Abstract: The present disclosure provides compounds and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.

Abstract: Disclosed is a lighting control method and a lighting control device for a light source having LEDs, and a lighting device and includes acquiring the number of LEDs and a control curve for controlling changes in brightness and color of the light emitted from each LED over time, the control curve defines the same brightness cycle and color cycle for each LED, the brightness cycle indicates a brightness period and a brightness curve of the change in brightness over time within each period, determining a time offset on the control curve according to the number of LEDs and the brightness change period, determining the starting timings of the remaining LEDs on the control curve according to the starting timing of the first LED and the time offset, and controlling each LED from the starting timing on the control curve, to emit light according to the brightness and color determined.

Abstract: A method for controlling heating of an electric drive system of a vehicle, the electric drive system includes a motor controller and a motor, and the method includes: determining that the vehicle is in a travelling state; obtaining a rotation speed value and a torque control value of a motor and obtaining a carrier instruction value of a motor controller when receiving a heating instruction; obtaining a first current instruction value based on the rotation speed value and the torque control value, and obtaining a second current instruction value based on the torque control value and the first current instruction value; adjusting a control signal of the motor controller based on at least one of the second current instruction value or a second carrier frequency; and controlling the motor to operate based on the adjusted control signal, so that the electric drive system generates heat.

Abstract: Disclosed are methods and systems for generating three-dimensional reconstructions of environments. A system, for example, may include a housing having an image sensor directed in a first direction and a distance sensor directed in a second direction and a control unit including a processor and a memory storing instructions. The processor may be configured to execute the instructions to: generate a first 3D model of an environment; generate a plurality of revolved 3D models by revolving the first 3D model relative to the image sensor to a plurality of positions within a predetermined angular range; match a set of distance values to one of the revolved 3D models; determine an angular position of the second direction relative to the first direction; and generate a 3D reconstruction of the environment.

Abstract: The present invention provides a cochlear outer hair cell (OHC) regenerated by ectopic joint overexpression of Atoh1 and Ikzf2 and an application thereof. Specifically, the present invention provides an active ingredient combination capable of being used for regenerating a cochlear OHC, and a use thereof. The active ingredient combination comprises an Ikzf2 protein and an Atoh1 protein; and after the active ingredient combination is administered to a subject suffering from hearing impairment related to cochlear OHC degeneration and/or injury, hearing impairment can be alleviated by regenerating an OHC-like cell. A new method is provided for clinical treatment of hearing impairment.

Abstract: The present disclosure provides compounds and pharmaceutically acceptable salt thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.

Abstract: The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.

Abstract: Disclosed in the present application are a paging method and a base station. In the technical solution of the present application, the base station receives a paging message sent by a MME, the paging message carrying auxiliary information, the auxiliary information being used for indicating a paging range and/or paging times, and the paging range comprising a cell and/or base station recommended to a target terminal of the paging message; and the base station sends the paging message according to the auxiliary information.

Abstract: Bioelectrochemical systems (BES) having configurations with spiral wound structures and with frame-and-plate structures are provided. Systems may allow for production of an electrical current that is at least partially generated by anodophilic microorganisms connected directly or indirectly to an electrode. A spiral wound or frame-and-plate type bioelectrochemical system may include an anolyte influent point, a catholyte influent point, electrodes, ion selective membranes, mesh separators, gas collection devices, an exterior containment vessel, and one or more external electrical devices.

Abstract: The present invention discloses a virtual community system for an elderly health service based on a big data technology, including an information obtaining module for obtaining personal information of elderly people, a management platform for processing user information, a recommendation module for sending recommended information to a user, and a backend terminal for providing a manual service. The information obtaining module includes a locator, configured to obtain the elderly people's position information to prevent the elderly people from getting lost; and a health bracelet, configured to detect the elderly people's heart rate and blood pressure which directly reflect the elderly people's physical condition. The present invention is designed to meet an existing need. One-time treatment for a lifetime medical service is implemented based on existing medical data and personal data acquired by health equipment.

Abstract: The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.

Abstract: The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.

Abstract: The present invention relates to the unexpected discovery of systems for capturing carbon dioxide and producing hydrogen gas. In certain embodiments, the system treats wastewater. In certain embodiments, the system captures and sequesters CO2 as carbonate salts.

Abstract: Described herein are methods for using solid electrodes as an alternative source or sink of electrons to regulate the redox potential of mixed culture anaerobic reactors, so tunable fermentation products can be generated.

Abstract: Disclosed in the present application are a paging method and a base station. In the technical solution of the present application, the base station receives a paging message sent by a MME, the paging message carrying auxiliary information, the auxiliary information being used for indicating a paging range and/or paging times, and the paging range comprising a cell and/or base station recommended to a target terminal of the paging message; and the base station sends the paging message according to the auxiliary information.

Abstract: A bioelectrochemical system device may be used to enhance groundwater pollutant chemical removal or degradation. Such a bioelectrochemical system may be inserted into the environment to be remediated through a variety of techniques, such as through insertion into wells or other access points, trench insertion, direct insertion, borehole insertion, or combinations thereof. In some aspects, the bioelectrochemical system device may have a hollow-tube configuration with an outer ring anode and inner ring cathode. In further aspects, the bioelectrochemical system device may have a modular form that can be combined with multiple other modules such one or more bioelectrochemical system devices.

Abstract: The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.

Abstract: A method for testing a display panel includes: applying a first level signal to a first sub-pixel and a third sub-pixel of a first pixel unit and applying a second level signal to a second sub-pixel of the first pixel unit; applying the second level signal to a first sub-pixel and a third sub-pixel of a second pixel unit and applying the first level signal to a second sub-pixel of the second pixel unit; and detecting a short circuit between adjacent sub-pixels. The first level signal has a voltage polarity opposite to a voltage polarity of the second level signal. Therefore, it is ensured that any two adjacent sub-pixels have opposite voltage polarities when the short circuit between adjacent sub-pixels of the display panel is detected. The method also provides improved testing abilities to detect an open circuit in a sub-pixel.

Abstract: Bioelectrochemical systems (BES) having configurations with spiral wound structures and with frame-and-plate structures are provided. Systems may allow for production of an electrical current that is at least partially generated by anodophilic microorganisms connected directly or indirectly to an electrode. A spiral wound or frame-and-plate type bioelectrochemical system may include an anolyte influent point, a catholyte influent point, electrodes, ion selective membranes, mesh separators, gas collection devices, an exterior containment vessel, and one or more external electrical devices.

Abstract: Bioelectrochemical systems (BES) having configurations with spiral wound structures and with frame-and-plate structures are provided. Systems may allow for production of an electrical current that is at least partially generated by microorganisms connected directly or indirectly to an electrode. A spiral wound or frame-and-plate type bioelectrochemical system that may be used for energy or chemical production, and/or desalination may include an anolyte influent point, a catholyte influent point, electrodes, ion selective membranes, mesh separators, gas collection devices, an exterior containment vessel, and one or more external electrical devices.