopicity, and has in vivo a bioavailability and a brain aggregation concentration that are significantly greater than those of the original medicine butyphthalide and/or an improving drug efficacy. The use of the compound in the preparation of a drug for preventing and/or treating heart and cerebral ischemic diseases, a drug for preventing and/or treating heart and cerebral artery occlusion diseases, an anti-parkinsonian drug and an anti-senile-dementia drug is also disclosed.

Abstract: Disclosed is a circulating device for cooling and heating superconducting magnet components at controllable rate, including a liquid nitrogen tank and a vacuum container. A container for accommodating the superconducting magnet component is provided at an upper end of an interior of the vacuum container. First and second pipelines join and then connect to a top of the liquid nitrogen tank through a coiled pipe. A third pipeline and a first branch of a fourth pipeline join and then connect to an inlet of an electric heater. A PID closed loop for temperature control is provided at the electric heater. A main pipeline of the outlet pipeline of the electric heater is connected to an inlet of the container. A second branch of the fourth pipeline, an outlet pipeline of the container and a branch pipeline of the outlet pipeline of the electric heater communicate with atmosphere.

Abstract: An organic amine ester derivative drug of 2-(?-hydroxypentyl)benzoic acid and a preparation method thereof and an use thereof are disclosed. The present disclosure particularly relates to a compound having the general formula I or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared from the compound or the pharmaceutically acceptable salt thereof. The compound having the general formula I or the pharmaceutically acceptable salt thereof has in vitro a good solubility and a low hygroscopicity, and has in vivo a bioavailability and a brain aggregation concentration that are significantly greater than those of the original medicine butyphthalide and/or an improving drug efficacy. The use of the compound in the preparation of a drug for preventing and/or treating heart and cerebral ischemic diseases, a drug for preventing and/or treating heart and cerebral artery occlusion diseases, an anti-parkinsonian drug and an anti-senile-dementia drug is also disclosed.

Abstract: A compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared using the compound and the salt. The compound represented by formula (I) or the pharmaceutically acceptable salt exhibits significantly higher buildup and concentration in the lungs compared to other tissues, a longer dwell time in the lungs, and/or elevated pharmaceutical efficacy.

Abstract: An in situ phase change gel sustained-release preparation for a small molecule drug and a preparation method thereof. The in situ phase change gel sustained-release preparation comprises a small molecule drug comprising an active pharmaceutical ingredient, a phospholipid, Span, and an ethanol solution. The in situ phase change gel sustained-release preparation has a high concentration of phospholipids combined with Span, and is thus able to reduce the immediate-release of the small molecule drug and extend the release time, and is suitable for various administration routes, such as subcutaneous injection and external administration.

Abstract: Provided is a nRGD polypeptide formed by connecting alanine-alanine-asparagine (AAN) and a polypeptide containing arginine-glycine-aspartic acid (RGD), wherein the nRGD polypeptide can target tumor vessels, tumor cells and tumor-associated macrophages, and mediate the targeted delivery of tumors.

Abstract: A compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared using the compound and the salt. The compound represented by formula (I) or the pharmaceutically acceptable salt exhibits significantly higher buildup and concentration in the lungs compared to other tissues, a longer dwell time in the lungs, and/or elevated pharmaceutical efficacy.

Abstract: Provided is a nRGD polypeptide formed by connecting alanine-alanine-asparagine (AAN) and a polypeptide containing arginine-glycine-aspartic acid (RGD), wherein the nRGD polypeptide can target tumour vessels, tumour cells and tumour-associated macrophages, and mediate the targeted delivery of tumours.