Abstract: The present disclosure provides a bainite geological drilling pipe, comprising the following chemical elements in percentage by mass: 0.14-0.22% of C, 0.2-0.55% of Si, 2.1-2.9% of Mn, 0.01-0.04% of Nb, 0.015-0.04% of Al, 0.001-0.005% of B, 0<N?0.007%, with the balance being Fe and inevitable impurities, wherein a content ratio of Al to N is Al/N?3. In addition, the present disclosure further provides a manufacturing method for the bainite geological drilling pipe, comprising the following steps: (1) performing smelting and casting on molten steel to obtain a pipe blank; (2) performing heating, piercing, continuous rolling and sizing on the pipe blank to obtain a pipe body; and (3) performing two-stage air cooling on the pipe body; in first-stage air cooling, performing air circular blowing cooling on the outer surface of the pipe body, the temperature before cooling is greater than or equal to Ar/3+50° C., the cooling rate is 5-15° C./s, and cooling to a temperature range from Bs-100° C. to Bs-50° C.

Abstract: Provided is a sweeping robot. The sweeping robot includes a chassis and a jet dust raising structure, and the jet dust raising structure is installed on the chassis, the jet dust raising structure has an air inlet, an air outlet and a jet channel connected to the air inlet and the air outlet, the air inlet is configured for air flow into the jet channel, the air outlet is located on a front side of the brush suction port of the sweeping robot.

Abstract: One example method includes receiving network topology information delivered by a topology manager, where the data center includes a plurality of servers, a plurality of electrical switches, and at least one optical cross-connect device. A data flow can be obtained. A routing policy can be configured for the data flow based on the network topology information, where the routing policy includes any one or a combination of the following routing policies: a first routing policy, where the first routing policy indicates to forward the data flow through an optical channel in the at least one optical cross-connect device; a second routing policy, where the second routing policy indicates to split the data flow into at least two sub-data flows for forwarding; or a third routing policy, where the third routing policy indicates to forward the data flow through an electrical switch of the plurality of electrical switches.

Abstract: The present invention relates to bispecific or biparatopic antigen binding proteins, polynucleotides encoding the same, and methods of making bispecific or biparatopic antigen binding proteins. Also described herein is a method to assemble IgG-like biparatopic or bispecific antibodies from VH only antigen binding proteins.

Abstract: Described herein are anti-SIRP? antibodies, polynucleotides encoding anti-SIRP? antibodies, host cells containing such polynucleotides, methods of making and using such anti-SIRP? antibodies or polynucleotides, pharmaceutical compositions containing such anti-SIRP? antibodies or polynucleotides, as well as mixtures or bispecific antibodies comprising such anti-SIRP? antibodies or polynucleotides encoding such mixtures or bispecific antibodies.

Abstract: Anti-CTLA4 antibodies, anti-PD1 antibodies, mixtures thereof, polynucleotides encoding such antibodies or mixtures, optionally carried on vectors, and methods of treatment utilizing such antibodies, mixtures, polynucleotides, or vectors are described herein. The anti-CTLA4 and anti-PD1 antibodies have particular sequences and properties. The methods of treatment include uses in treatment of cancer, infections, and immunodeficiency disorders.

Abstract: Anti-CTLA4 antibodies, anti-PD1 antibodies, mixtures thereof, polynucleotides encoding such antibodies or mixtures, optionally carried on vectors, and methods of treatment utilizing such antibodies, mixtures, polynucleotides, or vectors are described herein. The anti-CTLA4 and anti-PD1 antibodies have particular sequences and properties. The methods of treatment include uses in treatment of cancer, infections, and immunodeficiency disorders.

Abstract: Anti-CTLA4 antibodies, anti-PD1 antibodies, mixtures thereof, polynucleotides encoding such antibodies or mixtures, optionally carried on vectors, and methods of treatment utilizing such antibodies, mixtures, polynucleotides, or vectors are described herein. The anti-CTLA4 and anti-PD1 antibodies have particular sequences and properties. The methods of treatment include uses in treatment of cancer, infections, and immunodeficiency disorders.

Abstract: A lithography pupil shaping optical system and method for generating off-axis illumination mode. The invention is composed of illumination mode generation unit, rotatable wave plate, polarization beam splitter unit, ring I generation unit and ring II generation unit. Through selecting corresponding diffractive optical element and appropriate adjustment, this invention can generate various illumination modes including single ring illumination mode and double ring illumination mode. The intensity at pupil plane and the inner and outer diameters of the off-axis illumination mode can be adjusted continuously.

Abstract: A lithography pupil shaping optical system and method for generating off-axis illumination mode. The invention is composed of illumination mode generation unit, rotatable wave plate, polarization beam splitter unit, ring I generation unit and ring II generation unit. Through selecting corresponding diffractive optical element and appropriate adjustment, this invention can generate various illumination modes including single ring illumination mode and double ring illumination mode. The intensity at pupil plane and the inner and outer diameters of the off-axis illumination mode can be adjusted continuously.

Abstract: A detection apparatus and method for testing optical performance of beam shaping element used in ultraviolet lithography machine; The apparatus comprises visible wavelength laser and other optical units placed along the optical axis including, in order from laser side, (a) beam expander lens group, (b) beam splitter, (c) first far field imaging lens, (d) adjustable aperture or (e) CCD image sensor, (f) second far field imaging lens and (g) energy sensor. The detection apparatus is suitable be employed to detect the optical performance of beam shaping element working at any ultraviolet band, and provides the features of low cost, easy operation and quick measurement.

Abstract: A detection apparatus and method for testing optical performance of beam shaping element used in ultraviolet lithography machine; The apparatus comprises visible wavelength laser and other optical units placed along the optical axis including, in order from laser side, (a) beam expander lens group, (b) beam splitter, (c) first far field imaging lens, (d) adjustable aperture or (e) CCD image sensor, (f) second far field imaging lens and (g) energy sensor. The detection apparatus is suitable be employed to detect the optical performance of beam shaping element working at any ultraviolet band, and provides the features of low cost, easy operation and quick measurement.

Abstract: The present invention provides compositions and methods relating to human IgG1 and IgG3 Fc-conjugates which are resistant to free-radical mediated fragmentation and aggregation. The present invention also provides compositions and methods for making the Fc-conjugates of the invention.