Patents by Inventor Zhong Xiong

Zhong Xiong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11932705
    Abstract: Provided herein are cyclic polypeptide compounds that can, e.g., bind specifically to human proprotein convertase subtilisin/kexin type 9 (PCSK9) and optionally also inhibit interaction between human PCSK9 and human low density lipoprotein receptor (LDLR), and pharmaceutical compositions comprising one or more of these compounds. Also provided are methods of reducing LDL cholesterol level in a subject in need thereof that include administering to the subject one or more of the cyclic polypeptide compounds or a pharmaceutical composition provided herein.
    Type: Grant
    Filed: August 29, 2022
    Date of Patent: March 19, 2024
    Assignees: MERCK SHARP & DOHME LLC, RA PHARMACEUTICALS, INC.
    Inventors: Alonso Ricardo, Thomas Joseph Tucker, Nicolas Cedric Boyer, Ketki Ashok Dhamnaskar, Zhong Ma, Angela Dawn Kerekes, Chengwei Wu, Sookhee Nicole Ha, Hyewon Youm, Elisabetta Bianchi, Danila Branca, Raffaele Ingenito, Willy Costantini, Aurash Shahripour, Yusheng Xiong
  • Publication number: 20240035612
    Abstract: A foldable support, wherein the foldable support comprises two first supporting members, two second supporting members, two first assembly portions, and two second assembly portions. The first supporting members are able to be rotatably unfolded relative to the second supporting members or be drawn together and folded up. First linking members are respectively movable connected to the two first assembly portions close to the ends of a second supporting arm, and the other ends of the two second linking members are respectively correspondingly hinged to the two second supporting members. The two second assembly portions are respectively correspondingly hinged to the two second supporting members, and each of the second assembly portions, close to the ends of the first supporting arm, are movable connected to first linking members. The two first linking members are respectively correspondingly hinged to the two first supporting members.
    Type: Application
    Filed: May 4, 2023
    Publication date: February 1, 2024
    Inventors: Ming-Yong CHAI, Zhong-Xiong CHENG, Bao-Lin CHEN, Chia-Hung WU
  • Patent number: 7952444
    Abstract: CMOS power oscillator and a method of frequency modulating a CMOS power oscillator. The oscillator comprises a transformer-based feedback CMOS power oscillator circuit formed on a chip-substrate, the oscillator circuit including a transformer coupled to a transistor; means for modulating the capacitance of the transformer to the chip-substrate for frequency modulating an output of the power oscillator.
    Type: Grant
    Filed: August 8, 2006
    Date of Patent: May 31, 2011
    Assignee: Agency for Science, Technology and Research
    Inventor: Yong Zhong Xiong
  • Publication number: 20090315630
    Abstract: CMOS power oscillator and a method of frequency modulating a CMOS power oscillator. The oscillator comprises a transformer-based feedback CMOS power oscillator circuit formed on a chip-substrate, the oscillator circuit including a transformer coupled to a transistor; means for modulating the capacitance of the transformer to the chip-substrate for frequency modulating an output of the power oscillator.
    Type: Application
    Filed: August 8, 2006
    Publication date: December 24, 2009
    Applicant: AGENCY FO SCIENCE, TECHNOLOGY AND RESEARCH
    Inventor: Yong Zhong Xiong
  • Patent number: 7581902
    Abstract: A method for preparing a class of highly stabilized and soil-dispersible nanoparticles and using the nanoparticles as a remediation technology for immobilizing toxic metals at toxic metal contaminated sites. The method employs a composition containing select polysaccharides (starch or cellulose) as a stabilizer for the nanoparticles in a liquid carrier, and results in suspensions of nanoparticles of desired size and mobility in water, soils or sediments. The stabilizer can facilitate controlling the dispersibility of the nanoparticles in the liquid carrier. An effective amount of the composition is delivered to a contaminated site so that the nanoparticles can immobilize one or more toxic metals of the contaminated site.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: September 1, 2009
    Assignee: Auburn University
    Inventors: Dongye Zhao, Zhong Xiong, Mark Barnett, Ruiqiang Liu, Willie F. Harper, Feng He
  • Patent number: 7517456
    Abstract: Methods for treating landfill leachate taught herein comprise: (a) coagulatively settling leachate; (b) filtering the resultant supernatant liquid through multistage cartridges; (c) filtering the filtered liquid by reverse osmosis; and (d) treating the resultant liquid with chlorine-based oxidant. These methods provide the advantages of efficient wastewater treatment, compact equipment size, short process flow, and low startup and operational costs.
    Type: Grant
    Filed: July 4, 2006
    Date of Patent: April 14, 2009
    Assignee: Shenzhen JDL Environmental Protection Ltd.
    Inventors: Zhi Min Liao, Jing Kui Guo, Yu He Huang, Jing Zou, Zhi Qiang Chen, Rui Zhi Dai, Wen Yan Shi, Jian Zhong Xiong, Hai Ying Ji
  • Publication number: 20070203388
    Abstract: A method for preparing a class of highly stabilized and soil-dispersible nanoparticles and using the nanoparticles as a remediation technology for immobilizing toxic metals at toxic metal contaminated sites. The method employs a composition containing select polysaccharides (starch or cellulose) as a stabilizer for the nanoparticles in a liquid carrier, and results in suspensions of nanoparticles of desired size and mobility in water, soils or sediments. The stabilizer can facilitate controlling the dispersibility of the nanoparticles in the liquid carrier. An effective amount of the composition is delivered to a contaminated site so that the nanoparticles can immobilize one or more toxic metals of the contaminated site.
    Type: Application
    Filed: February 28, 2007
    Publication date: August 30, 2007
    Inventors: Dongye Zhao, Zhong Xiong, Mark Barnett, Ruiqiang Liu, Willie Harper, Feng He
  • Publication number: 20070003370
    Abstract: Methods for treating landfill leachate taught herein comprise: (a) coagulatively settling leachate; (b) filtering the resultant supernatant liquid through multistage cartridges; (c) filtering the filtered liquid by reverse osmosis; and (d) treating the resultant liquid with chlorine-based oxidant. These methods provide the advantages of efficient wastewater treatment, compact equipment size, short process flow, and low startup and operational costs.
    Type: Application
    Filed: July 4, 2006
    Publication date: January 4, 2007
    Inventors: Zhi Min LIAO, Jing Kui GUO, Yu He HUANG, Jing ZOU, Zhi Qiang CHEN, Rui Zhi DAI, Wen Yan SHI, Jian Zhong XIONG, Hai Ying JI
  • Patent number: 7019593
    Abstract: Circuits, such as a cascode amplifier or low noise amplifier, having terminals and a voltage-controlled and variable inductive load are disclosed. Any such circuit comprises an output terminal and a voltage-controlled and variable inductive loading network. The voltage-controlled and variable inductive loading network comprises a primary inductor having a first primary inductor terminal for coupling to a supply voltage, a second primary inductor terminal coupled to the output terminal, a secondary inductor sharing mutual inductance with the first inductor, and a variable resistance device having one terminal connected to a first secondary inductor terminal and another terminal connected to a second secondary inductor terminal, wherein the variable resistance device being dependant on mutual induction between the primary and secondary inductors provides loading at the output terminal.
    Type: Grant
    Filed: December 26, 2003
    Date of Patent: March 28, 2006
    Assignee: Agency For Science, Technology And Research
    Inventors: Nuntha Kumar Krishnasamy Maniam, Yong Zhong Xiong
  • Publication number: 20050140456
    Abstract: Circuits, such as a cascode amplifier or low noise amplifier, having terminals and a voltage-controlled and variable inductive load are disclosed. Any such circuit comprises an output terminal and a voltage-controlled and variable inductive loading network. The voltage-controlled and variable inductive loading network comprises a primary inductor having a first primary inductor terminal for coupling to a supply voltage, a second primary inductor terminal coupled to the output terminal, a secondary inductor sharing mutual inductance with the first inductor, and a variable resistance device having one terminal connected to a first secondary inductor terminal and another terminal connected to a second secondary inductor terminal, wherein the variable resistance device being dependant on mutual induction between the primary and secondary inductors provides loading at the output terminal.
    Type: Application
    Filed: December 26, 2003
    Publication date: June 30, 2005
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Nuntha Kumar Krishnasamy Maniam, Yong Zhong Xiong
  • Patent number: D968471
    Type: Grant
    Filed: February 21, 2021
    Date of Patent: November 1, 2022
    Inventor: Zhong Xiong