Abstract: The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetr a-hydropyrazolo[1,5-a]pyrimi dine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Abstract: The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetr a-hydropyrazolo[1,5-a]pyrimi dine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Abstract: The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetr a-hydropyrazolo[1,5-a]pyrimi dine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Abstract: A well cementing method is described for improving cementing quality by controlling the hydration heat of cement slurry. By controlling the degree and/or rate of hydration heat release from cement slurry, the method improves the hydration heat release during formation of cement with curing of cement slurry, improves the binding quality between the cement and the interfaces, and in turn improves the cementing quality at the open hole section and/or the overlap section. The cementing method improves cementing quality of oil and gas wells and reduces the risk of annular pressure.

Abstract: The present invention relates to electrode tabs and batteries. The electrode tab includes a first metal strip and a metal connector connected to the first metal strip. A melting point of the metal connector is lower than a melting point of the first metal strip, or a solidus temperature of the metal connector is lower than a solidus temperature of the first metal strip, or a liquidus temperature of the metal connector is lower than a liquidus temperature of the first metal strip. The electrode tab has the advantages of regular shape, which are not only easy to install and assemble, saving assembly costs, but also not easy to be damaged in the process of assembly, transportation and storage. The electrode tab does not affect an overall size of the battery, is more suitable for use in scenarios such as small miniature batteries and power batteries.

Abstract: An intelligent control method for engine initiation, including: determining whether a current driving mode satisfies a predetermined driving mode; when the current driving mode satisfies the predetermined driving mode, acquiring a current remaining capacity of a battery; determining whether the current remaining capacity is greater than a predetermined capacity threshold value; when the current remaining capacity is greater than the predetermined capacity threshold value, not starting an engine, otherwise, acquiring a catalyst temperature and a vehicle operating state; determining, according to the vehicle operating state, whether the catalyst temperature is less than a predetermined temperature threshold value; when the catalyst temperature is not less than the predetermined temperature threshold value, driving the engine to rotate clockwise to start same in a fuel cut-off manner, otherwise, heating a catalyst by a heating plate until the catalyst temperature is not less than the predetermined temperature th

Abstract: This application provides an interface calling simulation method for developing an application program performed by an electronic device. The electronic device receives an interface calling request for a target interface in an application program. The interface calling request includes interface calling information of the target interface. The electronic device identifies, within a simulated interface set for a simulation interface corresponding to the target interface. The simulated interface set includes simulated interfaces that simulate real interfaces in the application program. The electronic device compares the interface calling information of the target interface with interface configuration information of the simulated interface.

Abstract: An electronic device receives an interface calling request for a target interface in an application program. The interface calling request includes interface calling information of the target interface. The device performs an interface query in a simulated interface set that simulates real interfaces in the application program. In accordance with a determination, based on the interface query, that a target simulation interface corresponding to the target interface exists in the simulated interface set, the device intercepts the interface calling request. The device compares the intercepted interface calling information with interface configuration information of the target simulated interface. In accordance with a determination that the interface calling information matches the interface configuration information, the device obtains simulated response data corresponding to the target simulation interface. The device outputs calling response data of the interface calling request.

Abstract: Provided is a gene target region enrichment method and a kit. The method comprises (1) amplifying fragmented DNA comprising a target region by means of a specific probe so as to obtain a captured-extension product, wherein the specific probe comprises a sequence complementary to the target region of the fragmented DNA, and the 3? terminal nucleotide of the specific probe is modified to prevent a ligation reaction at the 3? terminal of the specific probe; and (2) linking the 3? terminal of the captured-extension product obtained in step (1) to linker DNA to obtain a ligation product.

Abstract: A hydrofoil cavitating flow control structure includes a hydrofoil. A primary protuberant stripe is disposed in a middle position of a suction side of the hydrofoil, a plurality of symmetrically-distributed secondary protuberant stripes are disposed obliquely at both sides of the primary protuberant stripe, and the plurality of secondary protuberant stripes are uniformly and equidistantly distributed along the length direction of the primary protuberant stripe. By changing geometric parameters such as an included angle between the primary protuberant stripe and the second protuberant stripe, a ratio of cross section diameters and a distribution spacing of the second protuberant stripes along a chord length direction of the hydrofoil and the like, the shedding of cloud cavitation on a hydrofoil surface is effectively suppressed, and cavitation erosion and pressure pulsation generated by cavitation collapse is reduced, thus improving the operation efficiency and the service life of hydraulic machinery.

Abstract: Embodiments of this application provide a user hearing protection method, apparatus, and electronic device. In the user hearing protection method, after an electronic device enables a hearing protection mode, when an audio output mode is a headset output, sound pressure output by the headset is obtained based on current-frame sound source data; when the sound pressure is greater than a predetermined sound pressure threshold, an instantaneous sound pressure over-standard warning is performed, and an instantaneous sound pressure over-standard protection operation is performed on the electronic device, and a user's hearing can be protected when the instantaneous sound pressure exceeds a standard.

Abstract: The present invention provides an enrichment method for a gene target region, the method comprising: (1) amplifying, by means of a specific probe, fragmented DNA including a target region, and providing a captured extension product, wherein the specific probe comprises a sequence that is complementary to the target region of the fragmented DNA, and a 3?-end nucleotide and a 5?-end nucleotide of the probe are both modified; and (2) adding a ligase to the captured extension product provided in step (1), and providing a ligation product. The invention further provides an enrichment system for a gene target, the system being applicable to the enrichment method for a gene target region provided in the present invention.

Abstract: Embodiments of this application provide a page processing method and related apparatus. The method includes previewing a target page in an application program; obtaining a page structure of the previewed target page, the page structure of the target page identifying a layout of page elements of the target page in the target page; obtaining a page structure of a skeleton screen corresponding to the target page based on the page structure of the target page, the page structure of the skeleton screen identifying a layout of placeholder elements of the skeleton screen on the skeleton screen, the placeholder elements being obtained by processing the page elements; and generating a view file of the skeleton screen according to the page structure of the skeleton screen, the skeleton screen being displayed before the target page is loaded.

Abstract: An electronic device receives an interface calling request for a target interface in an application program. The interface calling request includes interface calling information of the target interface. The device performs an interface query in a simulated interface set that simulates real interfaces in the application program. In accordance with a determination, based on the interface query, that a target simulation interface corresponding to the target interface exists in the simulated interface set, the device intercepts the interface calling request. The device compares the intercepted interface calling information with interface configuration information of the target simulated interface. In accordance with a determination that the interface calling information matches the interface configuration information, the device obtains simulated response data corresponding to the target simulation interface. The device outputs calling response data of the interface calling request.

Abstract: This application discloses an information recommendation method and apparatus, a device, and a storage medium, and belongs to the field of information recommendation. The method includes starting an application program according to a start operation, a first account being logged in in the application program; obtaining a recommended information flow for the first account, recommended information in the recommended information flow including at least one piece of interactive recommended information, the interactive recommended information being information for which a second account generates an interactive message, the first account and the second account having a social relationship; and displaying an information presentation interface, the information presentation interface comprising the recommended information displayed in an information flow form.

Abstract: Provided is a method for estimating optimal efficiency point parameters in an axial-flow PAT power generation mode, including: I1, calculating an axial velocity of an optimal efficiency point; I2, calculating a flow rate of the optimal efficiency point; I3, calculating a theoretical hydraulic head; I4, calculating a frictional hydraulic head loss and a local hydraulic head loss of each segment; I5, calculating an output power of the optimal efficiency point; I6, calculating a hydraulic head of the optimal efficiency point in a power generation mode; and I7, calculating an optimal efficiency. Further provided is a method for estimating a performance curve in an axial-flow PAT power generation mode based on the above method for estimating an optimal efficiency point parameter, including: II1, calculating a normalized flow-hydraulic head curve; II2, calculating a normalized hydraulic head-output power curve; and II3, calculating a hydraulic head-efficiency curve.

Abstract: This application discloses an information recommendation method and apparatus, a device, and a storage medium, and belongs to the field of information recommendation. The method includes starting an application program according to a start operation, a first account being logged in in the application program; obtaining a recommended information flow for the first account, recommended information in the recommended information flow including at least one piece of interactive recommended information, the interactive recommended information being information for which a second account generates an interactive message, the first account and the second account having a social relationship; and displaying an information presentation interface, the information presentation interface comprising the recommended information displayed in an information flow form.

Abstract: Provided is a method for estimating optimal efficiency point parameters in an axial-flow PAT power generation mode, including: I1, calculating an axial velocity of an optimal efficiency point; I2, calculating a flow rate of the optimal efficiency point; I3, calculating a theoretical hydraulic head; I4, calculating a frictional hydraulic head loss and a local hydraulic head loss of each segment; I5, calculating an output power of the optimal efficiency point; I6, calculating a hydraulic head of the optimal efficiency point in a power generation mode; and I7, calculating an optimal efficiency. Further provided is a method for estimating a performance curve in an axial-flow PAT power generation mode based on the above method for estimating an optimal efficiency point parameter, including: II1, calculating a normalized flow-hydraulic head curve; II2, calculating a normalized hydraulic head-output power curve; and II3, calculating a hydraulic head-efficiency curve.

Abstract: Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivaties that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.

Abstract: Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivaties that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.