Abstract: Systems, methods, and apparatuses disclosed herein can compensate for imbalances between multiple transport streams of an uplink (UL)-multiple-input and multiple-output (MIMO) transmission. These systems, methods, and apparatuses can adjust one or more signal metrics of multiple recovered transport streams of the UL-MIMO transmission that are received in the presence of imbalances between the multiple transport streams of the UL-MIMO transmission. As an example, these systems, methods, and apparatuses can inject noise into one or more of the multiple recovered transport streams to adjust the one or more signal metrics of the multiple recovered transmission streams to lessen the imbalances between the multiple transmission streams.

Abstract: Disclosed herein are bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation of mutant EGFR kinase, and methods of preparation and uses thereof.

Abstract: The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Abstract: A display device includes a display panel and a composite tape. The display panel includes a display part, a bendable part and a binding part. The display part includes a first surface and a second surface opposite to the first surface. The second surface includes a first region and a second region, and a vertical projection of the binding part on the second surface is located in the first region. The composite tape includes a first film structure and a second film structure, the first film structure is bonded with the second surface, the second film structure includes at least a first part, a vertical projection of the first part on the second surface is located in the first region, and the first part is bonded with the first film structure and the binding part.

Abstract: The present invention relates to a test system and method for a biomass-based blended fuel. The system comprises a feeding device, a mixing tank, a light-sensing device, and a control device; the feeding device comprises at least two fuel bottles; the fuel bottle is connected to the mixing tank by means of an oil pipe; the correspondingly connected oil pipe of each fuel bottle is provided with a flow valve; the light-sensing device comprises a laser disposed above the mixing tank, a light-reflecting mechanism disposed at the bottom in the mixing tank, and a light-sensing mechanism disposed at one side of the light reflecting mechanism; the output end of the light-sensing mechanism is signaled with the input end of the control device; the input end of the laser and the input end of the flow valve is separately signaled with the output end of the control device.

Abstract: Disclosed herein are novel pharmaceutically active compounds and their preparation methods. The compounds inhibit mutant EGFR and are useful in the treatment of oncological diseases.

Abstract: Disclosed herein is 3-[(1H-pyrazol-4-yl) oxy] pyrazin-2-amine compounds of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of modulating, e.g.

Abstract: A method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazo-lo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent. A pharmaceutical combination comprising a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-( 4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent.

Abstract: The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Abstract: Disclosed are methods, systems, and computer-readable medium to perform operations including: receiving, from an application layer of a user equipment (UE), a first uplink packet at a first time; identifying a latency between the first time and a first instance of a periodic transmission resource during which the first uplink packet is transmitted by the UE; and providing information indicative of the latency to the application layer of the UE.

Abstract: A hinge mechanism includes a hinge base and rotating support mechanisms respectively connected to two opposite sides of the hinge base. The rotating support mechanism includes a rotating shaft, a hinge rotating plate and a hinge moving plate. The hinge rotating plate is rotatably connected to the hinge base through the rotating shaft, has a first end adjacent to the rotating shaft and provided with an accommodating groove. The rotating shaft has a speed reducer with a rotating output portion which can rotate along with the rotating shaft. A rotating speed of the rotating output portion is lower than that of the rotating shaft, and the rotating output portion and the hinge moving plate are rotatably connected to each other. The hinge moving plate includes a second support portion, and the second support portion is at least partially located in the accommodating groove.

Abstract: A driving tool, including a driver assembly and a lifting assembly. The driver assembly includes a drivable driver member and a base arranged on the driver member, where the driver member extends longitudinally in a first axis, and a plurality of engagement holes arranged in the first axis are provided on the driver member. The lifting assembly includes a driving wheel that is driven by a power output portion to rotate and a plurality of fitting portions arranged on a periphery of the driving wheel at intervals, where the plurality of fitting portions can be alternately engaged with the corresponding engagement holes, to drive the driver member to move along the first axis, so as to drive the base to move from a starting position to a driven position.

Abstract: Disclosed herein are novel bifunctional compounds formed by conjugating BTK inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.

Abstract: The seismic imaging resolution analysis method comprises: obtaining common-shot gathers and common-detector gathers; in the common-shot gathers, conducting detector focusing analysis on a focus point at (xj, zn) in each source point gather to obtain a source point focal-beam gather; looping all the focus points at a depth zn, and conducting computation on a weighted source-focusing operator Pik† (zn, zn); in the common-detector gathers, conducting source point focusing analysis on an focus point at (xj, zn) in each source point gather to obtain a detector focal-beam gather; Loop all the focus points at a depth zn, and conducting computation on a weighted detector-focusing operator Pik (zn, zn); and conducting computation on a normalized resolution function of a single focus point so as to obtain a horizontal resolution and a definition.

Abstract: The present application discloses a cable arranging mechanism, a connecting plate for distribution and a distribution frame. The cable arranging mechanism provided by the present application includes a first plate body and a second plate body which are capable of being clamped with each other. The first plate body is provided with an opening for a connector of a cable to pass through. When the second plate body and the first plate body are separated from each other, the cable and the connector thereof are capable of passing through the opening. When the second plate body and the first plate body are clamped with each other, at least one through hole for the cable to pass through is formed. The overall space occupied by the cable arranging mechanism provided by the present application is very small.

Abstract: A device for decomplexation and enhanced removal of copper based on self-induced Fenton-like reaction constructed by electrochemistry coupled with membrane separation is disclosed. The device includes a reactor, two electrocatalytic anodes capable of generating hydroxyl radicals, an electrocatalytic cathode membrane assembly, a direct current power supply, an aeration system, an inlet pipe and an outlet pipe. The device of the present invention has a simple construction. Using this device to treat industrial wastewater containing copper complexes under specific conditions allows the decomplexation and the removal of the industrial wastewater containing the copper complexes to be simultaneously realized at a low consumption and a high efficiency. The coupling of electrochemistry with membrane separation can be achieved to protect the cathode from being contaminated by pollutants in the sewage and prolong the service life of the electrode.

Abstract: Techniques for low power voice communications include determining a time between an arrival of data for uplink transmission by a device and a scheduling request (SR) occasion, the SR occasion occurring after the arrival of the data and within an on duration of a discontinuous reception (DRX) cycle, and delaying transmission of a SR by the device during a time period that begins at the arrival of the data for uplink transmission and continues for the determined time.

Abstract: Disclosed herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.