Patents by Inventor Zhou LONG

Zhou LONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BARCODED TRANSPOSASE COMPLEX AND APPLICATION THEREOF IN HIGH-THROUGHPUT SEQUENCING
    Publication number: 20230174969
    Abstract: A barcoded transposase complex and an application thereof in high-throughput sequencing. Provided is a transposase recognition element, having the following structure: X(m)Y(f)N(n), in which X(m) represents a transposase recognition region of a double-stranded nucleic acid structure, Y(f) represents a spacer region of a single-stranded DNA structure, and N(n) represents a sample barcode of a single-stranded DNA structure. The high-molecular-weight DNA is processed using the barcoded transposase complex, to obtain a lot of barcoded DNA fragments. The barcoded DNA fragments obtained from each high-molecular-weight DNA are mixed to obtain a mixing sample. A carrier having a molecular barcode is adopted to capture. An exonuclease is adopted for processing, and then transposase is released. StLFR technology is adopted to construct a DNA library. The barcoded transposase complex can be applied to hybrid sequencing of a high-throughput sequencing platform.
    Type: Application
    Filed: May 18, 2020
    Publication date: June 8, 2023
    Inventors: Xiaofang CHENG, Yan ZOU, Dan CHEN, Zhou LONG, Lei CAO, Lin XIE, Ping LIU
  • METHOD FOR CONSTRUCTING SEQUENCING LIBRARY, OBTAINED SEQUENCING LIBRARY AND SEQUENCING METHOD
    Publication number: 20210214783
    Abstract: A method for constructing a sequencing library, a sequencing library and a sequencing method.
    Type: Application
    Filed: March 25, 2021
    Publication date: July 15, 2021
    Inventors: Luman CUI, Fei FAN, Wenwei ZHANG, Zhou LONG, Weimao WANG, Ou WANG