Patents by Inventor Zhongming Li
Zhongming Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240216219Abstract: The present disclosure discloses the composite film of oral liquid pharmaceutical packaging and the preparation method, the composite film comprises a polyester layer, an aluminum foil layer and a heat-sealing layer; the polyester layer and the aluminum foil layer, and the aluminum foil layer and the heat-sealing layer are both bonded with an adhesive agent; the adhesive agent is an aqueous polyurethane prepared from an aqueous polyurethane emulsion, citric acid, acetic acid and zirconium carbonate amine with a mass ratio of 100:1:1:10˜15. The present disclosure adopts carboxylic acid type aqueous polyurethane emulsion, citric acid, acetic acid and zirconium carbonate amine to prepare aqueous polyurethane, the zirconium metal can form stable complex system with citric acid, acetic acid and aqueous polyurethane emulsion, so that aqueous polyurethane emulsion can be demulsified and cured rapidly, shortening curing time, reducing curing temperature.Type: ApplicationFiled: March 15, 2023Publication date: July 4, 2024Inventors: Jinzhi BAI, Wanling LAN, Yan JIANG, Daiguo ZHAO, Xiaocong PU, Daiqun YUAN, Xinxing ZHU, Zhongming LI
-
Patent number: 11963787Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.Type: GrantFiled: January 12, 2023Date of Patent: April 23, 2024Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Zhongming Li, Angela Belcher
-
Publication number: 20240122529Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.Type: ApplicationFiled: December 13, 2023Publication date: April 18, 2024Inventors: Zhongming Li, Angela Belcher
-
Publication number: 20240114636Abstract: The present disclosure provides a tamper-proofing electronic seal. The tamper-proofing electronic seal includes a shell, a lead seal rope, and a lead seal label. The lead seal label comprises a chip, an antenna circuit, a power supply, a power switch, and a potential detection circuit which are electrically connected. The power switch is arranged on a circuit, electrically connected to the chip, of the power supply. The potential detection circuit is electrically connected to the antenna circuit and the chip. A fixing hole and a locking hole are provided at positions, corresponding the potential detection circuit and the power switch, of the interior of the shell; the fixing end of the lead seal rope is clamped in the shell through the fixing hole; the use state of the electronic seal can be accurately marked, and the electronic seal is prevented from being tampered with or recycled.Type: ApplicationFiled: December 20, 2022Publication date: April 4, 2024Applicant: Xiamen Innov Information Science And Technology Co., Ltd.Inventors: Zhongming LI, Axia LIN
-
Publication number: 20240008733Abstract: A system includes a laparoscope including a first port, a second port, and an optical system. The optical system includes a first port coupling, a shortwave infrared (SWIR) sensor coupling configured to couple to a SWIR sensor, and a visible-light sensor coupling configured to couple to a visible-light sensor. The optical system is configured to optically couple to at least the second port of the laparoscope via the first port coupling. The optical system is configured to receive a detection SWIR beam from the second port and direct at least a portion of the detection SWIR beam to the SWIR sensor coupling. The optical system is further configured to receive a detection visible-light beam from the second port and direct at least a portion of the detection visible-light beam to the visible-light sensor coupling.Type: ApplicationFiled: November 18, 2021Publication date: January 11, 2024Applicant: Cision Vision, Inc.Inventor: Zhongming LI
-
Patent number: 11828734Abstract: A loading apparatus for rock fracturing simulation includes an upper cover plate, a lower cover plate, lateral pressure pieces, and an acoustic measurement module top pillar. There are at least two lateral pressure pieces which are provided with a force applying face respectively for transmitting a radial force to a core sample. The upper cover plate, the lower cover plate and the lateral pressure pieces enclose a loading space for placing the core sample, and the lateral pressure pieces can slide along a radial direction of the core sample and relative to the upper cover plate or the lower cover plate. The lateral pressure pieces are provided with a sensor inserting hole for allowing a sensor to pass through respectively, and the sensor is attached to an outer peripheral wall of the core sample.Type: GrantFiled: July 27, 2021Date of Patent: November 28, 2023Assignee: China University of Geosciences (Beijing)Inventors: Jinchuan Zhang, Xiwei Wang, Zhongming Li, Pei Li, Shijing Chen, Yang Liu, Xiaoliang Wei
-
Publication number: 20230309907Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.Type: ApplicationFiled: January 12, 2023Publication date: October 5, 2023Inventors: Zhongming Li, Angela Belcher
-
Publication number: 20230160817Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.Type: ApplicationFiled: January 3, 2023Publication date: May 25, 2023Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
-
Patent number: 11592391Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.Type: GrantFiled: May 18, 2020Date of Patent: February 28, 2023Assignee: University of Notre Dame du LacInventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
-
Patent number: 11576608Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.Type: GrantFiled: February 4, 2020Date of Patent: February 14, 2023Assignee: Massachusetts Institute of TechnologyInventors: Zhongming Li, Angela Belcher
-
Publication number: 20210356367Abstract: A loading apparatus for rock fracturing simulation includes an upper cover plate, a lower cover plate, lateral pressure pieces, and an acoustic measurement module top pillar. There are at least two lateral pressure pieces which are provided with a force applying face respectively for transmitting a radial force to a core sample. The upper cover plate, the lower cover plate and the lateral pressure pieces enclose a loading space for placing the core sample, and the lateral pressure pieces can slide along a radial direction of the core sample and relative to the upper cover plate or the lower cover plate. The lateral pressure pieces are provided with a sensor inserting hole for allowing a sensor to pass through respectively, and the sensor is attached to an outer peripheral wall of the core sample.Type: ApplicationFiled: July 27, 2021Publication date: November 18, 2021Inventors: Jinchuan Zhang, Xiwei Wang, Zhongming Li, Pei Li, Shijing Chen, Yang Liu, Xiaoliang Wei
-
Publication number: 20210003504Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.Type: ApplicationFiled: May 18, 2020Publication date: January 7, 2021Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
-
Publication number: 20200245921Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.Type: ApplicationFiled: February 4, 2020Publication date: August 6, 2020Inventors: Zhongming Li, Angela Belcher
-
Patent number: 10677722Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.Type: GrantFiled: April 5, 2017Date of Patent: June 9, 2020Assignee: University of Notre Dame du LacInventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
-
Publication number: 20180246032Abstract: Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.Type: ApplicationFiled: April 5, 2017Publication date: August 30, 2018Inventors: Zhongming Li, Gregory Hartland, Masaru Ken Kuno
-
Patent number: 7585669Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: GrantFiled: May 14, 2007Date of Patent: September 8, 2009Assignee: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
-
Publication number: 20080199952Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: ApplicationFiled: May 14, 2007Publication date: August 21, 2008Applicant: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
-
Patent number: 7217791Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: GrantFiled: November 6, 2003Date of Patent: May 15, 2007Assignee: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
-
Publication number: 20040213803Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: ApplicationFiled: November 6, 2003Publication date: October 28, 2004Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
-
Patent number: D1012681Type: GrantFiled: February 14, 2022Date of Patent: January 30, 2024Assignee: Zhongshan Lanlun Castor Manufacturing Co., LtdInventor: Zhongming Li