Patents by Inventor Zhixing Wang
Zhixing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11921179Abstract: Methods, computing devices, and magnetic resonance imaging systems that improve image quality in turbo spiral echo (TSE) imaging are disclosed. With this technology, a TSE pulse sequence is generated that includes a series of radio frequency (RF) refocusing pulses to produce a corresponding series of nuclear magnetic resonance (NMR) spin echo signals. A gradient waveform including a plurality of segments is generated. The plurality of segments collectively comprise a spiral ring retraced in-out trajectory. During an interval adjacent to each of the series of RF refocusing pulses, a first gradient pulse is generated according to the gradient waveform. The first gradient pulses encode the NMR spin echo signals. An image is then constructed from digitized samples of the NMR spin echo signals obtained based at least in part on the encoding.Type: GrantFiled: April 28, 2022Date of Patent: March 5, 2024Inventors: Zhixing Wang, Steven P. Allen, Xue Feng, John P. Mugler, III, Craig H. Meyer
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Patent number: 11860258Abstract: Methods, computing devices, and MRI systems that reduce artifacts produced by Maxwell gradient terms in TSE imaging using non-rectilinear trajectories are disclosed. With this technology, a RF excitation pulse is generated to produce transverse magnetization that generates a NMR signal and a series of RF refocusing pulses to produce a corresponding series of NMR spin-echo signals. An original encoding gradient waveform comprising a non-rectilinear trajectory is modified by adjusting a portion of the original encoding gradient waveform or introducing a zero zeroth-moment waveform segment at end(s) of the original encoding gradient waveform. During an interval adjacent to each of the series of RF refocusing pulses a first gradient pulse is generated. At least one of the first gradient pulses is generated according to the modified gradient waveform. An image is constructed from generated digitized samples of the NMR spin-echo signals obtained.Type: GrantFiled: April 28, 2022Date of Patent: January 2, 2024Assignees: UNIVERSITY OF VIRGINIA PATENT FOUNDATION, SIEMENS HEALTHCARE GMBH, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICESInventors: John P. Mugler, III, Craig H. Meyer, Adrienne Campbell, Rajiv Ramasawmy, Josef Pfeuffer, Zhixing Wang, Xue Feng
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Patent number: 11846692Abstract: Training a neural network to correct motion-induced artifacts in magnetic resonance images includes acquiring motion-free magnetic resonance image (MRI) data of a target object and applying a spatial transformation matrix to the motion-free MRI data. Multiple frames of MRI data are produced having respective motion states. A Non-uniform Fast Fourier Transform (NUFFT) can be applied to generate respective k-space data sets corresponding to each of the multiple frames of MRI; the respective k-space data sets can be combined to produce a motion-corrupted k-space data set and an adjoint NUFFT can be applied to the motion-corrupted k-space data set. Updated frames of motion-corrupted MRI data can be formed. Using the updated frames of motion corrupted MRI data, a neural network can be trained that generates output frames of motion free MRI data; and the neural network can be saved.Type: GrantFiled: April 29, 2022Date of Patent: December 19, 2023Assignee: University of Virginia Patent FoundationInventors: Quan Dou, Zhixing Wang, Xue Feng, John P. Mugler, III, Craig H. Meyer
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Publication number: 20230380714Abstract: Blurring and noise artifacts in magnetic resonance (MR) images caused by off-resonant image components may be corrected with convolutional neural networks, particularly feed forward networks with skip connections. Demodulating complex blurred images with off-resonant artifacts at a selected number of frequencies forms a respective real component frame of the MR data and a respective imaginary component frame for each image. A convolutional neural network is used to de-blur the images. The network has a plurality of residual blocks with multiple convolution calculations paired with respective skip connections. The method outputs, from the convolutional neural network, a de-blurred real image frame and a de-blurred imaginary image frame of the MR data for each complex blurred image.Type: ApplicationFiled: April 21, 2023Publication date: November 30, 2023Inventors: Quan Dou, Zhixing Wang, Xue Feng, Craig H. Meyer
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Publication number: 20230342886Abstract: MR image data can be improved by using a complex de-noising convolutional neural network such as a non-blind C-DnCNN, a network for MRI denoising that leverages complex-valued data with phase information and noise level information to improve denoising performance in various settings. The proposed method achieved superior performance on both simulated and in vivo testing data compared to other algorithms. The utilization of complex-valued operations allows the network to better exploit the complex-valued MRI data and preserve the phase information. The MR image data is subject to complex de-noising operations directly and simultaneously on both real and imaginary parts of the image data. Complex and real values are also utilized for block normalization and rectified linear units applied to the noisy image data. A residual image is predicted by the C-DnCNN and a clean MR image is available for extraction.Type: ApplicationFiled: March 9, 2023Publication date: October 26, 2023Inventors: Craig H. Meyer, Quan Dou, Zhixing Wang, Xue Feng, John P. Mugler, III
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Patent number: 11747419Abstract: Systems and methods for performing ungated magnetic resonance imaging are disclosed herein. A method includes producing magnetic resonance image MRI data by scanning a target in a low magnetic field with a pulse sequence having a spiral trajectory; sampling k-space data from respective scans in the low magnetic field and receiving at least one field map data acquisition and a series of MRI data acquisitions from the respective scans; forming a field map and multiple sensitivity maps in image space from the field map data acquisition; forming target k-space data with the series of MRI data acquisitions; forming initial magnetic resonance images in the image domain by applying a Non-Uniform Fast Fourier Transform to the target k-space data; and forming reconstructed images with a low rank plus sparse (L+S) reconstruction algorithm applied to the initial magnetic resonance images.Type: GrantFiled: April 29, 2022Date of Patent: September 5, 2023Assignee: University of Virginia Patent FoundationInventors: Zhixing Wang, Xue Feng, John P. Mugler, III, Michael Salerno, Adrienne E. Campbell-Washburn, Craig H. Meyer
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Publication number: 20230272906Abstract: A two-channel burner includes a pulverized coal supply mechanism, a transition channel, an inner secondary air guide tube, an outer secondary air guide tube, a combustion stabilizing chamber, and a flow smoothing chamber. The outer secondary air guide tube, the combustion stabilizing chamber, and the flow smoothing chamber are sequentially connected to form a burner body. The pulverized coal supply mechanism passes through an interior of the burner body. The transition channel is fitted over the pulverized coal supply mechanism. The inner secondary air guide tube is disposed between the transition channel and the outer secondary air guide tube and forms an inner secondary air passage together with the transition channel, and forms an outer secondary air passage together with the outer secondary air guide tube. An outlet end of the inner secondary air guide tube is formed to have a flared opening.Type: ApplicationFiled: August 30, 2021Publication date: August 31, 2023Inventors: Fang NIU, Wei LUO, Naiji WANG, Renshan JI, Liang SHI, Xing LIANG, Yanyan GONG, Yanrong WEI, Pengzhong LIU, Lu DUAN, Xiaojiong LI, Yuhong CUI, Xing QIU, Nan JIA, Zhixing WANG, Xiangyu ZHENG, Gang LIU, Lili YAN, Xiaolei CHENG, Zhenyu LIU, Peng MIAO, Shujuan YAN, Xufang ZHANG, Shijun WANG, Meijun LI, Boxi DU, Changfang MENG, Xuewen WANG, Mingshuang CUI, Jianpeng WANG, Yongying WANG, Long CHEN, Zhi DONG, Haipeng YU, Zhe CHEN, Song ZHANG, Huiyan MA
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Publication number: 20220373630Abstract: Training a neural network to correct motion-induced artifacts in magnetic resonance images includes acquiring motion-free magnetic resonance image (MRI) data of a target object and applying a spatial transformation matrix to the motion-free MRI data. Multiple frames of MRI data are produced having respective motion states. A Non-uniform Fast Fourier Transform (NUFFT) can be applied to generate respective k-space data sets corresponding to each of the multiple frames of MRI; the respective k-space data sets can be combined to produce a motion-corrupted k-space data set and an adjoint NUFFT can be applied to the motion-corrupted k-space data set. Updated frames of motion-corrupted MRI data can be formed. Using the updated frames of motion corrupted MRI data, a neural network can be trained that generates output frames of motion free MRI data; and the neural network can be saved.Type: ApplicationFiled: April 29, 2022Publication date: November 24, 2022Inventors: Quan Dou, Zhixing Wang, Xue Feng, John P. Mugler, III, Craig H. Meyer
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Publication number: 20220373627Abstract: Methods, computing devices, and magnetic resonance imaging systems that improve image quality in turbo spiral echo (TSE) imaging are disclosed. With this technology, a TSE pulse sequence is generated that includes a series of radio frequency (RF) refocusing pulses to produce a corresponding series of nuclear magnetic resonance (NMR) spin echo signals. A gradient waveform including a plurality of segments is generated. The plurality of segments collectively comprise a spiral ring retraced in-out trajectory. During an interval adjacent to each of the series of RF refocusing pulses, a first gradient pulse is generated according to the gradient waveform. The first gradient pulses encode the NMR spin echo signals. An image is then constructed from digitized samples of the NMR spin echo signals obtained based at least in part on the encoding.Type: ApplicationFiled: April 28, 2022Publication date: November 24, 2022Applicant: University of Virginia Patent FoundationInventors: Zhixing Wang, Steven P. Allen, Xue Feng, John P. Mugler, III, Craig H. Meyer
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Publication number: 20220349970Abstract: Systems and methods for performing ungated magnetic resonance imaging are disclosed herein. A method includes producing magnetic resonance image MRI data by scanning a target in a low magnetic field with a pulse sequence having a spiral trajectory; sampling k-space data from respective scans in the low magnetic field and receiving at least one field map data acquisition and a series of MRI data acquisitions from the respective scans; forming a field map and multiple sensitivity maps in image space from the field map data acquisition; forming target k-space data with the series of MRI data acquisitions; forming initial magnetic resonance images in the image domain by applying a Non-Uniform Fast Fourier Transform to the target k-space data; and forming reconstructed images with a low rank plus sparse (L+S) reconstruction algorithm applied to the initial magnetic resonance images.Type: ApplicationFiled: April 29, 2022Publication date: November 3, 2022Inventors: Zhixing Wang, Xue Feng, John P. Mugler, III, Michael Salerno, Adrienne E. Campbell-Washburn, Craig H. Meyer
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Publication number: 20020012431Abstract: This system segments and converts a cryptograph key into two digital optical signals with amplitudes, wavelengths, and initial phases, and an initial aberration (optical path length difference) at a point P where the two digital optical signals meet.Type: ApplicationFiled: June 19, 2001Publication date: January 31, 2002Inventor: Zhixing Wang