Patents by Inventor Zhongke CHEN

Zhongke CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240393756
    Abstract: A control method includes obtaining an active time set in a predetermined time period that includes an active time instance at which a human body sensor assembly of a dishwasher detects human body activity in a predetermined region of the dishwasher, obtaining operation time of the dishwasher in the predetermined time period, predicting a tableware taking-out time point based on the active time set and the operation time, and controlling, at a target time point, the dishwasher to perform odor removal processing. The target time point is at a time length before the tableware taking-out time point.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 28, 2024
    Inventors: Yatao LIU, Zhongke WEI, Lixiao ZHANG, Le ZHAO, Hebin SHEN, Shiqiong CHEN, Qijun WU, Xueqing WANG
  • Publication number: 20240359148
    Abstract: The present disclosure discloses a preparation method of hydrosol solution, which includes: classifying total materials required for preparation of the hydrosol solution according to material properties, and allocating the classified materials to each feeding station of a hydrosol solution preparation system according to the material properties; turning on a heating system of the hydrosol solution preparation system to preheat a processing pipeline of a mixing and shearing device to make the temperature inside the processing pipeline meet processing requirements of the hydrosol solution; calculating and setting a flow rate of materials entering the processing pipeline for each material property; and starting the mixing and shearing device, synchronously opening the feeding stations, transporting each material to the processing pipeline according to the set flow rate, and simultaneously mixing and shearing all the materials by a first screw in the processing pipeline to obtain a homogeneous hydrosol solution.
    Type: Application
    Filed: November 19, 2023
    Publication date: October 31, 2024
    Inventors: Guodong ZHANG, Zhongke CHEN, Lei SHU, Bingqing ZHU, Xudong XIA
  • Publication number: 20240252993
    Abstract: The present disclosure discloses a preparation system of hydrosol solution, which includes a mixing and shearing device, a controller, and a plurality of feeding stations. The plurality of feeding stations are configured to store materials with different material properties, and all of the plurality of feeding stations are connected with the mixing and shearing device and transport the materials with different material properties to the mixing and shearing device. The controller is electrically connected with the plurality of feeding stations and controls material transportation speeds of the plurality of feeding stations. The controller is electrically connected with the mixing and shearing device and controls the operation of the mixing and shearing device, and the mixing and shearing device is configured to simultaneously mix and shear the materials with different material properties to obtain the hydrosol solution.
    Type: Application
    Filed: November 19, 2023
    Publication date: August 1, 2024
    Inventors: Guodong ZHANG, Zhongke CHEN, Xudong XIA, Lei SHU, Qing ZHU, Bingqing ZHU, Hui HUANG
  • Publication number: 20220281847
    Abstract: Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)actylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
    Type: Application
    Filed: October 25, 2021
    Publication date: September 8, 2022
    Inventors: Zhongke Chen, Fuping Liu, Lei Liu, Rudi Bao
  • Patent number: 11155534
    Abstract: Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: October 26, 2021
    Assignees: Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Shanghai Hansoh Biomedical Co., Ltd.
    Inventors: Zhongke Chen, Fuping Liu, Lei Liu, Rudi Bao
  • Publication number: 20200361909
    Abstract: Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 19, 2020
    Inventors: Zhongke CHEN, Fuping LIU, Lei LIU, Rudi BAO
  • Patent number: 10759782
    Abstract: Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: September 1, 2020
    Assignees: Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Shanhgai Hansoh Biomecial Co., Ltd.
    Inventors: Zhongke Chen, Fuping Liu, Lei Liu, Rudi Bao
  • Publication number: 20190077791
    Abstract: Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
    Type: Application
    Filed: December 23, 2016
    Publication date: March 14, 2019
    Applicants: Jiangsu Hansoh Pharmaceutical Group co., Ltd., Shanghai Hansoh Biomedical Co., Ltd.
    Inventors: Zhongke CHEN, Fuping LIU, Lei LIU, Rudi BAO