Abstract: A surgical hand piece comprises a generally cylindrical horn with a flange on one end. The flange has a central hub and first and second protruding sections. First and second polarized piezoelectric crystals are held against the flange such that rotative or torsional motion is induced in the horn.

Abstract: Polypeptides and proteins that specifically bind to and immunologically recognize CD276 are disclosed. Chimeric antigen receptors (CARs), anti-CD276 binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the polypeptides and proteins are also disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.

Abstract: Disclosed herein are human monoclonal antibodies that specifically bind both IGF-I and IGF-II with picomolar affinity and potently inhibit the IGF-IR signal transduction function. These antibodies are active in both an IgG and a scFv format. Bispecific forms of these antibodies are also disclosed. Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed herein. Also disclosed are pharmaceutical compositions including these antibodies. Methods are provided for treating a subject with cancer and for inhibiting phosphorylation of the insulin-like growth factor-I receptor. Methods are also provided for diagnosing cancer.

Abstract: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.

Abstract: The disclosure generally relates to compounds of formula (I), including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.

Abstract: The present disclosure provides a safe quick disconnect leakage protector, including a power supply circuit, a sampling circuit, a couple of single-pole single-throws, an on and off control circuit, and a testing circuit. The sampling circuit collects the leakage current signal between the live wire and the neutral wire and outputting the leakage current signal; the main control circuit receives the leakage current signal outputted from the sampling circuit, amplifies the leakage current signal, and outputs a grounding failure control signal when the leakage current reaches the predetermined value; the on and off control circuit receives the grounding failure control signal outputted from the main control circuit and controls the single-pole single-throw switches to disconnect the load from the external power supply according to the grounding failure control signal, thereby protecting the load and improves the safety of the leakage protection of an electrical appliance.

Abstract: A mobile network-based tenant network service implementation method and system and network elements are disclosed. The method includes: an MME of a mobile network performing identity authentication of a tenant network to which UE belongs on the UE; after the UE passes the identity authentication of tenant network, the MME selecting a local exchange node for the UE; the MME transmitting a creation/update message of a local exchange forwarding table to the local exchange node; the local exchange node creating or updating the local exchange forwarding table and generating a forwarding table entry of UE, wherein the forwarding table entry comprises identification information of UE; after UE bearers establishment are completed, the local exchange node writing UE bearer information into the forwarding table entry of UE; and the local exchange node implementing message forwarding of the tenant network according to the local forwarding table, thereby implementing a tenant network service.

Abstract: Disclosed is a thermoplastic elastomer composition comprising (i) about 10-60 wt % of at least one aliphatic polyamide; (ii) about 0.8-15 wt % of at least one graft-modified ethylene-olefin elastomeric copolymer; (iii) about 0.8-15 wt % of at least one graft-modified ethylene-propylene elastomeric copolymer, and (iv) about 35-85 wt % of at least one polyether-ester-amide block copolymer having a shore D of about 50-60 (as measured in accordance with ASTM D2240), with the total wt % of all components in the composition totaling to 100 wt %. Further disclosed herein is an article made from the thermoplastic elastomer composition disclosed above.

Abstract: A semiconductor device for electrostatic discharge protection includes a substrate, a first well and a second well formed in the substrate. The first and second wells are formed side by side, meeting at an interface, and have a first conductivity type and a second conductivity type, respectively. A first heavily doped region and a second heavily-doped region are formed in the first well. A third heavily doped region and a fourth heavily-doped region are formed in the second well. The first, second, third, and fourth heavily-doped regions have the first, second, second, and first conductivity types, respectively. Positions of the first and second heavily-doped regions are staggered along a direction parallel to the interface.

Abstract: A surgical hand piece comprises a generally cylindrical horn with a flange on one end. The flange has a central hub and first and second protruding sections. First and second polarized piezoelectric crystals are held against the flange such that rotative or torsional motion is induced in the horn.

Abstract: The present invention relates to the technical field of plugs and sockets for electrical appliances. Disclosed are a surface contact plug and socket, comprising a matching plug and socket; a plug contact piece connected with a plug electric wire is arranged on the lower surface of the plug; and a socket contact piece connected with a socket electric wire is arranged on the upper surface of the socket; when the plug is inserted into the socket, the plug contact piece vertically or obliquely meets the socket contact piece to cause surface contact electrification. The surface contact plug and socket of the present invention employ surface contact between contact pieces, enlarge the contact area and improve current transmission capacity since the plug and socket are of the same size, and therefore the contact is always reliable, and the more the plug and the socket are used, the more reliable the contact is.

Abstract: Disclosed herein are human monoclonal antibodies that specifically bind both IGF-I and IGF-II with picomolar affinity and potently inhibit the IGF-IR signal transduction function. These antibodies are active in both an IgG and a scFv format. Bispecific forms of these antibodies are also disclosed. Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed herein. Also disclosed are pharmaceutical compositions including these antibodies. Methods are provided for treating a subject with cancer and for inhibiting phosphorylation of the insulin-like growth factor-I receptor. Methods are also provided for diagnosing cancer.

Abstract: A calibration plate for measuring calibration of digital microscope and methods of using the same. The calibration plate comprises at least one calibration area formed with a surface structure which includes a plurality of grid cells arranged periodically, wherein at least part of boundary and/or at least part of apexes of each grid cell can be identified by an optical imaging system of the digital microscope. The invention also includes a digital microscope system equipped with the calibration plate.

Abstract: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.

Abstract: The invention relates to a human anti-dengue virus antibody (an anti-DENV antibody) that binds to a DENV envelope protein and is cross-reactive with DENV serotype 1, DENV serotype 2, DENV serotype 3, and DENV serotype 4. The disclosure provides an anti-DENV antibody that cross-reacts with and neutralizes all four DENV serotypes. Also provided is a nucleic acid molecule that encodes such an anti-DENV antibody. Also provided is a method to produce and use such an antibody or nucleic acid molecule encoding such an antibody.

Abstract: A virtual network auto-discovery and auto-configuration method and device thereof are provided. The method includes a tenant end system automatically discovering network virtualization edges (NVEs), the NVE initiating a VN identity authentication of the tenant end system, and the NVE automatically configuring a VN forwarding table of the VN after the tenant end system passes the VN identity authentication. The method and device solve the technical problem that virtual network configuration efficiency is low due to manually configuring the virtual network, and achieve the technical effect of improving the virtual network configuration efficiency.

Abstract: Disclosed is a multilayer wiring type double-interface IC card antenna module, comprising: an electrode diaphragm layer (1), a clamping base layer (2), an RFID antenna layer (3), an insulation layer (4) and a bridge layer (5). The electrode diaphragm layer (1) comprises an antenna and an electrode diaphragm. The clamping base layer (2) is arranged below the electrode diaphragm layer (1), and comprises eight first through hole points (21) located right below eight metal contacts on the electrode diaphragm. The MID antenna layer (3) is arranged below the clamping base layer (2), and comprises an RFID antenna, a connecting contact, a first chip attaching point and a second chip attaching point, the connecting contact and the first chip attaching point being connected to two ends of the RFID antenna.

Abstract: A semiconductor device for electrostatic discharge protection includes a substrate, a first well and a second well formed in the substrate. The first and second wells are formed side by side, meeting at an interface, and have a first conductivity type and a second conductivity type, respectively. A first heavily doped region and a second heavily-doped region are formed in the first well. A third heavily doped region and a fourth heavily-doped region are formed in the second well. The first, second, third, and fourth heavily-doped regions have the first, second, second, and first conductivity types, respectively. Positions of the first and second heavily-doped regions are staggered along a direction parallel to the interface.

Abstract: Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum alone or in combination with Centella Asiatica and methods for preventing or treating heart failure. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.

Abstract: A time check method and a base station are provided. The base station receives an authentication interaction message sent by an authentication interaction device; extracts time information in the authentication interaction message; and uses the time information to check local time. Before an Internet Key Exchange (IKE) connection is set up between the base station and a security gateway, relatively accurate time is obtained from an external authentication interaction device and is used for aligning the local time. Therefore, the cost of installing a clock component and a battery is saved, the time on the base station is trustworthy, and the security gateway is authenticated securely.