Patents by Inventor Zhiyuan Li

Zhiyuan Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210111567
    Abstract: The invention provides a voltage balancing system for voltage balancing. The voltage balancing system includes an analog front end arranged in parallel with the cell group, a micro control unit communicating with the analog front end, a communication isolation module connected between the analog front end and the micro control unit, and a balancing module. The input of the balancing module is connected to the cell group to input the total voltage of the cell group. The output of the balancing module is connected to the micro control unit and the communication isolation module to output the operating voltage of the micro control unit and the communication isolation module.
    Type: Application
    Filed: September 30, 2020
    Publication date: April 15, 2021
    Inventors: Huage Wang, Baoan Li, Xian Zhuang, Chuanjun Liu, Zhiyuan Li
  • Patent number: 10957222
    Abstract: Provided are a normal fault simulation experiment device with an adjustable angle and an adjustable fracture initiation position and a method of using the same, which relate to the technical field of normal fault simulation experiments. The device includes a base, a column, a baffle plate, a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a front baffle plate and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are disposed below an experimental body, the upper loading apparatus and the upper angle adjusting apparatus are disposed above the experimental body, the transparent side plate is disposed on a rear side surface of the experimental body, and a plurality of strip-shaped front baffle plates are disposed on a front side surface of the experimental body.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: March 23, 2021
    Assignee: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Shaojie Chen, Zhiyuan Li, Xinyuan Zhang, Zhiguo Xia, Tianqi Jiang, Jian Cui, Dawei Yin
  • Publication number: 20210049933
    Abstract: Provided are a normal fault simulation experiment device with an adjustable angle and an adjustable fracture initiation position and a method of using the same, which relate to the technical field of normal fault simulation experiments. The device includes a base, a column, a baffle plate, a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a front baffle plate and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are disposed below an experimental body, the upper loading apparatus and the upper angle adjusting apparatus are disposed above the experimental body, the transparent side plate is disposed on a rear side surface of the experimental body, and a plurality of strip-shaped front baffle plates are disposed on a front side surface of the experimental body.
    Type: Application
    Filed: April 29, 2019
    Publication date: February 18, 2021
    Inventors: Shaojie CHEN, Zhiyuan LI, Xinyuan ZHANG, Zhiguo XIA, Tianqi JIANG, Jian CUI, Dawei YIN
  • Publication number: 20210049934
    Abstract: A coal measures fault formation simulation experimental device and a normal and reverse fault simulation experiment method relate to the field of similar material simulation experiment technology. The device includes a hydraulic lifting apparatus, a lower angle adjusting apparatus, a push rod apparatus, an upper loading apparatus, an upper angle adjusting apparatus, a lateral loading apparatus and a transparent side plate. The hydraulic lifting apparatus and the lower angle adjusting apparatus are below the experimental body, the upper loading apparatus and the upper angle adjusting apparatus are above the experimental body, the transparent side plate is disposed at a rear side surface of the experimental body, and the lateral loading apparatus is disposed at an end face of the experimental body.
    Type: Application
    Filed: April 29, 2019
    Publication date: February 18, 2021
    Inventors: Shaojie CHEN, Zhiyuan LI, Xinyuan ZHANG, Zhiguo XIA, Tianqi JIANG, Jian CUI, Dawei YIN
  • Publication number: 20210040850
    Abstract: Provided is a filling mining method for a fully-mechanized top coal caving working face, which relates to the field of mining engineering technologies. The method solves the technical problems of roof control of the fully-mechanized top coal caving working face and a large ground deformation of top coal caving mining.
    Type: Application
    Filed: December 25, 2018
    Publication date: February 11, 2021
    Inventors: Shaojie CHEN, Zhaowen DU, Zhiguo XIA, Zhen ZHANG, Bing CHEN, Zhiyuan LI, Yong JIAN
  • Publication number: 20200339699
    Abstract: The invention relates to a novel antibody and an antibody fragment thereof specifically binding to a B-cell maturation antigen (BCMA), and particularly relates to a fully humanized single-chain variable fragment (scFv). The invention further relates to a nucleic acid encoding the antibody, a vector, and a host cell expressing the nucleic acid. Furthermore, the invention also relates to a composition containing the antibody described herein, and use thereof in treatment and diagnosis.
    Type: Application
    Filed: February 1, 2019
    Publication date: October 29, 2020
    Inventors: Zhiyuan LI, Tianhang ZHAI, Shuaixiang ZHOU, Dechao YU
  • Publication number: 20200233012
    Abstract: An apparatus and method for measuring a structural angular acceleration based on dynamic centrifugal force measurement belong to the technical field of angular acceleration measurement. The apparatus has a solid ball. The solid ball can move freely along the radial direction of the outer wall packaging hood. The elastic block is used as a stress base. A rod for lateral limit and connection is used for connecting the rigid block and a pulley and limiting the displacement of solid ball so that the solid ball can only move longitudinally along the apparatus. The rigid block can move freely due to the pulley. Measurement of a transient angular acceleration is converted into dynamic measurement of the centrifugal force of the solid ball. Through the above design, the dynamic angular acceleration of the structure caused by dynamic load can be relatively accurately calculated.
    Type: Application
    Filed: July 5, 2018
    Publication date: July 23, 2020
    Inventors: Jianbo LI, Kai YANG, Shiyun XIAO, Runyu MEI, Zhiqiang HU, Lei ZHOU, Jun LIU, Zhiyuan LI
  • Publication number: 20200157763
    Abstract: A measuring device and method for horizontal dynamic impedance of specified foundation depth based on differential response analysis of pulse excitation. The measuring method is realized based on the measuring device. Two rigid piles with different lengths are embedded into different foundation depths. Motion characteristics of the two rigid piles in the process of collision impact with the outside are different under the same pulse excitation. Dynamic impedance of specified foundation depth is deduced from the formula according to the differential response. Single-degree-of-freedom oscillators are arranged on the pile heads of the two piles, and strain gauges are arranged on the bottoms of the single-degree-of-freedom oscillators to obtain stress states of the single-degree-of-freedom oscillators, thereby calculating the relative displacements of the single-degree-of-freedom oscillators. This is simple in structure, reliable in measurement and convenient in data collection and processing.
    Type: Application
    Filed: March 19, 2018
    Publication date: May 21, 2020
    Inventors: Jianbo LI, Weihong LIU, Zhiyuan LI, Gao LIN
  • Publication number: 20200002400
    Abstract: Provided are a chimeric antigen receptor targeting CD20 antigen and a preparation method thereof. The extracellular antigen binding domain of the chimeric antigen receptor includes an antibody heavy chain variable region shown in SEQ ID NO: 7 or 9 or 33 and an antibody light chain variable region shown in SEQ ID NO: 11 or 13 or 35, and is capable of killing tumor cells.
    Type: Application
    Filed: February 8, 2018
    Publication date: January 2, 2020
    Applicants: CELLULAR BIOMEDICINE GROUP (SHANGHAI) LTD., CELLULAR BIOMEDICINE GROUP (WUXI) LTD.
    Inventors: Yihong YAO, Jiaqi HUANG, Shigui ZHU, Wei ZHU, Xin YAO, Zhiyuan LI, Li ZHANG, Lin ZHU, Anyun MA, Yutian WEI, Yanfeng LI, Qingxia WANG, Jiaping HE
  • Patent number: 10400567
    Abstract: The invention discloses a pipeline descaling and rock stratum fracturing device based on electro-hydraulic pulse shock waves, comprising a ground low-voltage control device, a transmission cable and an electro-hydraulic pulse shock wave transmitter.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: September 3, 2019
    Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Yi Liu, Fuchang Lin, Yuan Pan, Qin Zhang, Hua Li, Zhiyuan Li, Siwei Liu
  • Publication number: 20190041377
    Abstract: The present disclosure discloses a method for measuring a mudflat elevation based on remotely sensed water content, comprising steps of: measuring a spectral value of a soil surface in a mudflat area using a full-band spectrometer, analyzing a relationship between the spectral value and a soil water content of the mudflat area; building a remotely sensed water content retrieval model using a statistical correlation method; selecting a water sensitive waveband in the remote sensing data, and retrieving the soil water content of the mudflat area; analyzing a relationship between the soil water content and the mudflat likewise using the statistical correlation method; building a relational model between the mudflat water content and an elevation, and applying the model to a satellite image to obtain the mudflat elevation.
    Type: Application
    Filed: October 7, 2018
    Publication date: February 7, 2019
    Inventors: HUAN LI, XIAOYAN ZHANG, ZHIYUAN LI, ZIJIE YANG
  • Publication number: 20190017362
    Abstract: The invention discloses a pipeline descaling and rock stratum fracturing device based on electro-hydraulic pulse shock waves, comprising a ground low-voltage control device, a transmission cable and an electro-hydraulic pulse shock wave transmitter.
    Type: Application
    Filed: September 29, 2016
    Publication date: January 17, 2019
    Inventors: Yi LIU, Fuchang LIN, Yuan PAN, Qin ZHANG, Hua LI, Zhiyuan LI, Siwei LIU
  • Patent number: 10107838
    Abstract: The present invention provides an online monitoring circuit of the series compensation spark gap divider return circuit. Said series compensation spark gap divider return circuit includes a voltage equalization link and a voltage sampling link. Said voltage link includes the capacitor C which series said voltage equalization link. Said online monitoring circuit includes the voltage sampling input module, series compensation current input module and the compare module. Said sampling voltage input module after amplified the voltage of the two ends of the series capacitor C converts it into direct current signal.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: October 23, 2018
    Assignees: STATE GRID COOPERATION OF CHINA, CHINA ELECTRIC POWER RESEARCH INSTITUTE
    Inventors: Guofu Li, Hui Yu, Zhiyuan Li, Yongliang Li
  • Publication number: 20170189496
    Abstract: A method for the treatment and/or the prevention of a disease or a symptom related to dysfunction of regulatory T cell immunomodulation includes administering to a subject in need thereof compositions that regulate regulatory T cell immunomodulatory function, in which the compositions may be prepared by contacting starting materials with phosphorylation pathway-related factors, the agonists or the antagonists thereof. The phosphorylation pathway-related factors are selected from: proto-oncogene protein PIM1 and the coding sequence thereof. The regulation is achieved by regulating the activity of regulators of regulatory T cells selected from the group: FOXP3, IL-2, GITR, CTLA4, and a combination thereof.
    Type: Application
    Filed: March 9, 2017
    Publication date: July 6, 2017
    Applicant: Institut Pasteur of Shanghai, Chinese Academy of Sciences
    Inventors: Bin Li, Zhiyuan Li, Fang Lin, Zhimei Gao, Zuojia Chen, Andy Tsun, Kongchen Li
  • Publication number: 20150149102
    Abstract: The present invention provides an online monitoring circuit of the series compensation spark gap divider return circuit, said series compensation spark gap divider return circuit includes voltage equalization link and the voltage sampling link; Said voltage link includes the capacitor C which series said voltage equalization link; Said online monitoring circuit includes the voltage sampling input module, series compensation current input module and the compare module; Said sampling voltage input module after amplified the voltage of the two ends of the series capacitor C converts it into direct current signal Udivide voltage; Said series compensation current input module after amplified the current signal of said series capacitor converts it into direct current voltage signal UCT; Said compare module realizes online monitoring the running state of said series spark gap divider return circuit though comparing said Udivide voltage and said UCT.
    Type: Application
    Filed: May 2, 2013
    Publication date: May 28, 2015
    Inventors: Guofu Li, Hui Yu, Zhiyuan Li, Yongliang Li
  • Publication number: 20150073043
    Abstract: A method for the treatment and/or the prevention of a disease or a symptom related to dysfunction of regulatory T cell immunomodulation includes administering to a subject in need thereof compositions that regulate regulatory T cell immunomodulatory function, in which the compositions may be prepared by contacting starting materials with phosphorylation pathway-related factors, the agonists or the antagonists thereof. The phosphorylation pathway-related factors are selected from: proto-oncogene protein PIM1 and the coding sequence thereof. The regulation is achieved by regulating the activity of regulators of regulatory T cells selected from the group: FOXP3, IL-2, GITR, CTLA4, and a combination thereof.
    Type: Application
    Filed: January 21, 2013
    Publication date: March 12, 2015
    Inventors: Bin Li, Zhiyuan Li, Fang Lin, Zhimei Gao, Zuojia Chen, Andy Tsun, Kongchen Li
  • Patent number: 8819137
    Abstract: This disclosure discloses a system and a method for sharing mobile internet service. The system comprises: a mobile client node configured to send a message for requesting a shared service; and a mobile agent peer-to-peer network including multiple mobile agent peer-to-peer nodes which are configured to receive the message from the mobile client node and provide for the mobile client node the shared service requested by the message. This disclosure uses the mobile agent peer-to-peer node to receive from the mobile client node the message for requesting the shared service and provide the shared service according to message, to solve the problem that transmission and sharing of large files among mobile terminals can not be implemented in the related art, and thus to implement the sharing of resources among mobile terminals.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: August 26, 2014
    Assignee: ZTE Corporation
    Inventors: Zhiping Wang, Ruchuan Wang, Zhiyuan Li, He Xu
  • Publication number: 20140013825
    Abstract: An apparatus for testing the air permeability in the thickness direction of a resin matrix composite material layer includes a mold having a cavity and a covering plate, a loading apparatus, a temperature controlling apparatus, a vacuuming apparatus, and a flow detecting element. An air inlet is connected to the flow detecting element, and an air outlet is connected to the vacuuming apparatus. The covering plate has a through-hole with upper and lower ventilation pieces. The loading apparatus addresses the upper ventilation piece. A test specimen is laid flat between the ventilation pieces. Employment of the present invention allows for accurate testing of air permeability of pre-impregnated material in the thickness direction of the resin matrix composite material layer under different pressure and temperature conditions.
    Type: Application
    Filed: December 31, 2011
    Publication date: January 16, 2014
    Applicants: SHANGHAI AIRCRAFT MANUFACTURING CO., LTD, COMMERCIAL AIRCRAFT CORPORATION OF CHINA, LTD.
    Inventors: Weiping Liu, Dongmei Zhang, Yizhu Zheng, Xu Wang, Jiazhi Su, Xiaoxing Ma, Jun Liu, Zhiyuan Li, Xinjing Wang, Min Li, Yizhuo Gu, Chaobo Xin, Yanxia Li, Zuoguang Zhang
  • Publication number: 20140013826
    Abstract: An apparatus for testing the gas permeability on the inward facing direction of a pre-impregnated resin matrix composite material layer includes a mold, a loading apparatus, a temperature control apparatus, a vacuuming apparatus, and a flow detecting element. A test specimen is laid flat inside the mold between airtight sealing elements that leave exposed two ends of the test specimen on the inward facing direction of the layer. An air inlet and an air outlet respectively are arranged on the mold and correspond to the two exposed ends of the test specimen. The inlet is connected to the flow detecting element, and the outlet is connected to the vacuuming apparatus. Air is forced to move in a vacuumed cavity along the inward facing direction of the layer. Testing of air permeability of pre-impregnated material in solidification technique is allowed via adjustments of pressure and temperature.
    Type: Application
    Filed: December 31, 2011
    Publication date: January 16, 2014
    Applicants: SHANGHAI AIRCRAFT MANUFACTURING CO LTD, COMMERCIAL AIRCRAFT CORPORATION OF CHINA LTD
    Inventors: Weiping Liu, Dongmei Zhang, Xiaoxing Ma, Jun Liu, Zhiyuan Li, Xinjing Wang, Yizhu Zheng, Xu Wang, Jiazhi Su, Chaobo Xin, Yizhuo Gu, Min Li, Yanxia Li, Zuoguang Zhang
  • Publication number: 20130122046
    Abstract: Use of an ubiquitination pathway-related factor, its agonist or antagonist in the preparation of a composition for regulating FOXP3, IL-2, and/or IFN-? activity, in which the ubiquitination pathway-related factor is selected from: Toll-like receptor, ubiquitin ligase, pro-inflammatory cytokine family receptor, and/or its coding sequence. The new type of regulatory factors can regulate regulatory T cells and immune system by regulating FOXP3, IL-2, and/or IFN-? activity. The regulatory factors and their derivatives can also be used as immunoadjuvant for treating or preventing major diseases (such as, infectious diseases and tumor, etc).
    Type: Application
    Filed: July 11, 2011
    Publication date: May 16, 2013
    Applicant: INSTITUT PASTEUR OF SHANGHAI, CAS
    Inventors: Bin Li, Fang Lin, Zuojia Chen, Zhiyuan Li, Fan Pan