Patents by Inventor Zhongming Li

Zhongming Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11963787
    Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: April 23, 2024
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Zhongming Li, Angela Belcher
  • Publication number: 20240122529
    Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
    Type: Application
    Filed: December 13, 2023
    Publication date: April 18, 2024
    Inventors: Zhongming Li, Angela Belcher
  • Publication number: 20240114636
    Abstract: The present disclosure provides a tamper-proofing electronic seal. The tamper-proofing electronic seal includes a shell, a lead seal rope, and a lead seal label. The lead seal label comprises a chip, an antenna circuit, a power supply, a power switch, and a potential detection circuit which are electrically connected. The power switch is arranged on a circuit, electrically connected to the chip, of the power supply. The potential detection circuit is electrically connected to the antenna circuit and the chip. A fixing hole and a locking hole are provided at positions, corresponding the potential detection circuit and the power switch, of the interior of the shell; the fixing end of the lead seal rope is clamped in the shell through the fixing hole; the use state of the electronic seal can be accurately marked, and the electronic seal is prevented from being tampered with or recycled.
    Type: Application
    Filed: December 20, 2022
    Publication date: April 4, 2024
    Applicant: Xiamen Innov Information Science And Technology Co., Ltd.
    Inventors: Zhongming LI, Axia LIN
  • Publication number: 20240008733
    Abstract: A system includes a laparoscope including a first port, a second port, and an optical system. The optical system includes a first port coupling, a shortwave infrared (SWIR) sensor coupling configured to couple to a SWIR sensor, and a visible-light sensor coupling configured to couple to a visible-light sensor. The optical system is configured to optically couple to at least the second port of the laparoscope via the first port coupling. The optical system is configured to receive a detection SWIR beam from the second port and direct at least a portion of the detection SWIR beam to the SWIR sensor coupling. The optical system is further configured to receive a detection visible-light beam from the second port and direct at least a portion of the detection visible-light beam to the visible-light sensor coupling.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 11, 2024
    Applicant: Cision Vision, Inc.
    Inventor: Zhongming LI
  • Patent number: 11828734
    Abstract: A loading apparatus for rock fracturing simulation includes an upper cover plate, a lower cover plate, lateral pressure pieces, and an acoustic measurement module top pillar. There are at least two lateral pressure pieces which are provided with a force applying face respectively for transmitting a radial force to a core sample. The upper cover plate, the lower cover plate and the lateral pressure pieces enclose a loading space for placing the core sample, and the lateral pressure pieces can slide along a radial direction of the core sample and relative to the upper cover plate or the lower cover plate. The lateral pressure pieces are provided with a sensor inserting hole for allowing a sensor to pass through respectively, and the sensor is attached to an outer peripheral wall of the core sample.
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: November 28, 2023
    Assignee: China University of Geosciences (Beijing)
    Inventors: Jinchuan Zhang, Xiwei Wang, Zhongming Li, Pei Li, Shijing Chen, Yang Liu, Xiaoliang Wei
  • Publication number: 20230309907
    Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
    Type: Application
    Filed: January 12, 2023
    Publication date: October 5, 2023
    Inventors: Zhongming Li, Angela Belcher
  • Publication number: 20230160817
    Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.
    Type: Application
    Filed: January 3, 2023
    Publication date: May 25, 2023
    Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
  • Patent number: 11592391
    Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: February 28, 2023
    Assignee: University of Notre Dame du Lac
    Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
  • Patent number: 11576608
    Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: February 14, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Zhongming Li, Angela Belcher
  • Publication number: 20210356367
    Abstract: A loading apparatus for rock fracturing simulation includes an upper cover plate, a lower cover plate, lateral pressure pieces, and an acoustic measurement module top pillar. There are at least two lateral pressure pieces which are provided with a force applying face respectively for transmitting a radial force to a core sample. The upper cover plate, the lower cover plate and the lateral pressure pieces enclose a loading space for placing the core sample, and the lateral pressure pieces can slide along a radial direction of the core sample and relative to the upper cover plate or the lower cover plate. The lateral pressure pieces are provided with a sensor inserting hole for allowing a sensor to pass through respectively, and the sensor is attached to an outer peripheral wall of the core sample.
    Type: Application
    Filed: July 27, 2021
    Publication date: November 18, 2021
    Inventors: Jinchuan Zhang, Xiwei Wang, Zhongming Li, Pei Li, Shijing Chen, Yang Liu, Xiaoliang Wei
  • Publication number: 20210003504
    Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.
    Type: Application
    Filed: May 18, 2020
    Publication date: January 7, 2021
    Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
  • Publication number: 20200245921
    Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
    Type: Application
    Filed: February 4, 2020
    Publication date: August 6, 2020
    Inventors: Zhongming Li, Angela Belcher
  • Patent number: 10677722
    Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: June 9, 2020
    Assignee: University of Notre Dame du Lac
    Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
  • Publication number: 20180246032
    Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.
    Type: Application
    Filed: April 5, 2017
    Publication date: August 30, 2018
    Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
  • Patent number: 7585669
    Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: September 8, 2009
    Assignee: Synergy America, Inc.
    Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
  • Publication number: 20080199952
    Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
    Type: Application
    Filed: May 14, 2007
    Publication date: August 21, 2008
    Applicant: Synergy America, Inc.
    Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
  • Patent number: 7217791
    Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: May 15, 2007
    Assignee: Synergy America, Inc.
    Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
  • Publication number: 20040213803
    Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
    Type: Application
    Filed: November 6, 2003
    Publication date: October 28, 2004
    Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
  • Patent number: D1012681
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: January 30, 2024
    Assignee: Zhongshan Lanlun Castor Manufacturing Co., Ltd
    Inventor: Zhongming Li