Abstract: A method of preparing an amorphous, low-melting-point polyester hot-melt adhesive is disclosed. The method includes the steps of: 1) esterifying terephthalic acid, isophthalic acid and an aliphatic dicarboxylic acid with ethylene glycol and a C3-C6 dial in a presence of an esterification catalyst; 2) adding a stabilizer, a polycondensation catalyst and an antioxidant to a product from step 1) and lowering the pressure to perform a polycondensation reaction which results in a polyester having a melting point of lower than 120° C. The polyester hot-melt adhesive of the invention assumes a transparent state with no crystallization both in normal-temperature and high-temperature conditions and has a high flowability and an excellent wettability in low-temperature applications.