Patents by Inventor Zhongbing Zhang

Zhongbing Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for optimization design of artificial reef structure
    Patent number: 12108744
    Abstract: Disclosed is a method for optimization design of an artificial reef structure. The method includes: arranging an artificial reef model to be tested on a test platform, testing a flow field to obtain flow field data and a pull force of an artificial reef, analyzing the flow field data to obtain a flow velocity reference point, and carrying out optimization analysis in combination with the flow field data and the pull force.
    Type: Grant
    Filed: May 29, 2024
    Date of Patent: October 8, 2024
    Assignee: GUANGDONG OCEAN UNIVERSITY
    Inventors: Guanglin Wu, Zhangfeng Yang, Hui Yang, Yan Tian, Yanli He, Zhenglin Tian, Jinbo Lin, Dongbin He, Huiling Zhang, Hongfei Mao, Chunhua Zeng, Yingchao Ma, Xiaofen Wang, Jintao Xu, Zhongbing Zhou
  • Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof
    Publication number: 20150272923
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Application
    Filed: June 11, 2015
    Publication date: October 1, 2015
    Applicant: The University of Toledo
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Na/K-ATPase ligands, ouabain antagonists, assays and uses thereof
    Patent number: 9114126
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: August 25, 2015
    Assignee: THE UNIVERSITY OF TOLEDO
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof
    Publication number: 20140031419
    Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
    Type: Application
    Filed: October 3, 2013
    Publication date: January 30, 2014
    Applicant: The University of Toledo
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
  • Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof
    Publication number: 20120302630
    Abstract: Na/K-ATPase/Src ligands, assays and uses thereof are disclosed.
    Type: Application
    Filed: September 9, 2010
    Publication date: November 29, 2012
    Applicants: CHINESE ACADEMY OF MEDICAL SCIENCES, UNIVERSITY OF TOLEDO
    Inventors: Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang