Patents by Inventor Zhongping XIAO
Zhongping XIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220387477Abstract: The invention relates to a pharmaceutical composition containing alginate oligosaccharide diacid with formula (IV) or a pharmaceutically acceptable salt thereof, which can be used for preparing medicaments for treating Alzheimer's disease, Parkinson's disease, inflammation, pain, diabetes or vascular dementia.Type: ApplicationFiled: October 26, 2020Publication date: December 8, 2022Inventors: Yingshen Jin, Xianliang Xin, Zhongping Xiao, Zhenqing Zhang, Meiyu Geng
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Publication number: 20220356202Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.Type: ApplicationFiled: July 8, 2022Publication date: November 10, 2022Inventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
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Patent number: 11464794Abstract: The present invention relates to an alginic oligosaccharic diacid composition comprising a mannuronic diacid of Formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, m is selected from 0, 1 or 2, m? is selected from 0 or 1, and wherein the total weight of alginic oligosaccharic diacid wherein n=1-5 accounts for more than 60% of the total weight of the composition; the total weight of guluronic acids accounts for less than 50% of the total weight of the composition.Type: GrantFiled: June 28, 2019Date of Patent: October 11, 2022Assignees: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCESInventors: Meiyu Geng, Zhenqing Zhang, Yingshen Jin, Zhongping Xiao, Jian Ding
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Patent number: 11384111Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.Type: GrantFiled: December 27, 2017Date of Patent: July 12, 2022Assignee: GREEN VALLEY (SHANGHAI) PHARMACEUTICAL CO., LTD. SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCESInventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
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Patent number: 11155569Abstract: The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction.Type: GrantFiled: December 27, 2017Date of Patent: October 26, 2021Assignee: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD.Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
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Publication number: 20210260085Abstract: The present invention relates to an alginic oligosaccharic diacid composition comprising a mannuronic diacid of Formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, m is selected from 0, 1 or 2, m? is selected from 0 or 1, and wherein the total weight of alginic oligosaccharic diacid wherein n=1-5 accounts for more than 60% of the total weight of the composition; the total weight of guluronic acids accounts for less than 50% of the total weight of the composition.Type: ApplicationFiled: June 28, 2019Publication date: August 26, 2021Inventors: Meiyu Geng, Zhenqing Zhang, Yingshen Jin, Zhongping Xiao, Jian Ding
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Patent number: 10927137Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.Type: GrantFiled: August 15, 2016Date of Patent: February 23, 2021Assignee: Shanghai Green Valley Pharmaceutical Co., LTD.Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
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Publication number: 20200385417Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.Type: ApplicationFiled: December 27, 2017Publication date: December 10, 2020Inventors: Meiyu Geng, Jian Ding, Zhenqing Zhang, Zhongping Xiao, Xiaoguang Du, Xianliang Xin
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Publication number: 20200055888Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.Type: ApplicationFiled: August 15, 2016Publication date: February 20, 2020Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
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Publication number: 20190345184Abstract: The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction.Type: ApplicationFiled: December 27, 2017Publication date: November 14, 2019Inventors: Zhongping Xiao, Zhenqing Zhang, Meiyu Geng, Jian Ding
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Publication number: 20190073045Abstract: Keyset fingerprint sensors integrated within a keyset of an input device are described herein. A sensor key having an integrated fingerprint sensor is included within an arrangement of keys rather than being provided as a separate or external component. The fingerprint sensor operates to capture fingerprint data and initiate recognition processing responsive to actuation of the sensor key. In implementations, the cover includes a cut-out exposes the underlying fingerprint sensor so the fingerprint sensor is visible through an opening in the surface the key. Alternatively, the cover forms a surface designed to conceal the underlying fingerprint sensor. In this approach, the sensor key matches other keys within the arrangement of keys, such that the sensor key “blends-in” and is not visible from the surface of the key. In implementations, the sensor key includes a rigid PCB layer having fingerprint sensor componentry mounted to the PCB layer.Type: ApplicationFiled: April 1, 2016Publication date: March 7, 2019Applicant: Microsoft Technology Licensing, LLCInventors: Pengfei LEI, Jianxin JU, Nicolas J.C. SCHMITT, YuJian PENG, Tianyi WANG, Vicky CHEN, Zhongping XIAO, Rafl ZHANG