Patents by Inventor Zhongming Zeng
Zhongming Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11951116Abstract: A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).Type: GrantFiled: December 1, 2020Date of Patent: April 9, 2024Assignee: SINGAPORE ZE&ZINTERNATIONAL PTE. LTDInventors: Zhongming Zeng, Ruyun Zhou
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Publication number: 20220395481Abstract: A bacteriostatic composition, a preparation method therefor and a use thereof are provided. The bacteriostatic composition includes one or more of a fatty acid and/or a salt thereof, one or more of a dicarboxylic acid and/or a salt thereof, one or more of an aromatic alcohol, and one or more of an aromatic acid and/or a salt thereof. The bacteriostatic composition may be made into an aqueous solution, a water-soluble gel, a foam, a spray, an ointment, a powder, a film, a capsule, a suppository, or a tablet, and may be used for inhibiting harmful microorganisms, particularly abnormal flora within the vagina.Type: ApplicationFiled: August 12, 2022Publication date: December 15, 2022Applicants: SHENZHEN EULIKAN BIOTECHNOLOGY CO., LTD, SINGAPORE ZE&Z INTERNATIONAL PTE. LTDInventor: Zhongming ZENG
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Publication number: 20210077516Abstract: A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).Type: ApplicationFiled: December 1, 2020Publication date: March 18, 2021Inventors: Zhongming Zeng, Ruyun Zhou
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Patent number: 10869878Abstract: A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.Type: GrantFiled: September 12, 2016Date of Patent: December 22, 2020Assignee: SINGAPORE ZE&Z INTERNATIONAL PTE. LTDInventors: Zhongming Zeng, Ruyun Zhou
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Publication number: 20200251934Abstract: A new RF/microwave energy harvesting device based on spintronics is provided. The device comprises at least one RF/microwave energy conversion element comprising a first magnetic layer connected to a RF/microwave signal receiving element; a non-magnetic space layer; and an energy conversion layer accumulating positive and negative charges at both of upper and lower ends of the RF/microwave energy conversion element to implement a conversion of a RF/microwave energy into a direct voltage signal. Compared with the prior art, the device has advantages such as a simple structure, a small size, a wide operating frequency and the like.Type: ApplicationFiled: March 24, 2017Publication date: August 6, 2020Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS(SINANO) CHINESE ACADEMY OF SCIENCESInventors: Zhongming ZENG, Giovanni FINOCCHIO, Bin FANG, Jialin CAI, Wei TANG, Xin LUO, Rongxin XIONG, Baoshun ZHANG
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Publication number: 20190231748Abstract: The present disclosure relates to an antimicrobial agent combination for use in preparing a composition for vagina. The combination of antimicrobial agents is strong in inhibiting against Escherichia coli, and/or Staphylococcus aureus, and/or Candida. The present disclosure also relates to a composition for vagina, which has a strong inhibition effect on Escherichia coli, and/or Staphylococcus aureus, and/or Candida. Being used in the vagina, the composition can promote the restoration of beneficial lactobacillus, increase the acidity of the vagina. It is suitable for modulating microecology and balancing microorganism in the vagina, and selectively decontaminating vagina.Type: ApplicationFiled: April 9, 2019Publication date: August 1, 2019Inventors: Zhongming Zeng, Wenyong Zhang, Kongyuan Wu
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Patent number: 9537087Abstract: A nanoscale tunnel magneto-resistance (TMR) sensor comprising an in-plane-magnetized reference layer and a free layer comprising interfacial perpendicular anisotropy, wherein the free layer comprises a sensing layer for sensing resistance as a function of applied magnetic field and is tunable to vary the direction of the sensing layer magnetization to be in-plane, canted, or out-of-plane.Type: GrantFiled: January 27, 2015Date of Patent: January 3, 2017Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Pedram Khalili Amiri, Zhongming Zeng, Kang L. Wang
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Publication number: 20160375045Abstract: A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.Type: ApplicationFiled: September 12, 2016Publication date: December 29, 2016Inventors: Zhongming Zeng, Ruyun Zhou
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Publication number: 20150137292Abstract: A nanoscale tunnel magneto-resistance (TMR) sensor comprising an in-plane-magnetized reference layer and a free layer comprising interfacial perpendicular anisotropy, wherein the free layer comprises a sensing layer for sensing resistance as a function of applied magnetic field and is tunable to vary the direction of the sensing layer magnetization to be in-plane, canted, or out-of-plane.Type: ApplicationFiled: January 27, 2015Publication date: May 21, 2015Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Pedram Khalili Amiri, Zhongming Zeng, Kang L. Wang
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Patent number: 8765819Abstract: The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.Type: GrantFiled: October 8, 2010Date of Patent: July 1, 2014Inventors: Zhongming Zeng, Ruyun Zhou
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Patent number: 8586549Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.Type: GrantFiled: June 29, 2012Date of Patent: November 19, 2013Assignees: Shenzhen Phlora Biotechnology Limited, HK Phlora Health Sci & Tech. LimitedInventors: Ruyun Zhou, Zhongming Zeng
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Publication number: 20120263667Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.Type: ApplicationFiled: June 29, 2012Publication date: October 18, 2012Applicants: HK PHLORA HEALTH SCI. & TECH. LIMITED, SHENZHEN PHLORA BIOTECHNOLOGY LIMITEDInventors: Ruyun ZHOU, Zhongming ZENG
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Publication number: 20120245132Abstract: The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.Type: ApplicationFiled: October 8, 2010Publication date: September 27, 2012Inventors: Zhongming Zeng, Ruyun Zhou
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Patent number: 8236576Abstract: A magnetic logic element with toroidal magnetic multilayers (5,6,8,9). The magnetic logic element comprises a toroidal closed section which is fabricated by etching a unit of magnetic multilayers (5,6,8,9) deposited on a substrate. Optionally, the magnetic logic element may also comprise a metal core (10) in the closed toroidal section. Said magnetic multilayers (5,6,8,9) unit is arranged on the input signal lines A, B, C and an output signal line O, and then is made into a closed toroidal. Subsequently, on the toroidal magnetic multilayered unit (5,6,8,9), the input signal lines A?, B?, C? and an output signal line O? are fabricated by etching. This magnetic logic element can reduce the demagnetization field and the shape anisotropy effectively, leading to the decrease of the reversal field of magnetic free layer. Furthermore, this magnetic logic element has stable working performance and long operation life of the device.Type: GrantFiled: April 11, 2007Date of Patent: August 7, 2012Assignee: Institute of Physics, Chinese Academy of SciencesInventors: Xiufeng Han, Zhongming Zeng, Yunan Han, Lixian Jiang, Zilong Peng, Wenshan Zhan
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Publication number: 20090273972Abstract: A magnetic logic element with toroidal magnetic multilayers (5,6,8,9). The magnetic logic element comprises a toroidal closed section which is fabricated by etching a unit of magnetic multilayers (5,6,8,9) deposited on a substrate. Optionally, the magnetic logic element may also comprise a metal core (10) in the closed toroidal section. Said magnetic multilayers (5,6,8,9) unit is arranged on the input signal lines A, B, C and an output signal line O, and then is made into a closed toroidal. Subsequently, on the toroidal magnetic multilayered unit (5,6,8,9), the input signal lines A?, B?, C? and an output signal line O? are fabricated by etching. This magnetic logic element can reduce the demagnetization field and the shape anisotropy effectively, leading to the decrease of the reversal field of magnetic free layer. Furthermore, this magnetic logic element has stable working performance and long operation life of the device.Type: ApplicationFiled: April 11, 2007Publication date: November 5, 2009Applicant: Institute of Physics, Chinese Academy of SciencesInventors: Xiufeng Han, Zhongming Zeng, Yunan Han, Lixian Jiang, Zilong Peng, Wenshan Zhan
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Publication number: 20090011284Abstract: The present invention relates to a core composite film for magnetic/nonmagnetic/magnetic multilayer thin film comprising a free magnetic layer, a spacer layer and a pinned magnetic layer. As the core composite film, it may be only the spacer layer is an LB film; and the spacer layer is an organic LB film consisting of materials with insulative, conductive or semiconductive character. As the core composite film, it may also be said free magnetic layer, spacer layer and pinned magnetic layer are all LB films; wherein the pinned magnetic layer and the free magnetic layer are organic films made of magnetic materials. The core composite film can be applied to a magnetic spin valve sensor, which can compose a magnetic induction unit of a magnetic spin valve sensor; and it can also be applied to a magnetic random access memory as a memory cell.Type: ApplicationFiled: March 24, 2006Publication date: January 8, 2009Inventors: Tianxing Wang, Zhongming Zeng, Guanxiang Du, Xiufeng Han, Zhenmin Hong, Gauquan Shi
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Publication number: 20080246023Abstract: The present invention relates to a transistor based on resonant tunneling effect of double barrier tunneling junctions comprising: a substrate, an emitter, a base, a collector and a first and a second tunneling barrier layers; wherein the first tunneling barrier layer is located between the emitter and the base, and the second tunneling barrier layer is located between the base and the collector; furthermore, the junction areas of the tunneling junctions which are formed between the emitter and the base and between the base and collector respectively are 1 ?m2˜10000 ?m2; the thickness of the base is comparable to the electron mean free path of material in the layer; the magnetization orientation is unbounded in one and only one pole of said emitter, base and collector. Because the double-barrier structure is used, it overcomes the Schottky potential between the base and the collector.Type: ApplicationFiled: April 8, 2005Publication date: October 9, 2008Applicant: INSTITUTE OF PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Zhongming Zeng, Xiufeng Han, Jiafeng Feng, Tianxing Wang, Guanxiang Du, Feifei Li, Wenshan Zhan
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Publication number: 20080193428Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.Type: ApplicationFiled: April 27, 2006Publication date: August 14, 2008Applicants: Shenzhen Phlora Biotechnology Limited, HK Phlora Health Science & Technology Ltd.Inventors: Ruyun Zhou, Zhongming Zeng
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Patent number: 7262170Abstract: A composition is disclosed for treating a patient suffering from abnormally high acidity in the vagina, wherein the vaginal pH value is lower than 4.0. The composition consists essentially of: (a) an effective amount of the following amino acids and/or physiologically acceptable salts thereof: glutamic acid, aspartic acid, isoleucine, phenylalanine and praline; (b) an effective amount of anti-fungi drugs; and (c) a sufficient amount of pharmaceutically acceptable acid or alkali, which results in a pH of the composition from 4.0-8.0; (d). One or more pharmaceutical carriers is used for the composition. The composition is particularly useful for treating vaginitis and fungal vaginitis associated with abnormally high vaginal acidity of a pH value less than 4.0.Type: GrantFiled: March 11, 2004Date of Patent: August 28, 2007Inventor: Zhongming Zeng
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Patent number: 6964949Abstract: The present invention relates to a pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina which comprises sucrose and/to maltose, to the use of certain sucrose and/or maltose, in preparing the pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, in particular to a method of stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, treating the reduction of gram-positive bacilli and the lowness of acidity in vagina as well as the vaginitis and the disturbance of vaginal bacterioflora accompanying the reduction of gram-positive bacilli, especially bacterial vaginal disease.Type: GrantFiled: August 18, 2003Date of Patent: November 15, 2005Assignee: Shanghai Jiao Da Onlly Co., Ltd.Inventor: Zhongming Zeng