Abstract: A color matching observation box for an LED standard light source comprises a box body, wherein an opening is formed in one side of the box body, an observation chamber is formed by the internal space of the box body, and a standard light source is disposed at the top of the observation chamber and comprises multiple lamp beads; and each of the lamp beads comprises a purple LED chip with a wavelength of 410 nm-430 nm, a blue LED chip with a wavelength of 440 nm-460 nm, and hybrid fluorescent powder. The color matching observation box may be provided with two groups of fluorescent lamps and one group of UV lamps, wherein the UV lamps can be used separately or in combination with other light sources.

Abstract: The embodiments of the present disclosure relate to the technical field of computers. Disclosed are a method and apparatus for information fusion, a method and apparatus for data communication, and an electronic device and a non-transitory computer-readable storage medium. The method for information fusion includes: in response to that a communication triggering condition is met, acquiring a local parameter of each of workers in a distributed training system, where the communication triggering condition is that all key nodes complete tasks of the current round of training; selecting N key nodes participating in the next round of training, and fusing local parameters of the N key nodes to obtain a global parameter; and sending the global parameter to each of the workers, and sending a training command to the key nodes to the key nodes execute tasks of next round of training based on the global parameter.

Abstract: An nGraph-based graphics processing unit (GPU) backend distributed training method and system, a computer-readable storage medium, and an electronic device. The method includes: receiving a training request, and obtaining corresponding training data; obtaining a Nvidia® Collective multi-GPU Communication Library (NCCL) file by means of a system path of the NCCL file linked to an nGraph framework; invoking an NCCL communication interface configuration according to the training request to obtain a training model, the NCCL communication interface is an NCCL file-based communication operation interface located at a GPU backend of the nGraph framework; and performing GPU backend training on the training data using the training model. The present application can satisfy an urgent need of a user for performing neural network distributed training on the basis of an nGraph GPU backend, thus further improving the performance of deep learning network training.

Abstract: An nGraph-based graphics processing unit (GPU) backend distributed training method and system, a computer-readable storage medium, and an electronic device. The method includes: receiving a training request, and obtaining corresponding training data; obtaining a Nvidia® Collective multi-GPU Communication Library (NCCL) file by means of a system path of the NCCL file linked to an nGraph framework; invoking an NCCL communication interface configuration according to the training request to obtain a training model, the NCCL communication interface is an NCCL file-based communication operation interface located at a GPU backend of the nGraph framework; and performing GPU backend training on the training data using the training model. The present application can satisfy an urgent need of a user for performing neural network distributed training on the basis of an nGraph GPU backend, thus further improving the performance of deep learning network training.

Abstract: Identity and access management may update and remediation may be performed dynamically. Historical user behavior data may be obtained. An account specific baseline based on the historical user behavior data may be generated. An access request may be received from a current user. Current user behavior data associated with a current user may be obtained. The current user behavior data may be compared to the account specific baseline. It may be determined whether the current user behavior data satisfies the account specific baseline. If the current user behavior data satisfies the account specific baseline, an access may be granted to the current user. If the current user behavior data does not satisfy the account specific baseline, access may be denied to the current user.

Abstract: Identity and access management may update and remediation may be performed dynamically. Historical user behavior data may be obtained. An account specific baseline based on the historical user behavior data may be generated. An access request may be received from a current user. Current user behavior data associated with a current user may be obtained. The current user behavior data may be compared to the account specific baseline. It may be determined whether the current user behavior data satisfies the account specific baseline. If the current user behavior data satisfies the account specific baseline, an access may be granted to the current user. If the current user behavior data does not satisfy the account specific baseline, access may be denied to the current user.

Abstract: A hair straightener heating element comprises: a base, a working plate, a heating sheet, a thermal insulation sheet, and a silica gel pad. The base is provided with an accommodation groove thereon. The silica gel pad is arranged in the accommodation groove. The thermal insulation sheet is fitted into the silica gel pad. The heating sheet is arranged on the thermal insulation sheet. The working plate has an inverted “U” shape, and cooperates with the base to sandwich the heating sheet, the thermal insulation sheet and the silica gel pad between the working plate and the base. The heating sheet is attached and matches a bottom surface of the working plate. The heating element separates a frame and a working plate into two devices, and provides a good contact between a heating sheet and the working plate so as to be isolated from the frame. The heating sheet immediately conducts heat to the working plate, and rapidly raises the temperature of the working plate, thereby enhancing a heating rate.

Abstract: The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising CTL epitopes PSMA288-297 and PRAME425-433, or a cross-reactive analogue. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.

Abstract: The invention disclosed herein is directed to methods of identifying a polypeptide suitable for epitope liberation including, for example, the steps of identifying an epitope of interest; providing a substrate polypeptide sequence including the epitope, wherein the substrate polypeptide permits processing by a proteasome; contacting the substrate polypeptide with a composition including the proteasome, under conditions that support processing of the substrate polypeptide by the proteasome; and assaying for liberation of the epitope. The invention further relates to vectors including a housekeeping epitope expression cassette. The housekeeping epitope(s) can be derived from a target-associated antigen, and the housekeeping epitope can be liberatable, that is capable of liberation, from a translation product of the cassette by immunoproteasome processing. The invention also relates to a method of activating a T cell comprising contacting a substrate polypeptide with an APC and contacting the APC with a T cell.

Abstract: The invention disclosed herein is directed to methods of identifying a polypeptide suitable for epitope liberation including, for example, the steps of identifying an epitope of interest; providing a substrate polypeptide sequence including the epitope, wherein the substrate polypeptide permits processing by a proteasome; contacting the substrate polypeptide with a composition including the proteasome, under conditions that support processing of the substrate polypeptide by the proteasome; and assaying for liberation of the epitope. The invention further relates to vectors including a housekeeping epitope expression cassette. The invention relates to epitope cluster regions and to vectors including epitope cluster regions. The invention also relates to a method of activating a T cell comprising contacting a substrate polypeptide with an APC and contacting the APC with a T cell.

Abstract: The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.

Abstract: The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.

Abstract: The instant disclosure relates to methods for treating a cancer patient with an active immunotherapeutic, wherein the methods include assessing a patient's pre-existing immunoreactivity to at least one target antigen, choosing an immunotherapeutic regimen based on the level of pre-existing immunoreactivity, and administering an active immunotherapeutic according to the regimen.

Abstract: The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising CTL epitopes PSMA288-297 and PRAME425-433, or a cross-reactive analogue. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.