Patents by Inventor Zhiyun XU
Zhiyun XU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11547558Abstract: A heart valve prosthesis anchored to an interventricular septum. The heart valve prosthesis includes a valve supporting frame and a fixing device. The valve supporting frame includes a valve stitching section and an artificial valve. The artificial valve is fixedly connected to the valve stitching section. The fixing device includes a fixing and supporting section and a fixing member. One end of the fixing and supporting section is connected to a proximal end of the valve stitching section, and another end of the fixing and supporting section is connected to the interventricular septum of a patient by the fixing member, to support the heart valve prosthesis and prevent the heart valve prosthesis from axially moving.Type: GrantFiled: October 23, 2017Date of Patent: January 10, 2023Assignee: NINGBO JENSCARE BIOTECHNOLOGY CO., LTD.Inventors: Shiwen Lv, Yibin Li, Zhiyun Xu, Zhi Chen, Fanglin Lu, Jianan Li
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Publication number: 20210282925Abstract: A heart valve prosthesis anchored to an interventricular septum. The heart valve prosthesis includes a valve supporting frame and a fixing device. The valve supporting frame includes a valve stitching section and an artificial valve. The artificial valve is fixedly connected to the valve stitching section. The fixing device includes a fixing and supporting section and a fixing member. One end of the fixing and supporting section is connected to a proximal end of the valve stitching section, and another end of the fixing and supporting section is connected to the interventricular septum of a patient by the fixing member, to support the heart valve prosthesis and prevent the heart valve prosthesis from axially moving.Type: ApplicationFiled: October 23, 2017Publication date: September 16, 2021Inventors: Shiwen LV, Yibin LI, Zhiyun XU, Zhi CHEN, Fanglin LU, Jianan LI
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Patent number: 10548709Abstract: The present invention provides an aortic arch intraoperative stent, wherein the aortic arch intraoperative stent comprising a main body (17) and one to three branches (5, 6, 7), The aortic arch intraoperative stent connects several circular waveform rings together via a cover membrane (25) to form the main body (17) and the branches (5, 6, 7), wherein each circular waveform ring comprises a circular elastic wire formed through head-to-tail connection. In addition, the present invention also provides a manufacturing method for the aortic arch intraoperative stent, comprising the following steps of: providing a cover membrane mandrel (40); making an inner membrane; assembling circular waveform rings; making an outer membrane; suturing a proximal fabric (12); and suturing a distal fabric (13).Type: GrantFiled: December 30, 2014Date of Patent: February 4, 2020Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.Inventors: Yongsheng Wang, Zhiyun Xu, Deyuan Zhang, Caiping Liu, Benhao Xiao
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Patent number: 10449049Abstract: A prosthesis (100) for preventing a valve regurgitation, comprising a fixation unit (110), a connection piece (120) and a closure assisting piece (130); the fixation unit (110) comprises a fixation piece (111) and an anchor (112); the connection piece (120) is flexible, and a distal section thereof is connected to a proximal section of the fixation piece (111), and a proximal section thereof is connected to a distal section of the closure assisting piece (130); the fixation piece (111) is fixed on the atrial wall or a valve ring of a patient via the anchor (112); the deployed width of the fixation piece (111) is less than two-thirds of the circumference of a valve tissue annulus; the closure assisting piece (130) is located between autologous valve leaflets of the patient when in a free state; the maximum width of the closure assisting piece (130) is less than the maximum deployed width of a single autologous valve leaflet; and the proximal end of the anchor (112) is provided with an anti-disengagement end (1Type: GrantFiled: January 9, 2017Date of Patent: October 22, 2019Assignee: NINGBO JENSCARE BIOTECHNOLOGY CO., LTD.Inventors: Yibin Li, Shiwen Lv, Zhiyun Xu, Jianan Li, Deyuan Zheng, Zhi Chen
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Patent number: 10398547Abstract: An implant with anchoring device for heart valve disease comprises a cardiac valve prosthesis (1), at least two sets of anchoring needles (2) and at least two sets of anchoring needle releasing devices (3). Proximal end of the anchoring needles (2) are provided with anti-disengagement ends (23). The anchoring needle releasing devices (3) are detachably connected to the cardiac valve prosthesis (1). The anchoring needle releasing devices (3) comprise delivery tubes (31) and shafts (32). Distal sections of the anchoring needle releasing devices (3) are in preset shapes. The shafts (32) can be pushed to force the anchoring needles (2) to move toward the distal ends of the delivery tubes (31), so that the cardiac valve prosthesis (1) is fixed between autogenous tissue (6) and the anti-disengagement ends (23) to achieve accurate positioning and firm anchoring of the cardiac valve prosthesis (1).Type: GrantFiled: January 5, 2017Date of Patent: September 3, 2019Assignee: NINGBO JENSCARE BIOTECHNOLOGY CO., LTD.Inventors: Jianan Li, Shiwen Lv, Zhiyun Xu, Yibin Li, Zhi Chen
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Patent number: 9955971Abstract: In a method for treating an aortic arch disease, after an intraoperative stent is expanded in an aorta and at least one arch branch vessel, and before the vessel is exactly anastomosed with an incision, by blocking a thoracic aorta between the incision and an arch branch vessel closest to the incision, the intraoperative stent in the thoracic aorta is also blocked, so that blood is prevented from flowing from the incision, and a proximal orifice of the intraoperative stent, and the low body perfusion may be recovered in advance, thereby reducing the circulatory arrest time of the low body perfusion and reducing the time of ischemia of visceral organs and lower limbs of a patient. Meanwhile, the flow of a cerebral perfusion through the right axillary artery may be recovered to a normal flow in advance, and the time of ischemia of the brain of the patient is reduced.Type: GrantFiled: December 30, 2015Date of Patent: May 1, 2018Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.Inventors: Zhiyun Xu, Xiangman Zhang, Lin Han, Deyuan Zhang, Benhao Xiao
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Publication number: 20170189030Abstract: In a method for treating an aortic arch disease, after an intraoperative stent is expanded in an aorta and at least one arch branch vessel, and before the vessel is exactly anastomosed with an incision, by blocking a thoracic aorta between the incision and an arch branch vessel closest to the incision, the intraoperative stent in the thoracic aorta is also blocked, so that blood is prevented from flowing from the incision, and a proximal orifice of the intraoperative stent, and the low body perfusion may be recovered in advance, thereby reducing the circulatory arrest time of the low body perfusion and reducing the time of ischemia of visceral organs and lower limbs of a patient. Meanwhile, the flow of a cerebral perfusion through the right axillary artery may be recovered to a normal flow in advance, and the time of ischemia of the brain of the patient is reduced.Type: ApplicationFiled: December 30, 2015Publication date: July 6, 2017Applicant: Lifetech Scientific (Shenzhen) Co., Ltd.Inventors: Zhiyun Xu, Xiangman Zhang, Lin Han, Deyuan Zhang, Benhao Xiao
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Publication number: 20170112618Abstract: A prosthesis (100) for preventing a valve regurgitation, comprising a fixation unit (110), a connection piece (120) and a closure assisting piece (130); the fixation unit (110) comprises a fixation piece (111) and an anchor (112); the connection piece (120) is flexible, and a distal section thereof is connected to a proximal section of the fixation piece (111), and a proximal section thereof is connected to a distal section of the closure assisting piece (130); the fixation piece (111) is fixed on the atrial wall or a valve ring of a patient via the anchor (112); the deployed width of the fixation piece (111) is less than two-thirds of the circumference of a valve tissue annulus; the closure assisting piece (130) is located between autologous valve leaflets of the patient when in a free state; the maximum width of the closure assisting piece (130) is less than the maximum deployed width of a single autologous valve leaflet; and the proximal end of the anchor (112) is provided with an anti-disengagement end (1Type: ApplicationFiled: January 9, 2017Publication date: April 27, 2017Applicant: NINGBO JENSCARE BIOTECHNOLOGY CO., LTD.Inventors: Yibin LI, Shiwen LV, ZHIYUN XU, Jianan LI, Deyuan ZHENG, Zhi CHEN
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Publication number: 20170112622Abstract: An implant with anchoring device for heart valve disease comprises a cardiac valve prosthesis (1), at least two sets of anchoring needles (2) and at least two sets of anchoring needle releasing devices (3). Proximal end of the anchoring needles (2) are provided with anti-disengagement ends (23). The anchoring needle releasing devices (3) are detachably connected to the cardiac valve prosthesis (1). The anchoring needle releasing devices (3) comprise delivery tubes (31) and shafts (32). Distal sections of the anchoring needle releasing devices (3) are in preset shapes. The shafts (32) can be pushed to force the anchoring needles (2) to move toward the distal ends of the delivery tubes (31), so that the cardiac valve prosthesis (1) is fixed between autogenous tissue (6) and the anti-disengagement ends (23) to achieve accurate positioning and firm anchoring of the cardiac valve prosthesis (1).Type: ApplicationFiled: January 5, 2017Publication date: April 27, 2017Inventors: Jianan Li, Shiwen Lv, Zhiyun Xu, Yibin Li, Zhi Chen
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Publication number: 20160310258Abstract: The present invention provides an aortic arch intraoperative stent, wherein the aortic arch intraoperative stent comprising a main body (17) and one to three branches (5, 6, 7), The aortic arch intraoperative stent connects several circular waveform rings together via a cover membrane (25) to form the main body (17) and the branches (5, 6, 7), wherein each circular waveform ring comprises a circular elastic wire formed through head-to-tail connection. In addition, the present invention also provides a manufacturing method for the aortic arch intraoperative stent, comprising the following steps of: providing a cover membrane mandrel (40); making an inner membrane; assembling circular waveform rings; making an outer membrane; suturing a proximal fabric (12); and suturing a distal fabric (13).Type: ApplicationFiled: December 30, 2014Publication date: October 27, 2016Applicant: Lifetech Scientific (Shenzhen) Co., Ltd.Inventors: Yongsheng WANG, Zhiyun XU, Deyuan ZHANG, Caiping LIU, Benhao XIAO