Patents by Inventor Zhongdang Xiao

Zhongdang Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7247384
    Abstract: The present invention provides for a practical method of grafting oligo- and/or poly(ethyleneglycol) (OEG and/or PEG) derivatives onto hydrogen-terminated silicon surfaces, including the surfaces of silicon scanning probe microscopy (SPM) tips, by hydrosilylation of OEG and/or PEG-terminated alkenes. This invention is related to the development of silicon-based bio-devices, including biochips, biosensors such as SPM probes, microarrays, micro-fluidic systems, and implantable microdevices. This invention is also a practical method to modify (many) SPM probe tips with OEG/PEG derivatives and to subsequently modify the tip apex with functional single molecules to improve the specificity and resolution of AFM imaging and measurements. The functional molecules include the dendritic adsorbates with a functional group at their focal point and with or without a tripod-shaped framework.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: July 24, 2007
    Assignee: The University of Houston
    Inventors: Chengzhi Cai, Chi Ming Yam, Zhongdang Xiao, Jianhua Gu
  • Publication number: 20040213910
    Abstract: The present invention provides for a practical method of grafting oligo- and/or poly(ethyleneglycol) (OEG and/or PEG) derivatives onto hydrogen-terminated silicon surfaces, including the surfaces of silicon scanning probe microscopy (SPM) tips, by hydrosilylation of OEG and/or PEG-terminated alkenes. This invention is related to the development of silicon-based bio-devices, including biochips, biosensors such as SPM probes, microarrays, micro-fluidic systems, and implantable microdevices. This invention is also a practical method to modify (many) SPM probe tips with OEG/PEG derivatives and to subsequently modify the tip apex with functional single molecules to improve the specificity and resolution of AFM imaging and measurements. The functional molecules include the dendritic adsorbates with a functional group at their focal point and with or without a tripod-shaped framework.
    Type: Application
    Filed: December 19, 2003
    Publication date: October 28, 2004
    Applicant: University of Houston
    Inventors: Chengzhi Cai, Chi Ming Yam, Zhongdang Xiao, Jianhua Gu