Patents by Inventor Zhiyuan Yang

Zhiyuan Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117430
    Abstract: A genome-specific gene sequence fragment of female Acipenser Dabryanus and a method for identifying the sex of Acipenser Dabryanus are disclosed. The gene sequence fragment of Acipenser Dabryanus is used to identify the sex of Acipenser Dabryanus. The method includes: performing PCR amplification on the DNA of the Acipenser Dabryanus to be tested, and judging that the Acipenser Dabryanus to be tested is female when a resultant product from the amplification shows 3 bands on an agarose gel and the Acipenser Dabryanus to be tested is male when a resultant product from the amplification shows 2 bands on an agarose gel, alternatively, judging that the Acipenser Dabryanus to be tested is female when a resultant fragment from the amplification has a 1402 bp band and it is male if there is no 1402 bp band. The gene sequence fragment is used to quickly and efficiently identify the sex of Acipenser Dabryanus.
    Type: Application
    Filed: February 23, 2023
    Publication date: April 11, 2024
    Applicant: CHINESE STURGEON RESEARCH INSTITUTE OF CTG
    Inventors: Lei CHEN, Zhiyuan LI, Yuanjin YANG, Yacheng HU, Xin ZHU, Hejun DU, Dezhi ZHANG
  • Publication number: 20240085057
    Abstract: A fume hood structure for a portable water heater includes a hood body. The hood body includes a top plate and two side plates respectively located at two sides of the top plate. An interior of the hood body is transversely provided with an air deflector which is rotatable. Two ends of the air deflector are each provided with a rotating lug. A rotating shaft base is arranged on the side plate. A rotating shaft is provided on the rotating shaft base, and extends inwardly and transversely to be connected with the rotating lug.
    Type: Application
    Filed: November 15, 2023
    Publication date: March 14, 2024
    Inventors: Xianwei FENG, Qi YANG, Zhiyuan MA, Deqing CHEN
  • Publication number: 20240077229
    Abstract: A portable water heater includes an inner bracket and a thermostatic chamber. A burner and a heat exchanger are arranged in the inner bracket. An upper end of the heat exchanger is provided with a fume collecting hood. The burner includes multiple fire rows arranged side by side, and the fire rows are connected to each other through a gas-distributing rod. The gas-distributing rod is provided with a segmented self-priming valve. A gas-regulating valve is provided on a gas inlet pipe. An inlet end of an internal heat-exchanging pipe of the heat exchanger is communicated with a cold water feeding pipe. The thermostatic chamber has a water inlet connected to a hot water delivering pipe and a water outlet connected to a hot water discharging pipe, and a connecting pipe is provided between the cold water feeding pipe and the hot water delivering pipe.
    Type: Application
    Filed: November 9, 2023
    Publication date: March 7, 2024
    Inventors: Xianwei FENG, Qi YANG, Zhiyuan MA, Deqing CHEN
  • Patent number: 11924539
    Abstract: A method for controlling image capture includes: receiving, from a movable device, an image of a target imaging area; adjusting, by a first control apparatus, one or more first imaging parameters for imaging the target imaging area based at least in part on the image to obtain one or more first adjusted imaging parameters; adjusting, by operating on an interactive interface of a second control apparatus, one or more second imaging parameters for imaging the target imaging area based at least in part on the image to obtain one or more second adjusted imaging parameters, the interactive interface being configured to receive user interaction to control an attitude of a gimbal device configured on the movable device, the gimbal device carrying an imaging device for imaging the targeted area; and sending, by the first control apparatus and/or the second control apparatus, an instruction carrying the one or more first adjusted imaging parameters and the one or more second adjusted imaging parameters to the movable
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: March 5, 2024
    Assignee: SZ DJI TECHNOLOGY CO., LTD.
    Inventors: Heli Zhong, Bingzhen Yang, Lifu Yu, Zhiyuan Zhang
  • Publication number: 20230374140
    Abstract: The present technology relates generally to compositions that specifically recognize and bind to a NDC80 peptide complexed with a major histocompatibility antigen (e.g., HLA-A*02). The compositions of the present technology are useful in methods for treating NDC80-associated diseases (e.g., cancers) in a subject in need thereof.
    Type: Application
    Filed: October 8, 2021
    Publication date: November 23, 2023
    Inventors: Martin KLATT, Tao DAO, David A. SCHEINBERG, Zhiyuan YANG, Jianying LIU
  • Publication number: 20230330815
    Abstract: A Block-Type structured diamond grinding wheel with adaptive supply of instantaneous Cooling, includes a grinding wheel substrate and several grinding wheel units, each including an execution mechanism, a push mechanism, and an instantaneous Cooling mechanism. Various structured patterns are provided on an upper surface of the grinding unit in the execution mechanism, and a heat sink is disposed at a lower surface. During operation, a tangential grinding force generated by the grinding unit and a workpiece presses a sprayer to spray nano fluid into an operating region, to implement instantaneous Cooling of grinding wheel. When wear occurs in a grinding unit of a grinding wheel, a corresponding grinding unit may be replaced to extend the service life of the grinding wheel, and production costs are reduced. A special surface structure of the grinding unit further enhances a cooling effect, thereby improving a surface quality of a workpiece.
    Type: Application
    Filed: June 21, 2023
    Publication date: October 19, 2023
    Inventors: Jiaming LIU, XIaohong ZHANG, Liwei NING, Jia DUAN, Xiong TANG, Wei LI, Zhiyuan YANG, Wanyi TIAN, Shiguo TENG
  • Publication number: 20230293687
    Abstract: Described herein are immune cells comprising: a T-cell receptor (TCR) and a chimeric stimulating receptor (CSR) that comprises (i) a ligand-binding module that is capable of binding or interacting with a target ligand; (ii) a transmembrane domain; and (iii) a CD30 costimulatory domain, in which the CSR in the immune cells lacks a functional primary signaling domain. Also provided herein are methods of using the same or components thereof (e.g., the CSR) for therapeutic treatment of cancers (e.g., solid tumor cancers).
    Type: Application
    Filed: July 29, 2021
    Publication date: September 21, 2023
    Inventors: Cheng Liu, Hongbing Zhang, Zhiyuan Yang, Pengbo Zhang, Yixiang Xu, Guangyuan Xiong, Ziyou Cui
  • Publication number: 20230141962
    Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.
    Type: Application
    Filed: August 4, 2022
    Publication date: May 11, 2023
    Inventors: Cheng LIU, Hongbing Zhang, Zhiyuan Yang, Jingyi Xiang, Ziyou Cui, Jianying Liu
  • Patent number: 11613573
    Abstract: The present application provides chimeric antibody-TCR constructs comprising an antigen-binding module that specifically binds to a target antigen and a T cell receptor module capable of recruiting at least one TCR-associated signaling molecule. Also provided are methods of making and using these constructs.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: March 28, 2023
    Assignee: EUREKA THERAPEUTICS, INC.
    Inventors: Lucas Horan, Yiyang Xu, Zhiyuan Yang, Hong Liu, Javier Morales, Lianxing Liu
  • Publication number: 20220348629
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Application
    Filed: April 8, 2022
    Publication date: November 3, 2022
    Inventors: Jingwei LU, Zhiyuan YANG, Cheng LIU, Hong LIU, Yiyang XU, Su YAN, Vivien Wai-Fan CHAN, Lucas HORAN
  • Patent number: 11440952
    Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: September 13, 2022
    Assignee: InvisiShield Technologies Ltd.
    Inventors: Cheng Liu, Hongbing Zhang, Zhiyuan Yang, Jingyi Xiang, Ziyou Cui, Jianying Liu
  • Publication number: 20220267420
    Abstract: Provided herein are compositions, kits, and methods for manufacturing cells for adoptive cell therapy comprising (a) an engineered receptor, vector encoding an engineered receptor, or engineered immune cell expressing such engineered receptor or comprising such vector; and (b) a Fox P3 targeting agent.
    Type: Application
    Filed: February 14, 2019
    Publication date: August 25, 2022
    Applicants: Memorial Sloan Kettering Cancer Center, Eureka Therapeutics, Inc.
    Inventors: David A. SCHEINBERG, Cheng LIU, Zhiyuan YANG, Lianxing LIU, Shaohua Xu, Pei WANG, Yiyang XU
  • Patent number: 11421013
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: August 23, 2022
    Assignee: EUREKA THERAPEUTICS, INC.
    Inventors: Jingwei Lu, Zhiyuan Yang, Cheng Liu, Hong Liu, Yiyang Xu, Su Yan, Vivien Wai-Fan Chan, Lucas Horan
  • Publication number: 20220185910
    Abstract: The present application provides constructs comprising an antibody moiety that specifically binds to PSMA (e.g., PSMA expressed on the surface of a cell). Also provided are methods of making and using these constructs.
    Type: Application
    Filed: June 17, 2019
    Publication date: June 16, 2022
    Inventors: Hong LIU, Hongruo YUN, Xiaomei GE, Zhiyuan YANG, Lianxing LIU, Pengbo ZHANG, Yixiang XU, Shan LI, Lucas HORAN
  • Publication number: 20220119501
    Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.
    Type: Application
    Filed: October 14, 2021
    Publication date: April 21, 2022
    Inventors: Cheng LIU, Hongbing ZHANG, Zhiyuan YANG, Jingyi XIANG, Ziyou CUI, Jianying LIU
  • Publication number: 20210253665
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Application
    Filed: February 22, 2021
    Publication date: August 19, 2021
    Inventors: Jingwei LU, Zhiyuan YANG, Cheng LIU, Hong LIU, Yiyang XU, Su YAN, Vivien Wai-Fan CHAN, Lucas HORAN
  • Publication number: 20210101954
    Abstract: The present application provides chimeric antibody-TCR constructs comprising an antigen-binding module that specifically binds to a target antigen and a T cell receptor module capable of recruiting at least one TCR-associated signaling molecule. Also provided are methods of making and using these constructs.
    Type: Application
    Filed: April 24, 2018
    Publication date: April 8, 2021
    Inventors: Lucas HORAN, Yiyang XU, Zhiyuan YANG, Hong LIU, Javier MORALES, Lianxing LIU
  • Patent number: 10822389
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 3, 2020
    Assignee: EUREKA THERAPEUTICS, INC.
    Inventors: Jingwei Lu, Zhiyuan Yang, Cheng Liu, Hong Liu, Yiyang Xu, Su Yan, Vivien Wai-Fan Chan, Lucas Horan
  • Publication number: 20200115434
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Application
    Filed: October 29, 2019
    Publication date: April 16, 2020
    Inventors: Jingwei LU, Zhiyuan YANG, Cheng LIU, Hong LIU, Yiyang XU, Su YAN, Vivien Wai-Fan CHAN, Lucas HORAN
  • Patent number: 10464988
    Abstract: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: November 5, 2019
    Assignee: EUREKA THERAPEUTICS, INC.
    Inventors: Jingwei Lu, Zhiyuan Yang, Cheng Liu, Hong Liu, Yiyang Xu, Su Yan, Vivien Wai-Fan Chan, Lucas Horan