Abstract: A method for reconstructing three-dimensional faces is provided. The method includes: estimating a dynamic reconstruction parameter of a current video frame for three-dimensional face reconstruction by inputting, in response to a steady-state reconstruction parameter of the current video frame for the three-dimensional face reconstruction having been estimated by a pre-constructed teacher network model, the current video frame into a student network model distilled from the teacher network model; and reconstructing a three-dimensional face corresponding to the current video frame by inputting the steady-state reconstruction parameter and the dynamic reconstruction parameter into a pre-constructed three-dimensional deformation model.

Abstract: A method of constructing a high-performance anti-tampering database based on blockchain includes: acquiring change increment information corresponding to data to-be-stored through at least one of database nodes and storing the change increment information as bottom-layer data of all the database nodes based on a blockchain data structure; determining resultant data information based on the change increment information, indexing and then storing the resultant data information as top-layer data of all the database nodes; performing mutual-checks on stored top-layer data as per a predetermined mutual-checking period and performing self-checks on stored bottom-layer data as per a predetermined self-checking period, by the database nodes; and restoring the bottom-layer and/or top-layer data of the database nodes according to results of mutual-checks and self-checks, to realize database construction.

Abstract: Provided is a salt of an Syk inhibitor and a crystalline form thereof, and more specifically, provided are 5-fluoro-1-methyl-3-((5-(4-(oxetan-3-yl)piperazine-1)-yl)pyridin-2-yl)amino)-6-(1H-pyrazol-3-yl)quinoline-2(1H)-ketamine hydrochloride, a crystalline form thereof, a preparation method therefor, a pharmaceutical composition thereof and a use thereof. The hydrochloride of the compound represented by formula I and the crystalline form thereof have good salt-forming properties, high stability and low hygroscopicity, have advantages in terms of physical properties, safety and metabolic stability, and have value in prepared medicines.

Abstract: The present invention belongs to the field of drug crystals, relates to crystals of thiadiazole derivative DPP-IV inhibitors, and in particular relates to A and B type crystals of the compound as shown in formula 7. The crystals of the present invention have excellent stability. For example, under high temperature, high humidity or light test conditions, the material contents associated with the crystal of the compound of formula 7 do not change significantly. In addition, the crystal of the present invention also has a very good powder flowability and satisfies the requirements of drug preparation and production.

Abstract: The waterborne amino baking varnish is prepared with raw materials in percent by weight comprising: 25-40% of a waterborne polyurethane, 4-5% of a waterborne epoxy resin, 7-10% of a waterborne amino resin, 25-35% of deionized water, 1.5-2.5% of a pH regulator, 0.3-0.5% of a wetting agent, 0.2-0.6% of a defoamer, 0.5-1% of a dispersant, 1-5% of a cosolvent, 10-20% of a pigment and a filler, 2-5% of nano-alumina, 0.3-0.5% of lithium magnesium silicate, 0.3-0.5% of a thickener, and 0.5-0.8% of a leveling agent.

Abstract: The present invention belongs to the field of drug crystals, relates to crystals of thiadiazole derivative DPP-IV inhibitors, and in particular relates to A and B type crystals of the compound as shown in formula 7. The crystals of the present invention have excellent stability. For example, under high temperature, high humidity or light test conditions, the material contents associated with the crystal of the compound of formula 7 do not change significantly. In addition, the crystal of the present invention also has a very good powder flowability and satisfies the requirements of drug preparation and production.