Abstract: Disclosed in the present invention are a lignan derivative, a preparation method therefor and the use thereof. The structure of the lignan derivative is as shown in a formula I, wherein in the formula, the definition of each substituent is as described in the description and claims. The lignan derivative of the present invention can be used as an inhibitor of mitochondrial respiratory chain complex I to inhibit mitochondrial oxidative phosphorylation and ATP generation, and can also be used for preventing and/or treating diseases associated with the elevated activity or expression of the mitochondrial respiratory chain complex I or enhanced mitochondrial oxidative phosphorylation.

Abstract: A high-throughput hybridization and reading method for biochips uses probes with different marks to specifically connect single nucleotide loci by conducting connection between the probes and target genes at different temperatures, and performing hybridization at the same temperature after the probes are connected, thereby achieving hybridization detection for various loci in a single chip. The method enables fast detection for multiple loci as required by personalized medicine. The detection is high-throughput and systematized and provides highly visualized and highly accurate results. The method allows detection for different loci at different hybridization temperatures to be done simultaneously. The method features highly uniform and repeatable detection, making biochips more efficient and utility in terms of detection. Besides, the chip is easy to prepare and use, thus having a good promotional value.

Abstract: A high-throughput hybridization and reading method for biochips uses probes with different marks to specifically connect single nucleotide loci by conducting connection between the probes and target genes at different temperatures, and performing hybridization at the same temperature after the probes are connected, thereby achieving hybridization detection for various loci in a single chip. The method enables fast detection for multiple loci as required by personalized medicine. The detection is high-throughput and systematized and provides highly visualized and highly accurate results. The method allows detection for different loci at different hybridization temperatures to be done simultaneously. The method features highly uniform and repeatable detection, making biochips more efficient and utility in terms of detection. Besides, the chip is easy to prepare and use, thus having a good promotional value.

Abstract: A high-throughput hybridization and reading method for biochips uses probes with different marks to specifically connect single nucleotide loci by conducting connection between the probes and target genes at different temperatures, and performing hybridization at the same temperature after the probes are connected, thereby achieving hybridization detection for various loci in a single chip. The method enables fast detection for multiple loci as required by personalized medicine. The detection is high-throughput and systematized and provides highly visualized and highly accurate results. The method allows detection for different loci at different hybridization temperatures to be done simultaneously. The method features highly uniform and repeatable detection, making biochips more efficient and utility in terms of detection. Besides, the chip is easy to prepare and use, thus having a good promotional value.

Abstract: A high-throughput hybridization and reading method for biochips uses probes with different marks to specifically connect single nucleotide loci by conducting connection between the probes and target genes at different temperatures, and performing hybridization at the same temperature after the probes are connected, thereby achieving hybridization detection for various loci in a single chip. The method enables fast detection for multiple loci as required by personalized medicine. The detection is high-throughput and systematized and provides highly visualized and highly accurate results. The method allows detection for different loci at different hybridization temperatures to be done simultaneously. The method features highly uniform and repeatable detection, making biochips more efficient and utility in terms of detection. Besides, the chip is easy to prepare and use, thus having a good promotional value.

Abstract: Provided are a conjugate of memantine and arctigenin, and a pharmaceutical composition comprising the conjugate. The conjugate can treat diseases associated with A? or Tau protein pathways, such as Alzheimer's disease or Parkinson's disease.

Abstract: Provided are a conjugate of memantine and arctigenin, and a pharmaceutical composition comprising the conjugate. The conjugate can treat diseases associated with A? or Tau protein pathways, such as Alzheimer's disease or Parkinson's disease.

Abstract: An apparatus for testing the performance of Radio Frequency Identification (RFID) system, comprising: a drive motor, that is driven according to a preset speed; a turntable, that is fixed on to a plane of drive motor, said turntable including a gadget to fasten the label, the gadget makes the under-test label perpendicular to the plane and rotates with the turntable; a reader antenna, that is set to a fixed position around the turntable and connected to the under-test reader, wherein direction of main lobe axes of the reader antenna and direction of the main lobe axes of antenna built in the under-test label are in the same plane. The present invention utilizes circular motion in the lab to simulate rectilinear motion in the practical application. The present invention reduces the volume of RFID test device and the space in the lab, and improves the flexibility of the test.

Abstract: An apparatus for testing the performance of Radio Frequency Identification (RFID) system, comprising: a drive motor, that is driven according to a preset speed; a turntable, that is fixed on to a plane of drive motor, said turntable including a gadget to fasten the label, the gadget makes the under-test label perpendicular to the plane and rotates with the turntable; a reader antenna, that is set to a fixed position around the turntable and connected to the under-test reader, wherein direction of main lobe axes of the reader antenna and direction of the main lobe axes of antenna built in the under-test label are in the same plane. The present invention utilizes circular motion in the lab to simulate rectilinear motion in the practical application. The present invention reduces the volume of RFID test device and the space in the lab, and improves the flexibility of the test.