Patents by Inventor Zhiwei Shi

Zhiwei Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9818185
    Abstract: Disclosed is an ultrasonic imaging method. The method includes: on a basis of performing fuzzy segmentation of a membership function on an echo signal, sequentially dividing an input image into a plurality of fuzzy segments according to a strength of an echo; dividing the image into a plurality of layers accordingly; and performing a spatial neighborhood operation on a membership degree value in the plurality of layers, so as to obtain a space fuzzy segmentation array; in another aspect, determining a manipulated variable vector of the image according to image content-based self-adaptive calculation or user-based input, flexibly weighting and stretching space fuzzy segmentation arrays at the layers according to the manipulated variable vector finally, and adjusting and compounding the input image by using obtained echo increment and brightness compensation, so as to obtain a final output image. Also disclosed is a corresponding ultrasonic imaging apparatus.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: November 14, 2017
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Zhiwei Shi, Yongqiang Dong
  • Publication number: 20170119666
    Abstract: A stable liposomal formulation for ocular delivery of an alpha 2 adrenergic agonist. The formulation contains a liposome that includes a lipid bilayer including a phosphatidylcholine. An alpha 2 adrenergic agonist is encapsulated in the liposome.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 4, 2017
    Inventors: Ting-Bin Yu, Zhiwei Shi, Shih-Horng Su, Tina Howden
  • Publication number: 20170065520
    Abstract: A stable liposomal formulation for treating cancer. The formulation includes liposomes containing one or more of POPC, DMPC, and DOPC and one or more of the anti-cancer drugs sirolimus, umirolimus, and everolimus encapsulated in the liposomes. Also provided are efficient remote film loading methods for loading the liposomes with the anti-cancer drugs and methods for treating cancer with the liposomal formulations.
    Type: Application
    Filed: September 9, 2015
    Publication date: March 9, 2017
    Inventors: Ting-Bin Yu, Zhiwei Shi, Shih-Horng Su
  • Publication number: 20170042809
    Abstract: A stable liposomal formulation for ocular delivery of a carbonic anhydrase inhibitor. The formulation contains (i) a liposome that includes a lipid bilayer formed of a phosphatidylcholine, and (ii) a carbonic anhydrase inhibitor encapsulated in the liposome. Also provided is a method for treating an ocular disorder with the formulation.
    Type: Application
    Filed: August 11, 2015
    Publication date: February 16, 2017
    Inventors: Ting-Bin Yu, Zhiwei Shi, Shih-Horng Su, Tina Howden
  • Publication number: 20160302759
    Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.
    Type: Application
    Filed: June 30, 2016
    Publication date: October 20, 2016
    Inventors: Zhiwei SHI, Ziyan ZHU, Lei ZHU
  • Publication number: 20160196646
    Abstract: Disclosed is an ultrasonic imaging method. The method includes: on a basis of performing fuzzy segmentation of a membership function on an echo signal, sequentially dividing an input image into a plurality of fuzzy segments according to a strength of an echo; dividing the image into a plurality of layers accordingly; and performing a spatial neighborhood operation on a membership degree value in the plurality of layers, so as to obtain a space fuzzy segmentation array; in another aspect, determining a manipulated variable vector of the image according to image content-based self-adaptive calculation or user-based input, flexibly weighting and stretching space fuzzy segmentation arrays at the layers according to the manipulated variable vector finally, and adjusting and compounding the input image by using obtained echo increment and brightness compensation, so as to obtain a final output image. Also disclosed is a corresponding ultrasonic imaging apparatus.
    Type: Application
    Filed: December 3, 2015
    Publication date: July 7, 2016
    Inventors: Zhiwei Shi, Yongqiang Dong