Patents by Inventor Zhongping XIAO

Zhongping XIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220387477
    Abstract: The invention relates to a pharmaceutical composition containing alginate oligosaccharide diacid with formula (IV) or a pharmaceutically acceptable salt thereof, which can be used for preparing medicaments for treating Alzheimer's disease, Parkinson's disease, inflammation, pain, diabetes or vascular dementia.
    Type: Application
    Filed: October 26, 2020
    Publication date: December 8, 2022
    Inventors: Yingshen Jin, Xianliang Xin, Zhongping Xiao, Zhenqing Zhang, Meiyu Geng
  • Publication number: 20220356202
    Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.
    Type: Application
    Filed: July 8, 2022
    Publication date: November 10, 2022
    Inventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
  • Patent number: 11464794
    Abstract: The present invention relates to an alginic oligosaccharic diacid composition comprising a mannuronic diacid of Formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, m is selected from 0, 1 or 2, m? is selected from 0 or 1, and wherein the total weight of alginic oligosaccharic diacid wherein n=1-5 accounts for more than 60% of the total weight of the composition; the total weight of guluronic acids accounts for less than 50% of the total weight of the composition.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: October 11, 2022
    Assignees: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Meiyu Geng, Zhenqing Zhang, Yingshen Jin, Zhongping Xiao, Jian Ding
  • Patent number: 11384111
    Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: July 12, 2022
    Assignee: GREEN VALLEY (SHANGHAI) PHARMACEUTICAL CO., LTD. SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES
    Inventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
  • Patent number: 11155569
    Abstract: The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: October 26, 2021
    Assignee: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD.
    Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
  • Publication number: 20210260085
    Abstract: The present invention relates to an alginic oligosaccharic diacid composition comprising a mannuronic diacid of Formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, m is selected from 0, 1 or 2, m? is selected from 0 or 1, and wherein the total weight of alginic oligosaccharic diacid wherein n=1-5 accounts for more than 60% of the total weight of the composition; the total weight of guluronic acids accounts for less than 50% of the total weight of the composition.
    Type: Application
    Filed: June 28, 2019
    Publication date: August 26, 2021
    Inventors: Meiyu Geng, Zhenqing Zhang, Yingshen Jin, Zhongping Xiao, Jian Ding
  • Patent number: 10927137
    Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: February 23, 2021
    Assignee: Shanghai Green Valley Pharmaceutical Co., LTD.
    Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
  • Publication number: 20200385417
    Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.
    Type: Application
    Filed: December 27, 2017
    Publication date: December 10, 2020
    Inventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
  • Publication number: 20200055888
    Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.
    Type: Application
    Filed: August 15, 2016
    Publication date: February 20, 2020
    Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
  • Publication number: 20190345184
    Abstract: The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 14, 2019
    Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
  • Publication number: 20190073045
    Abstract: Keyset fingerprint sensors integrated within a keyset of an input device are described herein. A sensor key having an integrated fingerprint sensor is included within an arrangement of keys rather than being provided as a separate or external component. The fingerprint sensor operates to capture fingerprint data and initiate recognition processing responsive to actuation of the sensor key. In implementations, the cover includes a cut-out exposes the underlying fingerprint sensor so the fingerprint sensor is visible through an opening in the surface the key. Alternatively, the cover forms a surface designed to conceal the underlying fingerprint sensor. In this approach, the sensor key matches other keys within the arrangement of keys, such that the sensor key “blends-in” and is not visible from the surface of the key. In implementations, the sensor key includes a rigid PCB layer having fingerprint sensor componentry mounted to the PCB layer.
    Type: Application
    Filed: April 1, 2016
    Publication date: March 7, 2019
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Pengfei LEI, Jianxin JU, Nicolas J.C. SCHMITT, YuJian PENG, Tianyi WANG, Vicky CHEN, Zhongping XIAO, Rafl ZHANG