Patents by Inventor Zhonggui He

Zhonggui He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220016251
    Abstract: In the field of medical technologies, there is a triglyceride prodrug based on lymphatic-mediated transport, particularly a triglyceride prodrug with different linking chains for lymphatic-mediated transport, and a method for preparing the same and use thereof in drug delivery. The prodrugs are linked by different linking bonds and methods for synthesizing the same. The structures of the prodrugs are as follows: wherein X, R1, R2, n, m are as described in the claims and specification. A mechanism of digestion and absorption of glycerol in the gastrointestinal tract is simulated by using a triglyceride-like structure, so as to promote the lymphatic transport of the drugs and avoid a first-pass effect. The prodrugs have targeting properties and can significantly increase or improve oral bioavailability.
    Type: Application
    Filed: July 27, 2021
    Publication date: January 20, 2022
    Applicants: SHENYANG PHARMACEUTICAL UNIVERSITY, SUZHOU YUTAI PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventors: Jin SUN, Zhonggui HE, Chutong TIAN
  • Patent number: 9393314
    Abstract: Disclosed are meloxicam eye drops and the preparation method and use thereof. The eye drops contain active ingredient meloxicam or a pharmaceutically acceptable salt thereof, a solubilizer, a stabilizer, a pH adjusting agent, an antimicrobial agent and an osmotic pressure adjusting agent, wherein the solubilizer is one of hydroxypropyl-?-cyclodextrin, sulfobutylether-?-cyclodextrin, and ?-cyclodextrin or a mixture thereof, and the stabilizer is one of polymer povidone, sodium hyaluronate, and hypromellose or a mixture thereof.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: July 19, 2016
    Assignee: KANGYA OF NINGXIA PHARMACEUTICALS CO., LTD
    Inventors: Yajun Yang, Zhonggui He, Yimeng Qin
  • Publication number: 20160022822
    Abstract: Disclosed are meloxicam eye drops and the preparation method and use thereof. The eye drops contain active ingredient meloxicam or a pharmaceutically acceptable salt thereof, a solubilizer, a stabilizer, a pH adjusting agent, an antimicrobial agent and an osmotic pressure adjusting agent, wherein the solubilizer is one of hydroxypropyl-?-cyclodextrin, sulfobutylether-?-cyclodextrin, and ?-cyclodextrin or a mixture thereof, and the stabilizer is one of polymer povidone, sodium hyaluronate, and hypromellose or a mixture thereof.
    Type: Application
    Filed: October 28, 2013
    Publication date: January 28, 2016
    Applicant: KANGYA OF NINGXIA PHARMACEUTICALS CO., LTD.
    Inventors: Yajun Yang, Zhonggui He, Yimeng Qin