Patents by Inventor Zhongzheng CAO

Zhongzheng CAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for editing RNAs
    Patent number: 11702658
    Abstract: The present application provides methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. The present application further provides deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: July 18, 2023
    Assignees: EDIGENE THERAPEUTICS (BEIJING) INC., PEKING UNIVERSITY
    Inventors: Pengfei Yuan, Yanxia Zhao, Nengyin Liu, Zexuan Yi, Gangbin Tang, Wensheng Wei, Liang Qu, Zongyi Yi, Shiyou Zhu, Chunhui Wang, Zhongzheng Cao, Zhuo Zhou
  • METHODS AND COMPOSITIONS FOR EDITING RNAS
    Publication number: 20220307020
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. Further provided are deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: April 15, 2020
    Publication date: September 29, 2022
    Inventors: Pengfei YUAN, Yanxia ZHAO, Nengyin LIU, Zexuan YI, Gangbin TANG, Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU
  • METHODS AND COMPOSITIONS FOR EDITING RNAS
    Publication number: 20220098587
    Abstract: The present application provides methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. The present application further provides deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: October 14, 2021
    Publication date: March 31, 2022
    Inventors: Pengfei YUAN, Yanxia ZHAO, Nengyin LIU, Zexuan YI, Gangbin TANG, Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU
  • COMPOSITIONS AND METHODS FOR HIGHLY EFFICIENT GENETIC SCREENING USING BARCODED GUIDE RNA CONSTRUCTS
    Publication number: 20220064633
    Abstract: Compositions, kits and methods are provided for genetic screening using one or more sets of guide RNA constructs having internal barcodes (“iBAR”). Each set has three or more guide RNA constructs targeting the same genomic locus, but embedded with different iBAR sequences.
    Type: Application
    Filed: December 20, 2019
    Publication date: March 3, 2022
    Applicants: Peking University, Edigene Biotechnology Inc.
    Inventors: Wensheng WEI, Shiyou ZHU, Zhongzheng CAO, Zhiheng LIU, Yuan HE, Pengfei YUAN
  • METHODS AND COMPOSITIONS FOR EDITING RNAS
    Publication number: 20210355494
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, and deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: October 12, 2019
    Publication date: November 18, 2021
    Inventors: Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU, Pengfei YUAN
  • METHODS AND COMPOSITIONS FOR EDITING RNAS
    Publication number: 20210310026
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, and deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: April 9, 2021
    Publication date: October 7, 2021
    Inventors: Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU, Pengfei YUAN
  • METHOD FOR SCREENING AND IDENTIFYING FUNCTIONAL LNCRNAS
    Publication number: 20210163936
    Abstract: Provided is a high-throughput method for screening or identifying long non-coding RNAs by CRISPR system, which uses paired guide RNA targeting the genomic sequence within the region spanning ?50 bp to +75 bp surrounding a splice donor site or a splice acceptor site of a long non-coding RNA.
    Type: Application
    Filed: April 2, 2018
    Publication date: June 3, 2021
    Inventors: Wensheng WEI, Ying LIU, Zhongzheng CAO, Yinan WANG, Yu GUO, Pengfei YUAN