Patents by Inventor Zhiyan Yu

Zhiyan Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11939386
    Abstract: Disclosed are a new AXL-targeting monoclonal antibody and antibody-drug conjugate. Also disclosed is a method for preparing said antibody and antibody-drug conjugate. The AXL antibody of the present invention can bind with purified human AXL protein and multiple AXL on tumor cell surface with high effectiveness and high specificity. Said humanized antibody also has high affinity and low immunogenicity. Said AXL antibody-drug conjugate has markable performance against tumors having high AXL expression.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 26, 2024
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Ke Yu, Jingkang Shen, Tao Meng, Jinpeng Pei, Lanping Ma, Xin Wang, Rui Jin, Zhiyan Du, Lin Chen, Ting Yu, Yongliang Zhang
  • Patent number: 11937920
    Abstract: Intelligent real-time blood glucose monitoring system and method based on cloud big data is disclosed. The system includes an implantable dynamic glucose sensor, a smart phone, a blood glucose monitoring software application installed on the smart phone, a finger blood glucose meter, and a big data cloud server. By processing historical blood glucose measurement data of a user stored in the cloud, the monitoring system effectively corrects and influences signal differences produced by individual users so as to ensure the validity and accuracy of measurement signals during sensor operation.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: March 26, 2024
    Assignee: MICROTECH MEDICAL (HANGZHOU) CO., LTD.
    Inventors: Fei Yu, Zhiyan Chen
  • Patent number: 10252353
    Abstract: An apparatus and method for processing anode plate for electrolysis, the apparatus includes a transverse transmission device (3) for transmitting the anode plate in a transverse direction; a plate-flattening and thickness-measuring device (4) for flattening the anode plate and measuring a thickness of the anode plate; a hanger bottom milling device (6) configured to mill a bottom surface of a hanger of the anode plate, disposed at a first side of the transverse transmission device (3) and positioned downstream of the plate-flattening and thickness-measuring device (4) in the transverse direction; and a hanger side milling device (5) configured to mill a side surface of the hanger of the anode plate, disposed at a second side of the transverse transmission device (3) and positioned downstream of the plate-flattening and thickness-measuring device (4) in the transverse direction.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: April 9, 2019
    Assignee: JIANGXI NERIN EQUIPMENT CO., LTD.
    Inventors: Aimin Deng, Zhiyan Yu, Xiaoguang Shao
  • Patent number: 9356213
    Abstract: A manufacturing method of a light-emitting diode device. The light-emitting diode device comprises: a substrate (1); an epitaxial layer at one side of the substrate (1) and comprising an N-type layer (2), a P-type layer (4), and an active layer (3) between the N-type layer (2) and the P-type layer (4); an N-type electrode (5); a P-type electrode (7); an adhesive layer (8); and a patterned substrate (9). The light-emitting diode device further comprises an insulating layer (6) between the N-type electrode (5) and the P-type electrode (7), the insulating layer (6) electrically insulating the N-type electrode (5) and the P-type electrode (7). In the manufacturing method thereof, light-emitting efficiency and luminous efficiency of the light-emitting diode device can be improved, wiring is easier as compared with conventional chips, and the manufacturing process can be optimized.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: May 31, 2016
    Assignee: WUXI CHINA RESOURCES HUAJING MICROELECTRONICS CO., LTD.
    Inventors: Lei Wang, Guoqi Li, Zhiyan Yu, Rongsheng Pu
  • Publication number: 20160013386
    Abstract: A manufacturing method of a light-emitting diode device. The light-emitting diode device comprises: a substrate (1); an epitaxial layer at one side of the substrate (1) and comprising an N-type layer (2), a P-type layer (4), and an active layer (3) between the N-type layer (2) and the P-type layer (4); an N-type electrode (5); a P-type electrode (7); an adhesive layer (8); and a patterned substrate (9). The light-emitting diode device further comprises an insulating layer (6) between the N-type electrode (5) and the P-type electrode (7), the insulating layer (6) electrically insulating the N-type electrode (5) and the P-type electrode (7). In the manufacturing method thereof, light-emitting efficiency and luminous efficiency of the light-emitting diode device can be improved, wiring is easier as compared with conventional chips, and the manufacturing process can be optimized.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Inventors: Lei Wang, Guoqi Li, Zhiyan Yu, Rongsheng Pu
  • Patent number: 9172002
    Abstract: A light-emitting diode device and a manufacturing method thereof. The light-emitting diode device includes: a substrate (1); an epitaxial layer at one side of the substrate (1) and including an N-type layer (2), a P-type layer (4), and an active layer (3) between the N-type layer (2) and the P-type layer (4); an N-type electrode (5); a P-type electrode (7); an adhesive layer (8); and a patterned substrate (9). The light-emitting diode device further includes an insulating layer (6) between the N-type electrode (5) and the P-type electrode (7), the insulating layer (6) electrically insulating the N-type electrode (5) and the P-type electrode (7). In the light-emitting diode device and the manufacturing method thereof, light-emitting efficiency and luminous efficiency of the light-emitting diode device can be improved, wiring is easier as compared with conventional chips, and the manufacturing process can be optimized.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: October 27, 2015
    Assignee: Wuxi China Resources Huajing Microelectronic Co., Ltd.
    Inventors: Lei Wang, Guoqi Li, Zhiyan Yu, Rongsheng Pu
  • Publication number: 20140367697
    Abstract: A light-emitting diode device and a manufacturing method thereof. The light-emitting diode device comprises: a substrate (1); an epitaxial layer at one side of the substrate (1) and comprising an N-type layer (2), a P-type layer (4), and an active layer (3) between the N-type layer (2) and the P-type layer (4); an N-type electrode (5); a P-type electrode (7); an adhesive layer (8); and a patterned substrate (9). The light-emitting diode device further comprises an insulating layer (6) between the N-type electrode (5) and the P-type electrode (7), the insulating layer (6) electrically insulating the N-type electrode (5) and the P-type electrode (7). In the light-emitting diode device and the manufacturing method thereof, light-emitting efficiency and luminous efficiency of the light-emitting diode device can be improved, wiring is easier as compared with conventional chips, and the manufacturing process can be optimized.
    Type: Application
    Filed: December 3, 2012
    Publication date: December 18, 2014
    Inventors: Lei Wang, Guoqi Li, Zhiyan Yu, Rongsheng Pu
  • Publication number: 20140331732
    Abstract: An apparatus and method for processing anode plate for electrolysis, the apparatus includes a transverse transmission device (3) for transmitting the anode plate in a transverse direction; a plate-flattening and thickness-measuring device (4) for flattening the anode plate and measuring a thickness of the anode plate; a hanger bottom milling device (5) configured to mill a bottom surface of a hanger of the anode plate, disposed at a first side of the transverse transmission device (3) and positioned downstream of the plate-flattening and thickness- measuring device (4) in the transverse direction; and a hanger side milling device (6) configured to mill a side surface of the hanger of the anode plate, disposed at a second side of the transverse transmission device (3) and positioned downstream of the plate-flattening and thickness-measuring device (4) in the transverse direction.
    Type: Application
    Filed: October 24, 2012
    Publication date: November 13, 2014
    Inventors: Aimin Deng, Zhiyan Yu, Xiaoguang Shao