Patents by Inventor Zhongxing Liang

Zhongxing Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCR4 Antagonists for the Treatment of Medical Disorders
    Publication number: 20160002174
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the treatment of proliferative conditions mediated by CXCR4 receptors. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 7, 2016
    Inventors: Hyunsuk Shim, Dennis C. Liotta, James P. Snyder, Weiqiang Zhan, Zhongxing Liang
  • CXCR4 ANTAGONISTS FOR THE TREATMENT OF MEDICAL DISORDERS
    Publication number: 20140039187
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the treatment of proliferative conditions mediated by CXCR4 receptors. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis.
    Type: Application
    Filed: February 13, 2012
    Publication date: February 6, 2014
    Inventors: Hyunsuk Shim, Dennis C. Liotta, James P. Snyder, Weiqiang Zhan, Zhongxing Liang
  • CXCR4 antagonists for the treatment of medical disorders
    Patent number: 8114884
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the treatment of proliferative conditions mediated by CXCR4 receptors. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: February 14, 2012
    Assignee: Emory University
    Inventors: Hyunsuk Shim, Dennis C. Liotta, James P. Snyder, Weiqiang Zhan, Zhongxing Liang
  • CXCR4 antagonists for the treatment of HIV infection
    Patent number: 8008312
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor, and in particular to inhibit viral entry of certain viruses. Certain compounds in particular can reduce entry of immunodeficiency virus (HIV) into a cell while not reducing the capacity of stem cells to proliferate, and therefore can be useful for long term treatment regimes. The compounds are useful in particular in the treatment or prevention of HIV infections.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: August 30, 2011
    Assignee: Emory University
    Inventors: Hyunsuk Shim, Dennis C. Liotta, James P. Snyder, Weiqiang Zhan, Zhongxing Liang
  • CXCR4 antagonists for the treatment of medical disorders
    Publication number: 20070054930
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the treatment of proliferative conditions mediated by CXCR4 receptors. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis.
    Type: Application
    Filed: January 9, 2006
    Publication date: March 8, 2007
    Inventors: Hyunsuk Shim, Dennis Liotta, James Snyder, Weiqiang Zhan, Zhongxing Liang
  • CXCR4 antagonists for the treatment of HIV infection
    Publication number: 20060264451
    Abstract: The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor, and in particular to inhibit viral entry of certain viruses. Certain compounds in particular can reduce entry of immunodeficiency virus (HIV) into a cell while not reducing the capacity of stem cells to proliferate, and therefore can be useful for long term treatment regimes. The compounds are useful in particular in the treatment or prevention of HIV infections.
    Type: Application
    Filed: January 9, 2006
    Publication date: November 23, 2006
    Inventors: Hyunsuk Shim, Dennis Liotta, James Snyder, Weiqiang Zhan, Zhongxing Liang