Abstract: An agent for inhibiting binding of transferrin receptor to SARS-CoV-2 spike protein or an anti-SARS-CoV-2 medicament is provided, where active pharmaceutical ingredients of the agent or the medicament include interference peptides, and the interference peptides include: SL8, FG8, DL12, RK4, SD6, HF7, and/or QK8.

Abstract: The present disclosure provides a thermal-stress-pore pressure coupled electromagnetic loading triaxial Hopkinson bar system and test method, the system mainly consists of an electromagnetic pulse generation system, a servo-controlled axial pressure loading system, a servo-controlled confining pressure loading system, a thermal control system, a pore pressure loading system, a bar system, and a data monitoring and acquisition system. Based on the conventional Hopkinson bar, the present disclosure creatively introduces a real-time loading and control system for confining pressure, thermal, and pore pressure, aiming to solve the technical problem that the existing test apparatus cannot be used to study dynamic response of deep rock mass under the coupling effect of thermal-stress-pore pressure and dynamic disturbance during dynamic impact loading.

Abstract: A uniaxial bidirectional synchronous control electromagnetic loaded dynamic shear test system and method, a test apparatus thereof including a support platform, a loading bar system, an electromagnetic pulse generation system, a servo-controlled normal pressure loading system, and a data monitoring and acquisition system. The test apparatus can be used to conduct a dynamic shear test research on a rock-like material under a constant normal pressure close to an actual operating condition, and can also be applied to carry out dynamic shear tests on intact rock-like test specimens in various sizes or jointed rock-like test specimens containing a single structural surface to study dynamic shear mechanical property and shear failure behavior under strain rate of 101?103 s?1, thereby providing an important theoretical and technical support for the design, construction, protection, and safety and stability evaluation of geotechnical engineering, structural engineering.

Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).

Abstract: A system for the in-situ retained coring of a rock sample has a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence. The coring module (100) includes a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) includes a rock core sample retaining compartment. The driving module includes a coring drill machine that has a drill machine outer cylinder unlocking mechanism. The rock core drilling tool includes a coring drill tool, a core catcher (11), and an inner core pipe (12). The coring drill tool has an outer core pipe (13) and a hollow drill bit (14). The rock core sample retaining compartment has an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229).

Abstract: A coring device has core drilling tool, a core catcher, a rock core barrel, a drilling machine outer cylinder, a flap valve and an inner rod for pulling the rock core barrel. The core catcher is provided inside the lower end of the rock core barrel. The core drilling tool includes an outer core tube and a hollow drill bit. The upper end of the outer core tube is connected to the lower end of the drilling machine outer cylinder. The lower end of the outer core tube is connected to the drill bit. The lower end of the inner rod protrudes into the rock core barrel and is movable axially by a certain distance relative to the rock core barrel. The flap valve includes a valve seat and a sealing flap. The valve seat is coaxially mounted on the inner wall of the drilling machine outer cylinder.

Abstract: A fidelity retaining type coring device for a rock sample, comprising a rock core drilling tool, a rock core sample storage barrel, and a rock core sample fidelity retaining cabin.

Abstract: The present disclosure provides a dynamic true triaxial electromagnetic Hopkinson bar system and testing method, the method including: firstly, before applying a static prestress and an impact load, recording and storing complete ultrasonic signals in the directions X, Y, and Z without application of the static prestress and the impact load; secondly, applying the static prestress; thirdly, recording and storing complete ultrasonic signals in the directions X, Y, and Z under the static prestress; fourthly, applying the impact load, and utilizing an triaxial and six-directional synchronous-coordinated-control electromagnetic loading system to apply a dynamic impact load to a test specimen; and fifthly, after completing the dynamic impact loading test, recording and storing once again complete ultrasonic signals in the directions X, Y, and Z without releasing the static prestress after application of the static prestress and the dynamic impact load.

Abstract: The present disclosure provides use of transferrin, a transferrin receptor and an antibody thereof in the preparation of an anti-SARS-CoV-2 drug. Use of the transferrin, the transferrin receptor or the transferrin receptor antibody in the preparation of an anti-SARS-CoV-2 drug is provided. Both surface plasmon resonance (SPR) and immunofluorescence confirm that the SARS-CoV-2 binds to the transferrin receptor through SARS-CoV-2 spike protein; the transferrin and/or the transferrin receptor antibody competitively bind(s) to the transferrin receptor of the body, or the transferrin receptor competitively binds to a site of the SARS-CoV-2 to inhibit binding of the SARS-CoV-2 to the transferrin receptor of the body; thus, the opportunity that the SARS-CoV-2 infects cells is blocked, and the antiviral effect of the body is realized.

Abstract: An agent for inhibiting binding of transferrin receptor to SARS-CoV-2 spike protein or an anti-SARS-CoV-2 medicament is provided, where active pharmaceutical ingredients of the agent or the medicament include interference peptides, and the interference peptides include: SL8, FG8, DL12, RK4, SD6, HF7, and/or QK8.

Abstract: A coring device has core drilling tool, a core catcher, a rock core barrel, a drilling machine outer cylinder, a flap valve and an inner rod for pulling the rock core barrel. The core catcher is provided inside the lower end of the rock core barrel. The core drilling tool includes an outer core tube and a hollow drill bit. The upper end of the outer core tube is connected to the lower end of the drilling machine outer cylinder. The lower end of the outer core tube is connected to the drill bit. The lower end of the inner rod protrudes into the rock core barrel and is movable axially by a certain distance relative to the rock core barrel. The flap valve includes a valve seat and a sealing flap. The valve seat is coaxially mounted on the inner wall of the drilling machine outer cylinder.

Abstract: A fidelity retaining type coring device for a rock sample, comprising a rock core drilling tool, a rock core sample storage barrel, and a rock core sample fidelity retaining cabin.

Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).

Abstract: Disclosed is a system for the in-situ retained coring of a rock sample, the system comprising a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence, wherein the coring module (100) comprises a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) comprises a rock core sample retaining compartment; the driving module comprises a coring drill machine that comprises a drill machine outer cylinder unlocking mechanism; the rock core drilling tool comprises a coring drill tool, a core catcher (11), and an inner core pipe (12); the coring drill tool comprises an outer core pipe (13) and a hollow drill bit (14); and the rock core sample retaining compartment comprises an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229). The system is conducive to retaining the state of a rock core in an in-situ environment, and can improve the drilling rate and improve the coring efficiency.

Abstract: The present disclosure provides a thermal-stress-pore pressure coupled electromagnetic loading triaxial Hopkinson bar system and test method, the system mainly consists of an electromagnetic pulse generation system, a servo-controlled axial pressure loading system, a servo-controlled confining pressure loading system, a thermal control system, a pore pressure loading system, a bar system, and a data monitoring and acquisition system. Based on the conventional Hopkinson bar, the present disclosure creatively introduces a real-time loading and control system for confining pressure, thermal, and pore pressure, aiming to solve the technical problem that the existing test apparatus cannot be used to study dynamic response of deep rock mass under the coupling effect of thermal-stress-pore pressure and dynamic disturbance during dynamic impact loading.

Abstract: A uniaxial bidirectional synchronous control electromagnetic loaded dynamic shear test system and method, a test apparatus thereof including a support platform, a loading bar system, an electromagnetic pulse generation system, a servo-controlled normal pressure loading system, and a data monitoring and acquisition system. The test apparatus can be used to conduct a dynamic shear test research on a rock-like material under a constant normal pressure close to an actual operating condition, and can also be applied to carry out dynamic shear tests on intact rock-like test specimens in various sizes or jointed rock-like test specimens containing a single structural surface to study dynamic shear mechanical property and shear failure behavior under strain rate of 101?103 s?1, thereby providing an important theoretical and technical support for the design, construction, protection, and safety and stability evaluation of geotechnical engineering, structural engineering.

Abstract: The present disclosure provides a dynamic true triaxial electromagnetic Hopkinson bar system and testing method, the method including: firstly, before applying a static prestress and an impact load, recording and storing complete ultrasonic signals in the directions X, Y, and Z without application of the static prestress and the impact load; secondly, applying the static prestress; thirdly, recording and storing complete ultrasonic signals in the directions X, Y, and Z under the static prestress; fourthly, applying the impact load, and utilizing an triaxial and six-directional synchronous-coordinated-control electromagnetic loading system to apply a dynamic impact load to a test specimen; and fifthly, after completing the dynamic impact loading test, recording and storing once again complete ultrasonic signals in the directions X, Y, and Z without releasing the static prestress after application of the static prestress and the dynamic impact load.