Patents by Inventor Zhiru Xu

Zhiru Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amorphous asiatic tromethamine salt and preparation method thereof
    Patent number: 8962880
    Abstract: An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: February 24, 2015
    Assignee: Shanghai Institute of Pharmaceutical Industry
    Inventors: Guobin Ren, Ying Liu, Jinyao Chen, Xiaoling Huang, Lin Xiao, Li Cai, Zhen Zhang, Xuejun Wu, Haiyan Sun, Quanhai Liu, Liling Jin, Minyu Liu, Yifang Deng, Zhiru Xu, Renhai Chen, Chungang Li, Xiangduan Tan, Yan Qin
  • AMORPHOUS ASIATIC TROMETHAMINE SALT AND PREPARATION METHOD THEREOF
    Publication number: 20140243553
    Abstract: An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
    Type: Application
    Filed: March 21, 2012
    Publication date: August 28, 2014
    Applicant: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
    Inventors: Guobin Ren, Ying Liu, Jinyao Chen, Xiaoling Huang, Lin Xiao, Li Cai, Zhen Zhang, Xuejun Wu, Haiyan Sun, Quanhai Liu, Liling Jin, Minyu Liu, Yifang Deng, Zhiru Xu, Renhai Chen, Chungang Li, Xiangduan Tan, Yan Qin
  • Therapeutic formulations based on asiatic acid and selected salts thereof
    Patent number: 8742167
    Abstract: A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: June 3, 2014
    Assignee: Shanghai Institute of Pharmaceutical Industry
    Inventors: Ying Liu, Quanhai Liu, Yan Qin, Tong Wu, Zhiru Xu, Min-yu Liu, Fei Li, Yan Li, Michael J. Newman
  • Therapeutic Formulations Based on Asiatic Acid and Selected Salts Thereof
    Publication number: 20100331413
    Abstract: A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
    Type: Application
    Filed: January 8, 2009
    Publication date: December 30, 2010
    Inventors: Ying Liu, Quanhai Liu, Yan Qin, Tong Wu, Zhiru Xu, Min-yu Liu, Fei Li, Yan Li, Michael J. Newman
  • Record player
    Patent number: D1017569
    Type: Grant
    Filed: November 8, 2021
    Date of Patent: March 12, 2024
    Inventor: Zhiru Xu