Patents by Inventor Zhongbing Zhang

Zhongbing Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150272923
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Application
    Filed: June 11, 2015
    Publication date: October 1, 2015
    Applicant: The University of Toledo
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Patent number: 9114126
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: August 25, 2015
    Assignee: THE UNIVERSITY OF TOLEDO
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Publication number: 20140031419
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Application
    Filed: October 3, 2013
    Publication date: January 30, 2014
    Applicant: The University of Toledo
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Publication number: 20120302630
    Abstract: Na/K-ATPase/Src ligands, assays and uses thereof are disclosed.
    Type: Application
    Filed: September 9, 2010
    Publication date: November 29, 2012
    Applicants: CHINESE ACADEMY OF MEDICAL SCIENCES, UNIVERSITY OF TOLEDO
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Patent number: D1017763
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: March 12, 2024
    Assignee: CHONGQING LIDONG MACHINERY & ELECTRIC CO., LTD
    Inventors: Qiping Zhang, Zhongbing Zhu, Daoyong Chen, Guolin Lu